Clinical trials
Mood Disorders clinical trials
Below are recruiting mood disorders clinical trials, each written for real people, not researchers. We’re tracking 82 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07281729Enrolling by invitation
Suicide risk factors study for mood disorders
This study looks at why some people with mood disorders (like depression or bipolar disorder) think about or attempt suicide. By finding the risk factors, doctors hope to better prevent suicide. The study involves filling out questionnaires.
Shanghai, Shanghai MunicipalityAges 16–60 - NCT06408012Recruiting
Master platform for mood disorder trials
This trial creates a flexible platform to test new treatments for mood disorders like bipolar disorder and depression. It also includes healthy volunteers as a comparison group.
Calgary, AlbertaAges 16 years+ - NCT05637320Recruiting
Therapy study for children’s big emotions and mood
This study looks at how children’s emotions change during therapy for concerns like anxiety, depression, or disruptive behavior. It may help you and your child understand what kinds of therapy support might work best.
Guelph, OntarioAges 8–15 - NCT05797428Recruiting
Talk-based therapy to help teens cope with mood problems
This trial tests “logotherapy,” a type of counseling that helps people find meaning and purpose to cope with sadness or mood swings. It may help adolescents with mild to moderate-to-severe depression feel better and participate in structured therapy.
Kaohsiung City, Niaosong DistrictAges 15–24 - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Sunnyvale, CaliforniaAges 18–65 - NCT06532500Recruiting
CBT therapy for teen mood and anxiety
This study tests whether cognitive behavioural therapy (CBT) — a talk therapy that helps you change unhelpful thoughts and behaviors — can improve mood and anxiety in teens. If you're between 14 and 19 and have a mood or anxiety disorder, this therapy might be a good fit.
Toronto, OntarioAges 14–19 - NCT07033923Recruiting
Brain study of mood changes in depression and bipolar disorder
This study uses a mobile app and brain scans to understand day-to-day mood changes in people with depression or bipolar disorder. It may help doctors learn how to better predict and treat these conditions.
Paris, ParisAges 18 years+ - NCT00024635Recruiting
Understanding Mood and Anxiety Disorders Study
This research study evaluates people with mood disorders (like depression or bipolar disorder), anxiety disorders, or people without these conditions to better understand how these conditions develop and affect the brain. Researchers will ask questions and may do other assessments to learn more.
Bethesda, MarylandAges 3–99 - NCT00397111Recruiting
MRI brain-scanning study of mood and anxiety in adults
This study uses brain MRI scans and mental tasks to better understand mood and anxiety problems. It may help researchers develop improved MRI methods for studying depression and healthy brain function.
Bethesda, MarylandAges 18–65 - NCT07523490Recruiting
Understanding Suicide Risk in Mood Disorders
This research study aims to identify factors that increase suicide risk in people with mood disorders (like depression or bipolar disorder). By completing questionnaires, you'll help doctors better understand and prevent suicide in patients with these conditions.
Tianjin, Tianjin MunicipalityAges 16–60 - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT07389473Recruiting
Studying eye movements in long-term psychiatric medication use (Gaize device)
This trial uses a special device (Gaize) to track how your eyes move while you take psychiatric medication. It aims to see how long-term medication affects eye patterns, which could help doctors better understand treatment responses.
Philadelphia, PennsylvaniaAges 18–65 - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT06839950Recruiting
Sensory profiles and early signs in calm room users
This study looks at the sensory experiences of people newly admitted to a closed psychiatric unit who use a calm room. Researchers want to see if certain early signs or responses to the calm room differ based on a person's unique sensory profile.
Limoges, New AquitaineAges 18–65 - NCT06929442Recruiting
Prevention program for young adults with unusual experiences
This study tests a program to help young adults who have had unusual thoughts or experiences (like feeling people are talking about them or that things have hidden meanings) learn ways to cope and feel better. The goal is to prevent these experiences from turning into bigger problems.
Charlestown, MassachusettsAges 18–30 - NCT02443636Recruiting
Join a depression and mental health research registry in Atlantic Canada
This trial is a “registry,” meaning you can share your health information to help researchers study depression and other mental health needs in Atlantic Canada. Being part of the registry may help researchers understand patterns and improve future support and treatments.
Halifax, Nova ScotiaAges Any age - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT07211750Recruiting
Integrated care for older adults with depression and multiple health conditions
This trial tests a new integrated care program for older adults who have depression or bipolar disorder along with at least two other long-term physical health problems. The program aims to bring together your doctors and psychiatrist to improve your overall health.
LeuvenAges 65 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT06138054Recruiting
Mobile Program for Veterans with Mental Illness and Homelessness History
This trial tests a smartphone-based program to help veterans with serious mental illness who have experienced homelessness feel more connected to their community. It aims to see if the mobile coaching can improve daily living skills and reduce feelings of isolation.
West Los Angeles, CaliforniaAges 18–65 - NCT05832489RecruitingPhase 3
EEG-MRI test of methylphenidate in adult attention symptoms
This Phase 3 study tests how methylphenidate affects brain signals and attention in adults with ADHD, and in adults with mood-related attention problems. It also includes healthy volunteers to compare brain responses during brain scanning.
StrasbourgAges 18–60 - NCT06870006Recruiting
Heart monitoring for kids starting psychiatric drugs
This study is for children and teens in a hospital psychiatric ward who are starting a new medicine that might affect their heart's rhythm. It will check your heart with an ECG (electrocardiogram) to make sure it stays safe.
Troina, EnnaAges Up to 18 years
Hear when a new Mood Disorders trial opens
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Mood Disorders trials by city
Studies with a site in or near these metro areas.
Mood Disorders trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mood disorders?
- Yes. Clin2 currently lists 82 recruiting mood disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mood disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mood disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.