Low-Oxygen Therapy for People With Multiple Sclerosis
Part of Brain & nervous system, Immune system & allergy clinical trials.
This study tests whether brief, controlled low-oxygen episodes (called intermittent hypoxia) can improve motor function in people with MS. It may help strengthen walking and daily movement.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have relapsing-remitting or secondary-progressive MS (a type that comes and goes or gets worse over time).
- Your disability level is between 3 and 6.5 on the EDSS scale (walking with some help, but not bedridden).
- You have not had an MS relapse (flare-up) in the last year.
- You are between 18 and 75 years old.
- You can safely have an MRI scan (no metal or devices that are not MRI-safe).
- If you take dalfampridine (Ampyra), you have been on the same dose for at least 2 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether breathing short bursts of reduced oxygen (acute intermittent hypoxia) can improve hand function and nerve health in people with relapsing-remitting MS who have some hand weakness.
This study tests whether brief periods of breathing air with lower oxygen levels can help people with different stages of multiple sclerosis (MS). It aims to see if this approach is safe and maybe beneficial.
This study combines brief periods of breathing slightly lower oxygen with walking practice to see if it helps improve walking in people with multiple sclerosis (MS). The goal is to see if this combined approach boosts the benefits of walking therapy.
This trial tests whether a special exercise method that briefly limits blood flow to the legs can improve strength and walking ability in people with multiple sclerosis (MS). If you have walking limitations, it may help you build fitness with less heavy resistance training—but you must be able to safely use a pressure cuff during testing.
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This study tests whether breathing lower-oxygen air in short breaks changes how the brain and body respond. It is only for medically stable, healthy adults with specific safety screening.
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