Clinical trials
Narcolepsy clinical trials
Below are recruiting narcolepsy clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05773872Recruiting
Testing social understanding in narcolepsy and hypersomnia
This study compares “social cognition” (how people recognize and understand others’ thoughts and feelings) in adults with narcolepsy or idiopathic hypersomnia. It may help researchers better understand how these conditions can affect everyday social interactions.
AmiensAges 18 years+ - NCT05321355Recruiting
Sleep disorder patient registry for narcolepsy and other conditions
This is a research registry that collects information from people with narcolepsy and other neurological sleep disorders. It may help doctors better understand sleep problems and improve future care.
Mainz, Rhineland-PalatinateAges 18–120 - NCT07584434RecruitingPhase 1
Safety and Dosage Study of VX-433 in Healthy People
This is a first-in-human study testing a new drug called VX-433 to see how safe it is and how the body handles it. Vertex Pharmaceuticals is running this early-stage trial to understand the right dosage and side effects in healthy volunteers.
Salt Lake City, UtahAges 18–55 - NCT06797284Recruiting
Light, electrical, and magnetic therapy for sleep issues
This study tests if light, electrical, or magnetic treatments can help people with insomnia, narcolepsy, or REM sleep behavior disorder improve their sleep-wake problems. It compares these gentle brain stimulation methods to understand which works best.
Suzhou, JiangsuAges 8–75 - NCT07365566Recruiting
Pain and sleep behavior disorder study
This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.
ToulouseAges 18 years+ - NCT06809803RecruitingPhase 2
Extended-release sodium oxybate for children with narcolepsy
This trial tests an extended-release medicine (sodium oxybate) to see if it helps children with narcolepsy type 1 feel less sleepy during the day. It is only for children who are seen at the Stanford Sleep Clinic and have a clear diagnosis.
Redwood City, CaliforniaAges 7–17 - NCT06413420Recruiting
Pregnancy registry for narcolepsy or sleep apnea treatments
This study tracks the health of pregnant women who have narcolepsy or sleep apnea, or who have taken certain wake-promoting medications during pregnancy. It helps researchers learn more about the safety of these treatments for mothers and babies.
Morrisville, North CarolinaAges Any age - NCT05816382RecruitingPhase 2/Phase 3
Testing TAK-861 for narcolepsy type 1 sleepiness
This Phase 2/3 study tests TAK-861 in people with narcolepsy type 1 (NT1) who already completed an earlier TAK-861 trial. The goal is to see if the medicine remains safe and effective for ongoing central (brain-related) sleepiness problems.
Birmingham, AlabamaAges 16–70 - NCT05536011Recruiting
Pregnancy registry for women taking WAKIX (pitolisant)
This registry collects information about pregnancy outcomes in women who took WAKIX (pitolisant) or a similar comparison medicine during pregnancy. It helps doctors understand the safety and effects of these medicines in pregnancy.
Morrisville, North CarolinaAges Any age - NCT05371483Enrolling by invitation
Study effects of narcolepsy and hypersomnia treatments on brain and heart
This study looks at how narcolepsy or idiopathic hypersomnia affects thinking and cardiovascular health, and how usual treatment medications may change those outcomes. It may help researchers understand risks and benefits of common hypersomnia therapies.
Scottsdale, ArizonaAges 18–75 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
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Common questions
- Are there clinical trials for narcolepsy?
- Yes. Clin2 currently lists 35 recruiting narcolepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a narcolepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a narcolepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.