Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 428 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07492667Recruiting
Comparing new vs. old criteria for diagnosing multiple sclerosis
This trial compares two sets of diagnostic criteria (McDonald criteria 2024 vs. 2017) for multiple sclerosis in real-life settings. It aims to see which criteria work better in diagnosing MS in patients with symptoms or MRI findings that suggest the disease.
Ars-Laquenexy, LorraineAges Any age - NCT07477639RecruitingPhase 1/Phase 2
Testing TRX319 for worsening multiple sclerosis
This trial tests a new treatment called TRX319 for people with progressive multiple sclerosis (MS) that has been getting worse. The study wants to see if this treatment can help slow down disability progression.
La Jolla, CaliforniaAges 18–65 - NCT07475377Recruiting
Meal timing and brain health in multiple sclerosis
This study looks at whether changing when you eat during the day can improve brain health for people with multiple sclerosis. It involves following a specific eating schedule and using a smartphone to track your meals.
Birmingham, AlabamaAges 18–64 - NCT07466823Recruiting
Spasticity Patterns and Quality of Life in MS
This study looks at patterns of muscle stiffness (spasticity) in people with multiple sclerosis and how these patterns affect daily life and well-being. It aims to better understand the link between spasticity and quality of life.
IstanbulAges 18 years+ - NCT07438964Recruiting
Brain stimulation for MS fatigue
This study uses a safe, non-invasive brain stimulation technique to see if it can reduce fatigue in people with relapsing-remitting MS. It compares people with and without fatigue to understand how the brain is affected.
Berlin, State of BerlinAges 18–70 - NCT07444047Recruiting
MRI study of brain lesions in older MS patients
This study uses MRI scans to compare brain lesions in older patients with multiple sclerosis versus those with small vessel disease. It aims to improve how doctors tell apart these conditions and may lead to better treatment choices.
Oslo, OsloAges 50–80 - NCT07426991Recruiting
Multiple sclerosis, thinking, sleep, and tiredness study
This study looks at how multiple sclerosis (MS) affects your thinking, sleep, and tiredness. It compares people with MS who have at least mild fatigue to people without MS who also have sleep problems, to understand these issues better.
DüsseldorfAges 18–79 - NCT06723444Recruiting
Improving Memory in Portuguese Patients with Multiple Sclerosis
This study tests a new method to improve memory and learning in people with multiple sclerosis who have mild memory problems. You'll undergo memory training and assessments to see if it helps.
PortoAges 18–70 - NCT07399262Recruiting
Music-based walking training for multiple sclerosis
This study tests whether walking to a steady beat of music can help improve your walking and balance. It is for people with mild to moderate multiple sclerosis who can walk but may need a little support.
Istanbul, ZeytinburnuAges 18–65 - NCT06827834Recruiting
Spinal cord monitoring for multiple sclerosis
This trial uses MRI scans to monitor spinal cord changes in people newly diagnosed with relapsing-remitting MS who have not yet started treatment. It aims to better understand how the disease progresses and could help guide early treatment decisions.
Arnhem, GelderlandAges 18–65 - NCT07389590RecruitingPhase 4
Switching MS drugs for wearing-off symptoms
This study tests whether switching from ocrelizumab to a similar drug, ublituximab, can help people with MS who experience 'wearing-off' symptoms before their next infusion. It may offer a new option to keep symptoms more stable between doses.
Baltimore, MarylandAges 18–65 - NCT02486562Recruiting
Research network for people with multiple sclerosis
This study builds a patient-powered research network for people living with multiple sclerosis. It may help by gathering real-world information from patients to improve understanding of the disease over time.
Waltham, MassachusettsAges Any age - NCT02912897RecruitingPhase 1
EBV T-cell treatment for early multiple sclerosis-like symptoms
This early-phase study tests whether a patient’s own immune cells (made to target a common virus called EBV) are safe and practical for people who have their first episode that strongly suggests multiple sclerosis. If it works well, it could offer a new way to treat early disease—but the main goal now is safety and feasibility.
NantesAges 18–45 - NCT07388992Recruiting
Walking patterns in people with MS
This study uses special sensors to compare walking patterns in people with multiple sclerosis (MS) and healthy volunteers. The goal is to see how MS affects walking over time, which may lead to better ways to track and treat movement problems.
LilleAges 18–65 - NCT06845722Recruiting
Balance and cognitive training for multiple sclerosis
This trial tests whether combining balance exercises with brain-training activities can help improve walking and thinking in people with multiple sclerosis. It is for people aged 40–55 who have mild cognitive problems and balance issues.
LahoreAges 40–55 - NCT07355387Recruiting
Home-based balance training for multiple sclerosis
This study tests a 12-week home-based balance training program for people with multiple sclerosis. Sessions are done online with a helper present, and the goal is to improve walking and reduce fall risk.
Chicago, IllinoisAges 40–90 - NCT07346703Enrolling by invitation
DHA supplement study for multiple sclerosis patients
This trial tests whether taking a DHA supplement (a type of omega-3 fat) can help people with multiple sclerosis. It aims to see if it may improve muscle function or overall well-being.
La Ñora, MurciaAges 18–65 - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07325292RecruitingPhase 3
Frexalimab injection vs IV for multiple sclerosis
This study tests if a new injection (frexalimab) works as well as the IV version for people with relapsing or certain types of secondary progressive multiple sclerosis. It could offer a more convenient way to receive this treatment at home.
Cullman, AlabamaAges 18–60 - NCT07303790RecruitingEarly Phase 1
Study of GC012F for people with multiple sclerosis
This early phase trial tests a new treatment called GC012F for people with multiple sclerosis. It aims to see how safe and tolerable it is, and may offer a new option for those whose current treatments are not working well enough.
Hubei, HubeiAges 18 years+ - NCT06016309Recruiting
Understanding Thinking, Energy, Mood, and Behavior in MS
This study looks at how multiple sclerosis affects thinking, energy, mood, and behavior. It uses simple tests and questionnaires to understand your unique profile, which may help tailor future care.
Groningen, Provincie GroningenAges 18–70 - NCT07252895Recruiting
Testing the EXOPULSE Suit for walking in multiple sclerosis
This trial tests whether the EXOPULSE Suit can help people with multiple sclerosis walk better. You will try the suit and we will measure how it affects your walking over time.
BerckAges 18 years+ - NCT06068582Recruiting
Keep your memory sharp and stay at work with MS
This study tests a program of physical and mental exercises designed to slow down memory and thinking problems in people with multiple sclerosis, and help them stay employed longer.
AmsterdamAges 18–67 - NCT07222618Recruiting
Selfie videos to measure function in MS
This trial asks people with MS to record short 'selfie' videos of themselves doing everyday tasks, like walking or getting dressed. The goal is to find a better, more personal way to measure how MS affects daily function.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 428 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.