Clinical trials
Multiple Sclerosis Relapse clinical trials
Below are recruiting multiple sclerosis relapse clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07292480Recruiting
Monthly NfL monitoring for relapsing-remitting MS
This trial tests whether monthly blood tests for a nerve protein (NfL) can detect hidden disease activity in people with relapsing-remitting multiple sclerosis (RRMS) who are on certain first-line treatments. It aims to find out if this monitoring helps catch early signs of active disease before symptoms appear.
NiceAges 18–55 - NCT07303790RecruitingEarly Phase 1
Study of GC012F for people with multiple sclerosis
This early phase trial tests a new treatment called GC012F for people with multiple sclerosis. It aims to see how safe and tolerable it is, and may offer a new option for those whose current treatments are not working well enough.
Hubei, HubeiAges 18 years+ - NCT07318129Recruiting
Indole-3-propionic acid for multiple sclerosis
This trial tests an oral supplement called indole-3-propionic acid to see if it can help people with relapsing-remitting multiple sclerosis (RRMS). It involves taking the supplement daily and having regular MRI scans to monitor your MS.
Glostrup MunicipalityAges 18–65 - NCT07321093RecruitingPhase 3
A study of BCD-281 for relapsing-remitting MS
This trial tests a new medicine called BCD-281 for people with relapsing-remitting multiple sclerosis (RRMS). It aims to see if the drug can reduce relapses and improve disease control.
Nizhny NovgorodAges 18–55 - NCT07325292RecruitingPhase 3
Frexalimab injection vs IV for multiple sclerosis
This study tests if a new injection (frexalimab) works as well as the IV version for people with relapsing or certain types of secondary progressive multiple sclerosis. It could offer a more convenient way to receive this treatment at home.
Cullman, AlabamaAges 18–60 - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07497399RecruitingPhase 2
Testing a diabetes drug for weight loss in MS
This trial tests if a GLP-1 receptor agonist can help people with multiple sclerosis who have a high BMI. It may reduce inflammation and improve health.
Baltimore, MarylandAges 18–60 - NCT07353216Recruiting
Testing ofatumumab for relapsing multiple sclerosis
This trial tests if ofatumumab can help people with relapsing multiple sclerosis (RMS) by measuring its effect on nerve damage markers in the blood. It aims to see if the drug is safe and effective for controlling relapses and slowing disease activity.
Guangzhou, GuangdongAges 18 years+ - NCT07355387Recruiting
Home-based balance training for multiple sclerosis
This study tests a 12-week home-based balance training program for people with multiple sclerosis. Sessions are done online with a helper present, and the goal is to improve walking and reduce fall risk.
Chicago, IllinoisAges 40–90 - NCT07376772Recruiting
Wearable vibration therapy for arm and hand function in multiple sclerosis
This study tests if a wearable device that gently vibrates the arm can improve hand and arm function in people with multiple sclerosis. You would use the device at home while doing daily activities.
Gainesville, FloridaAges 18–100 - NCT07388992Recruiting
Walking patterns in people with MS
This study uses special sensors to compare walking patterns in people with multiple sclerosis (MS) and healthy volunteers. The goal is to see how MS affects walking over time, which may lead to better ways to track and treat movement problems.
LilleAges 18–65 - NCT07389590RecruitingPhase 4
Switching MS drugs for wearing-off symptoms
This study tests whether switching from ocrelizumab to a similar drug, ublituximab, can help people with MS who experience 'wearing-off' symptoms before their next infusion. It may offer a new option to keep symptoms more stable between doses.
Baltimore, MarylandAges 18–65 - NCT01703429Recruiting
Alternative care program for people with multiple sclerosis
This study looks at how a complementary or alternative care approach affects people living with multiple sclerosis. It may help to understand whether this type of program improves symptoms or quality of life over time.
Kenmore, WashingtonAges 18–100 - NCT07399262Recruiting
Music-based walking training for multiple sclerosis
This study tests whether walking to a steady beat of music can help improve your walking and balance. It is for people with mild to moderate multiple sclerosis who can walk but may need a little support.
Istanbul, ZeytinburnuAges 18–65 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT07438964Recruiting
Brain stimulation for MS fatigue
This study uses a safe, non-invasive brain stimulation technique to see if it can reduce fatigue in people with relapsing-remitting MS. It compares people with and without fatigue to understand how the brain is affected.
Berlin, State of BerlinAges 18–70 - NCT07477639RecruitingPhase 1/Phase 2
Testing TRX319 for worsening multiple sclerosis
This trial tests a new treatment called TRX319 for people with progressive multiple sclerosis (MS) that has been getting worse. The study wants to see if this treatment can help slow down disability progression.
Kansas City, KansasAges 18–65 - NCT07505355Recruiting
Walking and foot tap test in multiple sclerosis
This study tests two simple walking and foot-tapping exercises to see how well they measure balance and mobility in people with multiple sclerosis. It aims to help doctors better track walking problems in MS.
DiepenbeekAges 18–65 - NCT07507084Recruiting
Exercise with cognitive tasks for walking and balance in MS
This study combines exercise with a thinking activity to see if it improves walking, balance, and thinking skills in people with multiple sclerosis. It compares two types of exercise training to find which is more helpful for daily life.
Kütahya, MerkezAges 18–65 - NCT07510607RecruitingPhase 2
Metabolic imaging study for multiple sclerosis
This study tests a new imaging method using a special substance called hyperpolarized 13C pyruvate to see how it can help understand multiple sclerosis. You may join if you have relapsing-remitting MS, have not used disease-modifying treatments in the past two years, and are planning to start anti-CD20 therapy.
San Francisco, CaliforniaAges 18 years+ - NCT07536503Recruiting
How Sleep Quality Affects Thinking and Function in MS
This study looks at whether better sleep helps people with multiple sclerosis (MS) think more clearly and stay more physically active. Researchers will measure your sleep quality and test your memory and everyday abilities to see if they're connected.
Ankara, AnkaraAges 18–65 - NCT07549048Recruiting
Understanding caregiver stress in multiple sclerosis
This study asks patients with MS and their family caregivers about the emotional and physical strain of caregiving. By understanding caregiver burden, researchers hope to develop better support systems for families managing MS.
Istanbul, BahcelievlerAges 18–80 - NCT07614321RecruitingPhase 4
Silodosin for Bladder Symptoms in Women With MS
This study tests whether silodosin, a medication that relaxes bladder muscles, can help women with multiple sclerosis who have bothersome urinary symptoms. The goal is to see if it can reduce urgency, frequency, and other lower urinary tract problems.
Morristown, New JerseyAges 18 years+ - NCT07615725Recruiting
Dry Needling for Lower Leg Pain in Multiple Sclerosis
This study tests whether dry needling—a technique using thin needles to treat muscle pain—can help reduce lower leg pain in people with multiple sclerosis. Researchers want to see if this treatment can safely improve pain and function.
Tampa, FloridaAges 18–80
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Common questions
- Are there clinical trials for multiple sclerosis relapse?
- Yes. Clin2 currently lists 223 recruiting multiple sclerosis relapse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis relapse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis relapse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.