Clinical trials
Ophthalmology clinical trials
Below are recruiting ophthalmology clinical trials, each written for real people, not researchers. We’re tracking 45 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03811964Recruiting
Test how light affects your sleep, mood, nerves, and vision
This study uses a light-based test (the “photomotor reflex”) to see how non-visual effects of light may affect sleep-wake timing, brain function, mental health, and eyesight. You may be assigned to a group based on your condition, or you may be in the healthy control group.
StrasbourgAges 18 years+ - NCT07063719Recruiting
Finding cell markers for rare eye diseases in adults
This study looks for biological markers in the blood or eye samples of people with rare eye diseases compared to healthy volunteers. It aims to better understand and diagnose these conditions.
ParisAges 18 years+ - NCT07019558Recruiting
Eye disorders in dominant spinal-cerebellar ataxias
This trial looks for eye problems in people with certain genetic forms of spinocerebellar ataxia (SCA1, SCA2, SCA3, or SCA27B). You have to be between 18 and 80 years old and have a specific genetic mutation. You can join if you already have symptoms or if you are at risk but do not have symptoms yet.
Montpellier, HéraultAges 18–80 - NCT02485847Recruiting
Join an eye health research registry
This trial is a research registry that collects information from people who are getting eye care. It helps researchers better understand eye disease and outcomes over time, which may improve future care.
San Francisco, CaliforniaAges 6 months+ - NCT07566975Recruiting
How VEVYE Helps Dry Eye in Neuro-Eye Patients
This study tracks whether VEVYE®, a prescription eye drop, reduces dry eye symptoms and signs in people who have both a neuro-ophthalmic condition (a nerve or brain issue affecting the eyes) and dry eye disease. You'll visit the clinic for 6 months and answer questions about your eye comfort.
Houston, TexasAges 18 years+ - NCT07771998Recruiting
Skin and eye tolerance test for sensitive skin
This study tests a product on women with sensitive skin to see if it causes any skin or eye irritation. It helps find out if the product is safe and gentle for daily use.
Osasco, São PauloAges 18–60 - NCT05847894Recruiting
AI eye scans to help diagnose lung breathing problems
This trial tests an artificial intelligence (AI) tool that uses eye images to help doctors diagnose breathing or lung-related conditions. If you have a lung/breathing problem and can do both eye and lung checkups, it may support faster or more accurate diagnosis.
Guangzhou, GuangdongAges Any age - NCT06043622Recruiting
Healthy eye blood vessel database study
This study uses a special eye scan (OCT angiography) to create a reference database of normal blood vessels in healthy eyes. It helps doctors compare and diagnose eye conditions later.
AmiensAges 18 years+ - NCT06859216Recruiting
Testing AI-made plain language summaries for eye clinic notes
This study tests whether using artificial intelligence (AI) to create easy-to-read summaries of your eye doctor's notes helps people better understand their eye care. If you are an English-speaking patient at the Jules Stein Eye Institute, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT06752486RecruitingPhase 1
Gabapentin for pain after laser eye surgery
This study tests if a medicine called gabapentin can safely reduce pain after a type of laser eye surgery called surface ablation. It's looking for adults with stable vision who are generally healthy and have not had previous eye procedures.
GizaAges 18–65 - NCT04959838Recruiting
Study of job stress in eye doctors and trainees
This study looks at job stress among ophthalmologists (eye doctors) and ophthalmology residents. It may help improve working conditions and support for people in eye care.
Clermont-FerrandAges 18–65 - NCT07174141Recruiting
Heart risks from newer blood cancer drugs (acalabrutinib or zanubrutinib)
This study looks for early signs of heart problems in people taking newer targeted blood cancer drugs called acalabrutinib or zanubrutinib. By using special blood tests, doctors hope to catch and manage heart issues before they become serious.
DijonAges 18 years+ - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+ - NCT04451265Recruiting
MRI test study for suspected anterior optic nerve stroke
This study checks how well a special MRI scan (diffusion-weighted imaging) can identify a specific optic nerve problem called anterior ischemic optic neuropathy (when blood flow to the optic nerve is reduced). If you have symptoms that suggest this condition, the trial compares your MRI findings to doctors’ assessment to see if the scan helps confirm the diagnosis.
Lille, LilleAges 18 years+ - NCT03381794Recruiting
Cornea transplant registry for patients in Germany
This trial is not testing a new treatment. It collects and organizes information about people in Germany who have had a corneal (front-of-eye) transplant since 2001 to help future care and research.
Homburg, SaarlandAges 1–100 - NCT07258212Recruiting
Safety and normal vision data study with Neos device
This study is testing a device called Neos to gather safety information and normal vision data. It includes both healthy volunteers and people with eye or brain conditions, helping researchers understand how vision and eye movements work.
Bern, Canton of BernAges 3 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT07742878Recruiting
Vision testing in people with recent brain injury
This study tests a new device called the Traq™ that looks at how well the two eyes work together. It's for people with a recent mild-to-moderate brain injury and for people without one, to see if the device can spot vision changes after injury.
Waukee, IowaAges 12 years+ - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT04389437Recruiting
Eye imaging study for people with memory problems
This study uses detailed eye scans to look for changes that might relate to memory problems. You may be able to join if you are being seen for memory concerns and meet the health and eye-scan requirements.
ParisAges 18 years+ - NCT04681417RecruitingPhase 2/Phase 3
Eye-sparing treatment options for children with retinoblastoma
This trial studies whether newer “save-the-eye” treatment plans can control retinoblastoma (eye cancer) while keeping vision as good as possible. It compares different conservative treatment strategies depending on how the tumor looks and where it is.
Saint-Denis, La RéunionAges 6 months–6 years - NCT05264818Recruiting
Study measures eye surface sugar layer in glaucoma
This study looks at a thin “sugar coating” on the inside surface of the eye (the endothelial glycocalyx) in people with primary open-angle glaucoma and compares it with people without optic nerve disease. The results may help researchers better understand how glaucoma affects the eye.
ParisAges 18 years+
Hear when a new Ophthalmology trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for ophthalmology?
- Yes. Clin2 currently lists 45 recruiting ophthalmology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ophthalmology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ophthalmology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.