Clinical trials
Mouthwash clinical trials
Below are recruiting mouthwash clinical trials, each written for real people, not researchers. We’re tracking 38 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07069140Recruiting
Lactoferrin mouthwash for gum health during pregnancy
This study tests if a daily lactoferrin mouthwash can improve gum health in pregnant women with gum disease, without needing antibiotics or other treatments. Researchers want to see if this natural protein helps keep gums healthier during the second trimester.
Pavia, LombardyAges 18–45 - NCT06974604RecruitingPhase 2
Mouthwash to prevent mouth sores from Datopotamab deruxtecan
This trial tests if a dexamethasone mouthwash can prevent painful mouth sores (stomatitis) caused by the cancer drug Datopotamab deruxtecan (Dato-DXd). It's for people with certain types of advanced lung or breast cancer who have already tried other treatments.
Providence, Rhode IslandAges 18 years+ - NCT06920485Enrolling by invitation
Mouthwash after wisdom tooth surgery
This trial tests whether a mouthwash with hypochlorous acid can help healing after impacted wisdom tooth removal. It may reduce discomfort and speed recovery.
AnkaraAges 18–45 - NCT06900881RecruitingPhase 2/Phase 3
Kefir Mouthwash for Healthy Gums
This clinical trial tests if a mouthwash made from kefir, a fermented milk drink, can reduce gum swelling and bleeding (gingivitis) in young adults. You might benefit if you have mild gum disease but are otherwise healthy.
BaghdadAges 18–28 - NCT06824467RecruitingPhase 3
Maintenance Therapy Study for Recurrent Ovarian Cancer
This study tests a new maintenance treatment (sacituzumab tirumotecan) versus standard care for people with ovarian cancer that has come back after responding to platinum-based chemotherapy. The goal is to see if it can keep the cancer from growing longer and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT06714695Recruiting
Testing a mouthwash for black stains on kids' teeth
This trial tests if a special mouthwash made from chitosan (a natural substance from shellfish) can prevent black stains from coming back on children's teeth. Kids will use the mouthwash and be checked over 18 weeks to see if it works.
Cairo, Cairo GovernorateAges 6–12 - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT05319730RecruitingPhase 1/Phase 2
Testing new drugs, with or without pembrolizumab, for advanced esophageal cancer
This trial studies investigational cancer medicines, either alone or along with pembrolizumab, for people with advanced esophageal squamous cell cancer whose cancer has grown despite prior immune and platinum-based treatment. It may offer a new option after standard therapy has not worked.
Tucson, ArizonaAges 18 years+ - NCT04256798RecruitingPhase 3
Respiratory care after high-risk abdominal surgery
This trial looks at a breathing-focused care plan given around the time of major abdominal surgery to improve recovery and outcomes. You may be eligible if you’re having a large midline abdominal incision and can be followed after surgery.
Botucatu, São PauloAges 10–100 - NCT07696364Recruiting
Testing a mouthwash for gum health
This trial tests a special mouthwash (chlorhexidine) to see how well it prevents gum inflammation. It compares a standard version to one that also reduces tooth staining. You may be eligible if you are healthy, do not smoke, and have at least 24 teeth with healthy gums.
Bern, Canton of BernAges 18–40 - NCT07706647Recruiting
Oil pulling for gum health trial
This study tests if oil pulling (swishing oil in your mouth) can reduce gum inflammation and bleeding. It compares oil pulling to a standard mouthwash to see which is better for gum health.
San Antonio, TexasAges 18–70 - NCT07785609RecruitingPhase 2
New drug combination for advanced solid tumors
This trial tests a new drug combination for people with advanced solid tumors. It aims to see if the combination is safe and may shrink tumors.
San Antonio, TexasAges 18 years+ - NCT07810530RecruitingPhase 2
Mouthwash with laser for preventing mouth sores in stem cell transplant
This study tests whether a special mouthwash made from copaiba (a natural oil) plus low-level laser therapy can prevent mouth sores caused by high-dose chemotherapy before a stem cell transplant. It might help reduce pain and trouble eating during your transplant treatment.
Rio de Janeiro, Rio de JaneiroAges 12 years+ - NCT07619729Enrolling by invitationPhase 4
Oral Health Program for People With Type 2 Diabetes
This study tests whether a text-message and online program about caring for your teeth and gums can help people with type 2 diabetes. Researchers want to see if better oral health habits improve overall health outcomes.
Long Island City, New YorkAges 18 years+
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Common questions
- Are there clinical trials for mouthwash?
- Yes. Clin2 currently lists 38 recruiting mouthwash studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mouthwash trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mouthwash trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.