Clinical trials
Narcolepsy Type 2 clinical trials
Below are recruiting narcolepsy type 2 clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07598708RecruitingPhase 2/Phase 3
Cleminorexton for Narcolepsy: A New Treatment Study
This study tests whether a new medication called cleminorexton helps people with narcolepsy (a condition causing severe daytime sleepiness) sleep better and feel more alert. You would take this medication instead of your current narcolepsy drugs for several months to see if it works.
Colorado Springs, ColoradoAges 18–70 - NCT07502443RecruitingPhase 3
Study of ALKS 2680 for narcolepsy type 2
This study tests an investigational drug called ALKS 2680 for people with narcolepsy type 2, a condition that causes excessive daytime sleepiness without sudden muscle weakness. The goal is to see if the drug is safe and helps reduce daytime sleepiness.
Cullman, AlabamaAges 18–70 - NCT06767683RecruitingPhase 2/Phase 3
Long-term study of ALKS 2680 for narcolepsy and idiopathic hypersomnia
This study is for people with narcolepsy or idiopathic hypersomnia who have already taken part in an earlier ALKS 2680 study. It aims to see how well the medication works and how safe it is when taken for a longer time.
Cullman, AlabamaAges 18–70 - NCT07455383RecruitingPhase 3
Testing ALKS 2680 for adults with narcolepsy type 1
This study tests a new medication, ALKS 2680, to see if it helps reduce daytime sleepiness and other symptoms in adults with narcolepsy type 1. It may offer a new treatment option for people with this condition.
Cullman, AlabamaAges 18–70 - NCT06952699RecruitingPhase 2
TAK-360 for narcolepsy type 2
This study tests a new medicine called TAK-360 for people with narcolepsy type 2 (narcolepsy without cataplexy). It aims to see if the drug safely reduces daytime sleepiness.
Auburn, AlabamaAges 18–70 - NCT07299097Recruiting
Narcolepsy type 1 and type 2 study in Spain
This study looks at people with narcolepsy type 1 or type 2 in Spain to learn more about these conditions. If you or your child has a confirmed diagnosis, you may be able to take part.
Castellon, CastellonAges birth+ - NCT06383806Recruiting
Reducing nightmares in adults with narcolepsy
This study tests a new behavioral treatment to reduce nightmares in adults with narcolepsy. It aims to help you sleep better and feel more rested.
Salt Lake City, UtahAges 18 years+ - NCT05773872Recruiting
Testing social understanding in narcolepsy and hypersomnia
This study compares “social cognition” (how people recognize and understand others’ thoughts and feelings) in adults with narcolepsy or idiopathic hypersomnia. It may help researchers better understand how these conditions can affect everyday social interactions.
AmiensAges 18 years+ - NCT06752668RecruitingPhase 2
Testing ORX750 for narcolepsy and idiopathic hypersomnia
This trial tests an experimental drug called ORX750 for people with narcolepsy or idiopathic hypersomnia. You would need to stop your current sleepiness medicines to see if ORX750 helps reduce daytime sleepiness.
Auburn, AlabamaAges 18–65 - NCT07006233Recruiting
Dietary change study for narcolepsy and hypersomnia
This study tests whether changing your diet to include more animal protein and fat (like a low-carb diet) can improve symptoms of narcolepsy or idiopathic hypersomnia. You'll need to check your ketone levels at home and be willing to make lasting dietary changes.
Macquarie Park, New South WalesAges 18 years+ - NCT07096674RecruitingPhase 2
Long-term study of ORX750 for narcolepsy and idiopathic hypersomnia
This trial is for people who have already completed the main CRYSTAL-1 study of ORX750. It tests the long-term safety and effects of the drug, so you can continue treatment if it was helping you.
Auburn, AlabamaAges 18–65 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT07646678RecruitingPhase 2/Phase 3
TAK-360 Extension Study for Narcolepsy or Excessive Sleepiness
This is a follow-up study for people who already completed a TAK-360 trial for narcolepsy (a sleep disorder causing sudden sleep attacks) or idiopathic hypersomnia (excessive daytime sleepiness). Researchers want to see if continuing TAK-360 remains safe and effective for you.
Shinjuku-ku, TokyoAges 18–71 - NCT07633301RecruitingPhase 2
TAK-360 Study for Adults With Narcolepsy Type 1
This study tests a new medication called TAK-360 to help adults with narcolepsy type 1 (a condition that causes extreme daytime sleepiness and sudden muscle weakness called cataplexy) feel more alert during the day. The goal is to see if this treatment is safe and effective for managing narcolepsy symptoms.
Redwood City, CaliforniaAges 18–70 - NCT05208164Recruiting
Mindfulness program for Black adults with type 2 diabetes
This study tests whether a mindfulness class, delivered by text messages and online or in-person sessions, can help adults with type 2 diabetes. It is designed specifically for African American/Black participants in the Chicago area.
Chicago, IllinoisAges 21–75 - NCT07540897RecruitingPhase 3
Testing ALKS 2680 for narcolepsy type 1
This study tests whether a new medication called ALKS 2680 can help people with narcolepsy type 1 stay more awake and alert during the day. Narcolepsy type 1 is a neurological condition where people fall asleep unexpectedly and may experience sudden muscle weakness.
Miami, FloridaAges 18–70 - NCT06471634Recruiting
Improving sleep and reducing sitting time in type 2 diabetes
This study tests whether a program to improve sleep and reduce sitting time can help people with type 2 diabetes. It combines cognitive behavioral therapy for insomnia with tips to move more during the day.
Leicester, LeicestershireAges 18–75 - NCT07363720RecruitingPhase 3
A study of TAK-861 for narcolepsy with cataplexy
This trial tests a new medication called TAK-861 for people with narcolepsy type 1 (NT1), which causes sudden muscle weakness (cataplexy) and extreme daytime sleepiness. The study aims to see if TAK-861 can help reduce these symptoms.
Redwood City, CaliforniaAges 16–70 - NCT05816382RecruitingPhase 2/Phase 3
Testing TAK-861 for narcolepsy type 1 sleepiness
This Phase 2/3 study tests TAK-861 in people with narcolepsy type 1 (NT1) who already completed an earlier TAK-861 trial. The goal is to see if the medicine remains safe and effective for ongoing central (brain-related) sleepiness problems.
Birmingham, AlabamaAges 16–70 - NCT06809803RecruitingPhase 2
Extended-release sodium oxybate for children with narcolepsy
This trial tests an extended-release medicine (sodium oxybate) to see if it helps children with narcolepsy type 1 feel less sleepy during the day. It is only for children who are seen at the Stanford Sleep Clinic and have a clear diagnosis.
Redwood City, CaliforniaAges 7–17
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Narcolepsy Type 2 trials by city
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Narcolepsy Type 2 trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for narcolepsy type 2?
- Yes. Clin2 currently lists 20 recruiting narcolepsy type 2 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a narcolepsy type 2 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a narcolepsy type 2 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.