Clinical trials
Multiple Sclerosis Relapse clinical trials
Below are recruiting multiple sclerosis relapse clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07648277Recruiting
Spine Position, Movement, and Balance in Multiple Sclerosis
This study examines how multiple sclerosis affects your spine alignment, flexibility, and balance. Understanding these changes may help develop better physical therapies and support for people living with MS.
Ankara, ÇubukAges 18–65 - NCT07667322RecruitingPhase 1
Study of a new under-the-skin multiple sclerosis treatment
This trial tests a new way to give ocrelizumab, an approved MS treatment, as a shot under the skin instead of through an IV. It aims to see if it's safe and works well for people with relapsing or primary progressive MS.
Carlsbad, CaliforniaAges 18–65 - NCT07567989Enrolling by invitation
Home Exercise and Brain Stimulation for MS Fatigue
This study tests whether doing exercises at home combined with a non-invasive brain stimulation technique (gentle electrical stimulation on your scalp) can reduce the exhaustion and tiredness that comes with multiple sclerosis. The goal is to see if this combination helps you feel less fatigued and improves your ability to stay active.
A Coruña, A CoruñaAges 18–75 - NCT07074587Enrolling by invitation
Spinal stabilization exercise for MS-related bladder symptoms
This trial tests whether spinal stabilization exercises can improve bladder control and pelvic floor function in women with multiple sclerosis. If you have mild to moderate MS and bladder issues like urgency or leaking, this study may help you.
Merkez, BoluAges 18–65 - NCT06849960Enrolling by invitation
Reliability and validity of the Two-minute Test for Multiple Sclerosis
This study tests whether a simple two-minute walking test is a reliable way to measure function in people with multiple sclerosis. It aims to help doctors and patients understand the true value of this quick, easy test.
Şehitkamil, GaziantepAges 18–65 - NCT06495593Enrolling by invitationPhase 4
Ocrelizumab's effect on immune cells in lymph nodes in MS
This study tests how ocrelizumab, a medication for MS, affects immune cells in your lymph nodes. It may help doctors understand how the drug works and why it helps some people more than others.
San Francisco, CaliforniaAges 18–65 - NCT06223074Enrolling by invitationPhase 2
Nasal Steroid Spray for MS Relapses
This study tests a nasal spray form of the steroid methylprednisolone for treating MS relapses. The goal is to see if this new way of taking the medicine works as well or better than standard treatments.
Mexico CityAges 18–65 - NCT05706220Enrolling by invitation
Eye tests to measure visual speed in multiple sclerosis
This study tests how fast and how accurately your eyes process visual information and how eye movements look in people with multiple sclerosis. It may help researchers understand vision-related effects of MS using objective eye measurements.
Valladolid, ValladolidAges 18–80 - NCT04415372Enrolling by invitation
MRI brain scan study for white and gray matter in MS
This study uses detailed MRI scans to look at brain “white matter” and “gray matter” changes in people with multiple sclerosis (MS). It may help researchers better understand how MS affects the brain and relates to symptoms.
Madison, WisconsinAges 18–60 - NCT03032601Enrolling by invitation
N-acetyl cysteine study for people with multiple sclerosis
This study tests whether N-acetyl cysteine (a supplement-like medicine) changes body and brain function in people with multiple sclerosis. It may help researchers understand how it affects brain chemistry and activity using special brain imaging.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07503873RecruitingPhase 2
Study of ublituximab injection for multiple sclerosis
This trial tests a new way to give the drug ublituximab (an injection under the skin) to people with relapsing multiple sclerosis. It compares different injection sites and a special auto-injector device to see how the body absorbs the drug and if it's safe.
BihaćAges 18–65 - NCT04694534Recruiting
Serious game program to help thinking skills in multiple sclerosis
This trial tests whether a computer “serious game” can improve thinking and memory skills in people with multiple sclerosis (MS). It’s designed for adults who report thinking problems and show weaker-than-average results on specific brain tests.
Arras, Hauts-de-FranceAges 18–65 - NCT05811013Recruiting
Static magnetic brain stimulation for progressive multiple sclerosis
This trial studies whether a noninvasive brain stimulation approach using a static magnetic field can help people with progressive multiple sclerosis. It aims to improve progressive nerve function while keeping other treatments stable.
Pozzilli, IserniaAges 18–65 - NCT05835622Recruiting
Home walking brace study to improve quality of life in MS
This study tests whether using a home “walking exoskeleton” brace can improve quality of life for people with relapsing-remitting multiple sclerosis who have moderate walking problems. You would use the device at home, and the study team will check your walking safety and comfort during and after training.
Saint-Genis-Laval, Auvergne-Rhône-AlpesAges 18 years+ - NCT06270641Recruiting
Increasing physical activity for adults with MS
This study tests whether using a phone app (ExerciseRx) can help people with multiple sclerosis become more active. You may be able to join if you are not currently very active and can walk without needing a cane or walker.
Seattle, WashingtonAges 18 years+ - NCT06463743RecruitingPhase 2
Metformin for aging people with MS
This study tests whether metformin, a common diabetes drug, can help people with multiple sclerosis (MS) as they age. It may be used alone or added to your current MS treatment, and the goal is to see if it slows down aging-related changes in MS.
Buffalo, New YorkAges 55–75 - NCT06809192Recruiting
Cognitive behavioral therapy for multiple sclerosis fatigue
This study will test different parts of cognitive behavioral therapy to see which ones help with fatigue in people with multiple sclerosis. You will participate in sessions that may involve changing thoughts about fatigue, scheduling activities, or addressing related emotions like depression or anxiety.
Seattle, WashingtonAges 18 years+ - NCT06849882Recruiting
Balance test study for people with multiple sclerosis
This study will test whether a simple balance test (the Dubousset Functional Test) is reliable and accurate for people with MS. If you have mild disability and can stand without help, you may be able to join.
Kayseri, KayseriAges 18–65 - NCT06901687RecruitingPhase 2
Home brain stimulation for depression in MS
This study tests whether a special, gentle brain stimulation device you can use at home (called tDCS) can help improve depression symptoms in people with multiple sclerosis. You will be supervised over video during the sessions to make sure everything goes smoothly.
New York, New YorkAges 18–65 - NCT06964581Recruiting
At-home cognitive training for multiple sclerosis
This study tests a at-home thinking and memory training program for people with multiple sclerosis. It aims to help improve mental skills like memory, attention, and planning through remote sessions.
Verona, veronaAges 18–65 - NCT07011914Recruiting
MS care study for young adults
This study looks at how to improve care for young adults with relapsing-remitting MS. It focuses on people who are Black, Hispanic, or have limited income.
Birmingham, AlabamaAges 18 years+ - NCT02784210RecruitingPhase 2
Steroid treatment to reduce inflammation in active MS lesions
This Phase 2 study tests whether corticosteroid medicine can reduce inflammation at the edge of active multiple sclerosis (MS) plaques seen on MRI. It may help calm “hot” areas in the brain where MS activity is happening.
Bethesda, MarylandAges 18–120 - NCT07462338Enrolling by invitation
Walking test reliability in multiple sclerosis patients
This study checks how reliable a simple walking test (Timed Up and Go) is for people with multiple sclerosis, especially when they do another task at the same time. It aims to improve how doctors measure walking ability.
Gaziantep, GaziantepAges 18–65 - NCT06955962Enrolling by invitation
Mandala art therapy for multiple sclerosis symptoms and quality of life
This trial tests whether creating mandala art can help improve symptoms and quality of life for people with multiple sclerosis. You would participate in art sessions while continuing your regular MS care.
TrabzonAges 18–65
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Common questions
- Are there clinical trials for multiple sclerosis relapse?
- Yes. Clin2 currently lists 223 recruiting multiple sclerosis relapse studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis relapse trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis relapse trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.