Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 428 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07648277Recruiting
Spine Position, Movement, and Balance in Multiple Sclerosis
This study examines how multiple sclerosis affects your spine alignment, flexibility, and balance. Understanding these changes may help develop better physical therapies and support for people living with MS.
Ankara, ÇubukAges 18–65 - NCT06681623Recruiting
Ublituximab in older adults with relapsing MS
This study is testing how safe and effective the medication ublituximab is for older adults (ages 55–80) with relapsing multiple sclerosis. It aims to see if this treatment works well for this age group.
Foxborough, MassachusettsAges 55–80 - NCT07630311Recruiting
Balance and walking study in multiple sclerosis
This study looks at how multiple sclerosis affects balance, walking patterns, and movement. Researchers will use motion analysis to understand changes, which could help improve treatments.
IoanninaAges 18 years+ - NCT07635693Recruiting
ATLG Levels During Stem Cell Transplant for Multiple Sclerosis
This study measures how a specific immune-suppressing medication (ATLG) works in patients with multiple sclerosis who are undergoing autologous stem cell transplantation—a procedure where your own blood stem cells are removed, treated, and returned to help reset your immune system.
Milan, ItalyAges 18 years+ - NCT06389968Recruiting
Light therapy for vision after optic neuritis in MS
This study tests whether light stimulation can help improve vision after optic neuritis in people with multiple sclerosis. It may offer a way to support eye recovery without medication.
Munich, BavariaAges 18–60 - NCT07615725Recruiting
Dry Needling for Lower Leg Pain in Multiple Sclerosis
This study tests whether dry needling—a technique using thin needles to treat muscle pain—can help reduce lower leg pain in people with multiple sclerosis. Researchers want to see if this treatment can safely improve pain and function.
Tampa, FloridaAges 18–80 - NCT07614321RecruitingPhase 4
Silodosin for Bladder Symptoms in Women With MS
This study tests whether silodosin, a medication that relaxes bladder muscles, can help women with multiple sclerosis who have bothersome urinary symptoms. The goal is to see if it can reduce urgency, frequency, and other lower urinary tract problems.
Morristown, New JerseyAges 18 years+ - NCT07606742Recruiting
Exercise Training for Hispanics With Multiple Sclerosis
This study tests a culturally tailored exercise program designed specifically for Hispanic people with multiple sclerosis (MS) who have walking difficulties. The goal is to help improve walking ability and overall quality of life through a personalized exercise plan.
Houston, TexasAges 18 years+ - NCT06461741Recruiting
EMG biofeedback training for balance in MS
This study tests whether a special training method that uses muscle signals (called EMG biofeedback) can help people with MS improve their walking and balance. If you have problems with walking or balance and your MS is stable, you may be able to join.
Hamilton, OntarioAges 18–80 - NCT07587125RecruitingPhase 1
CAR-T Cell Therapy for Progressive Multiple Sclerosis
This trial tests a new cell therapy called S103 for people with MS that isn't responding well to standard treatments. The therapy involves modifying immune cells in the lab and putting them back into your body to help control the disease.
Xi'an, ShaanxiAges 18–75 - NCT06728956Recruiting
Online resilience training to help people with MS keep their jobs
This trial tests an online program based on Acceptance and Commitment Therapy (ACT) to build resilience and prevent job loss in people with multiple sclerosis (MS) and in healthcare workers who treat MS patients. The study will see if the program helps you stay at work and feel better.
LeedsAges 18–66 - NCT06374108Recruiting
Resistance training and walking in multiple sclerosis
This study tests whether resistance training (like lifting weights) can improve how your brain and muscles communicate, and whether that helps your walking. It's designed for people with MS who have some walking difficulties.
Aarhus, Central JutlandAges 18 years+ - NCT05092191RecruitingPhase 2
Cannabis pill study for MS-related muscle stiffness
This Phase 2 trial tests whether cannabis can reduce muscle stiffness (spasticity) in people with multiple sclerosis. You may be able to participate if your stiffness is not improving with your current treatments.
Montreal, QuebecAges 21 years+ - NCT05177523Recruiting
MRI study of nerve damage and repair in multiple sclerosis
This trial uses MRI scans to better understand how nerve fibers are damaged and repaired in people with multiple sclerosis. It may help researchers connect scan findings to disease activity and progression.
BaselAges 18–80 - NCT07567989Enrolling by invitation
Home Exercise and Brain Stimulation for MS Fatigue
This study tests whether doing exercises at home combined with a non-invasive brain stimulation technique (gentle electrical stimulation on your scalp) can reduce the exhaustion and tiredness that comes with multiple sclerosis. The goal is to see if this combination helps you feel less fatigued and improves your ability to stay active.
A Coruña, A CoruñaAges 18–75 - NCT07549048Recruiting
Understanding caregiver stress in multiple sclerosis
This study asks patients with MS and their family caregivers about the emotional and physical strain of caregiving. By understanding caregiver burden, researchers hope to develop better support systems for families managing MS.
Istanbul, BahcelievlerAges 18–80 - NCT07544303Recruiting
Fatigue and Mental Well-Being in MS Patients
This study explores how fatigue and mental health are connected in people with multiple sclerosis. Researchers will use audio sessions through headphones to understand your experiences and may help improve care for MS-related tiredness and mood.
VanAges 18–80 - NCT07536503Recruiting
How Sleep Quality Affects Thinking and Function in MS
This study looks at whether better sleep helps people with multiple sclerosis (MS) think more clearly and stay more physically active. Researchers will measure your sleep quality and test your memory and everyday abilities to see if they're connected.
Ankara, AnkaraAges 18–65 - NCT07510607RecruitingPhase 2
Metabolic imaging study for multiple sclerosis
This study tests a new imaging method using a special substance called hyperpolarized 13C pyruvate to see how it can help understand multiple sclerosis. You may join if you have relapsing-remitting MS, have not used disease-modifying treatments in the past two years, and are planning to start anti-CD20 therapy.
San Francisco, CaliforniaAges 18 years+ - NCT07505355Recruiting
Walking and foot tap test in multiple sclerosis
This study tests two simple walking and foot-tapping exercises to see how well they measure balance and mobility in people with multiple sclerosis. It aims to help doctors better track walking problems in MS.
DiepenbeekAges 18–65 - NCT07507084Recruiting
Exercise with cognitive tasks for walking and balance in MS
This study combines exercise with a thinking activity to see if it improves walking, balance, and thinking skills in people with multiple sclerosis. It compares two types of exercise training to find which is more helpful for daily life.
Kütahya, MerkezAges 18–65 - NCT07504120Recruiting
Home Pilates for people with multiple sclerosis
This study tests whether doing Pilates exercises from home, through online video sessions, can improve physical and mental well-being in people with mild to moderate multiple sclerosis. If you are fairly mobile and not very active, this could be a gentle way to increase exercise and feel better.
Chicago, IllinoisAges 18 years+ - NCT07492667Recruiting
Comparing new vs. old criteria for diagnosing multiple sclerosis
This trial compares two sets of diagnostic criteria (McDonald criteria 2024 vs. 2017) for multiple sclerosis in real-life settings. It aims to see which criteria work better in diagnosing MS in patients with symptoms or MRI findings that suggest the disease.
Ars-Laquenexy, LorraineAges Any age - NCT07489794Recruiting
Bladder Control and Pelvic Floor in MS
This study looks at how multiple sclerosis (MS) affects bladder control and pelvic floor muscles. It may help find better ways to manage urinary incontinence (leaking urine) in women with MS.
IstanbulAges 30–50
Hear when a new Multiple sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 428 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.