Low-Oxygen Therapy for People With Multiple Sclerosis
Part of Brain & nervous system, Immune system & allergy clinical trials.
This study tests whether brief, controlled low-oxygen episodes (called intermittent hypoxia) can improve motor function in people with MS. It may help strengthen walking and daily movement.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have relapsing-remitting or secondary-progressive MS (a type that comes and goes or gets worse over time).
- Your disability level is between 3 and 6.5 on the EDSS scale (walking with some help, but not bedridden).
- You have not had an MS relapse (flare-up) in the last year.
- You are between 18 and 75 years old.
- You can safely have an MRI scan (no metal or devices that are not MRI-safe).
- If you take dalfampridine (Ampyra), you have been on the same dose for at least 2 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether breathing short bursts of reduced oxygen (acute intermittent hypoxia) can improve hand function and nerve health in people with relapsing-remitting MS who have some hand weakness.
This study tests whether breathing low-oxygen air in short sessions might help people with MS at different disease stages. Researchers want to see if this approach is safe and might reduce symptoms or slow disease progression.
This study tests whether brief periods of reduced oxygen while walking can help improve walking ability and strength in people with multiple sclerosis. Researchers believe this approach may help retrain the nervous system to work better.
This trial tests whether high intensity exercise can improve both movement and thinking in people with multiple sclerosis. It might help if you can walk but need some support for balance.
This study tests if a non-invasive treatment called remote ischemic conditioning can help people with primary progressive multiple sclerosis. You wear a blood pressure cuff on your arm that briefly stops blood flow and then releases it, repeated for several cycles. The goal is to see if this improves walking and other functions.
This trial tests whether a special exercise method that briefly limits blood flow to the legs can improve strength and walking ability in people with multiple sclerosis (MS). If you have walking limitations, it may help you build fitness with less heavy resistance training—but you must be able to safely use a pressure cuff during testing.
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