Testing a new drug for MS muscle stiffness
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Immune system & allergy clinical trials.
This study tests an investigational drug (BMS-986368) to see if it helps reduce muscle stiffness and spasms caused by multiple sclerosis. It may be an option if you have had spasticity for at least 6 months and are not currently using other treatments that cannot be paused.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with multiple sclerosis (MS).
- You have had muscle stiffness or spasms (spasticity) from MS for at least 6 months.
- Your muscle stiffness is moderate to severe in at least two muscle groups (including at least one in your leg, but not your ankle).
- Your level of disability is moderate to severe (EDSS score between 3.0 and 6.5).
- You are not taking other spasticity medicines that can't be stopped before the study starts, and you haven't used cannabis or CBD in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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