Clinical trials · Philadelphia, PA
Multiple sclerosis clinical trials in Philadelphia
We’re tracking 10 recruiting multiple sclerosis studies with a site in or near Philadelphia — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06782490RecruitingPhase 2
Testing a new drug for MS muscle stiffness
This study tests an investigational drug (BMS-986368) to see if it helps reduce muscle stiffness and spasms caused by multiple sclerosis. It may be an option if you have had spasticity for at least 6 months and are not currently using other treatments that cannot be paused.
Philadelphia, PennsylvaniaAges 18–70 - NCT05285891RecruitingPhase 4
Stopping ocrelizumab in early relapsing multiple sclerosis
This study looks at whether people with early relapsing multiple sclerosis can safely stop ocrelizumab. Researchers will compare health and MRI findings over time to see if stopping helps or increases relapse risk.
Philadelphia, PennsylvaniaAges 18–55 - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04047628RecruitingPhase 3
MS patients with active relapsing disease comparing two treatment plans
This Phase 3 study compares the best standard MS treatment (chosen by your doctors) versus an approach called autologous hematopoietic stem cell transplant (AHSCT) for people with highly active, treatment-resistant relapsing multiple sclerosis. It aims to see which option controls MS disease activity better and keeps you safer over time.
Philadelphia, PennsylvaniaAges 18–55 - NCT05162638Enrolling by invitation
Immune study in MS and healthy adults using a special tube
This study compares immune (defense system) “profiles” between people with multiple sclerosis (MS) and healthy volunteers. It involves a thoracic duct cannulation procedure and several MRIs to see how immune cells behave and whether a specific immune pattern is different in MS.
Philadelphia, PennsylvaniaAges 18–40 - NCT07424027Recruiting
Central vein sign in multiple sclerosis extension study
This study is for people already in the CAVS-MS study. It uses MRI scans to look at a specific sign in the brain that may help diagnose multiple sclerosis.
Philadelphia, PennsylvaniaAges 18–65 - NCT03032601Enrolling by invitation
N-acetyl cysteine study for people with multiple sclerosis
This study tests whether N-acetyl cysteine (a supplement-like medicine) changes body and brain function in people with multiple sclerosis. It may help researchers understand how it affects brain chemistry and activity using special brain imaging.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07415824Recruiting
Multiple Sclerosis Registry Study
This study creates a registry for people with multiple sclerosis (MS) to track their health over time. The information gathered may help researchers better understand MS and improve care.
Cherry Hill, New JerseyAges 18 years+ - NCT06433752Recruiting
Study of BRIUMVI for relapsing multiple sclerosis
This study looks at how well BRIUMVI (a medicine for relapsing multiple sclerosis) works for people in everyday life. Researchers want to see how people do when they first start the medication.
Cherry Hill, New JerseyAges 18 years+ - NCT07732907Recruiting
Study of PML risk in MS patients taking Zeposia
This study looks at people with multiple sclerosis who have taken Zeposia (ozanimod) and later developed a rare brain infection called PML. The goal is to understand how often this happens and to confirm cases.
Lawrenceville, New JerseyAges Any age
Hear when a new Multiple sclerosis trial opens near Philadelphia, PA
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Multiple sclerosis trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting multiple sclerosis studies listed above.
- University of Pennsylvania · 4 studies
- Thomas Jefferson University Hospital · 3 studies
- Bristol Myers Squibb
- Multiple Sclerosis Association of America
- TG Therapeutics Investigational Trial Site
What taking part in a multiple sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting multiple sclerosis studies in Pennsylvania.
Common questions
- Are there multiple sclerosis clinical trials near Philadelphia?
- Yes. We're currently tracking 10 recruiting multiple sclerosis studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a multiple sclerosis study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New multiple sclerosis studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.