Clinical trials
Ophthalmology clinical trials
Below are recruiting ophthalmology clinical trials, each written for real people, not researchers. We’re tracking 45 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT05372861Recruiting
Eye test using nanopore sequencing for endophthalmitis
This trial studies endophthalmitis, an infection inside the eye, using a genetic test to better understand what’s causing it. It may help doctors learn more about the infection and guide treatment decisions in the future.
Graz, StyriaAges 18–99 - NCT05694858RecruitingPhase 1/Phase 2
Numbing patch comparison before blood draw for eye care
This trial tests a numbing skin patch made with tiny microneedles against a standard numbing cream/patch to reduce pain before a blood draw. It may help you feel less discomfort during venepuncture before an eye procedure.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT06074731Recruiting
Eye imaging study using a new scanner
This trial uses a special eye scanner to look at eye diseases. It might help doctors see eye problems more clearly.
Linz, Upper AustriaAges 5–110 - NCT06217588Recruiting
LCAT Deficiency Natural History Study
This study tracks people with LCAT deficiency over time to learn more about how the condition affects the body. It does not test a treatment, but helps researchers understand the disease better so they can design future studies.
Philadelphia, PennsylvaniaAges Any age - NCT06582472Recruiting
Early eye changes and diabetes trial
This study looks at early damage to the retina (the back of the eye) in people with type 2 diabetes, even before vision problems start. It aims to find new ways to detect and treat diabetic eye disease early.
Milan, Italy/milanAges 40–80 - NCT06643338Recruiting
Testing AI to spot eye nerve conditions in the ER
This trial is testing a new computer system that uses photographs of the back of your eye (color fundus photos) to help doctors quickly identify certain nerve or vision problems in the emergency room. If you come to the specific hospital and meet the basic requirements, this study will take pictures of your eyes to see if the AI can spot conditions more accurately.
ParisAges 18 years+ - NCT06692751Recruiting
Eye scan for microvascular angina
This study tests if a non-invasive eye scan (OCT-A) can detect changes in tiny blood vessels in the retina of people with chest pain caused by problems with the heart's small arteries (microvascular angina). If it works, it could be a simpler way to diagnose this condition.
DijonAges 18 years+ - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT06763731RecruitingPhase 4
Optimizing the eye surface with Systane COMPLETE before cataract surgery
This study tests whether using Systane COMPLETE eye drops before cataract surgery can improve the eye surface in people with dry eye. If you have dry eye and are scheduled for cataract surgery, this trial may help improve your eye comfort and surgery outcomes.
Taipei, TaiwanAges 20–85 - NCT06886373RecruitingPhase 4
Systane drops before and after cataract surgery for dry eye
This study tests whether using Systane COMPLETE eyedrops before and after cataract surgery helps improve dry eye symptoms and eye comfort. It is for people who were in a previous related trial or are new cataract patients with dry eye.
TaipeiAges 20–85 - NCT06948357RecruitingPhase 2
Eye drops for presbyopia in Chinese adults
This trial tests two eye drops, BRIMOCHOL PF and CARBACHOL PF, to see if they improve near vision in people with presbyopia (age-related difficulty seeing up close). The study is for Chinese adults aged 45-75 who have trouble reading even with glasses or contacts.
Wenzhou, ZhejiangAges 45–75 - NCT07178600Recruiting
Eye drops for surgery: side effects study
This study looks at how patients react to a common eye drop used before surgery. It helps understand side effects and who might be affected.
Mexico City, Mexico CiyAges 18 years+ - NCT00227253Recruiting
Study center for people with Chromosome 18
This trial is for people with Chromosome 18 (or the parent/guardian of a child with it) to take part in medical checkups and study evaluations. It may help researchers learn more about the condition and how to best evaluate patients safely.
San Antonio, TexasAges Any age - NCT02576925Recruiting
Predicting the cause of brief double vision episodes
This trial looks at a way to predict what causes short-lasting double vision. It may help doctors choose the right next steps faster after symptoms stop.
ParisAges 18 years+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT07428668Recruiting
Laser treatment for eye pressure changes in glaucoma
This trial tests a laser treatment called DSLT to see how it affects eye pressure changes over 6 months. It may help people with open-angle glaucoma or high eye pressure who are currently using 0 to 3 types of pressure-lowering eye drops.
Fort Worth, TexasAges 18 years+ - NCT07586787Recruiting
Early Vitrectomy vs Laser for Early Diabetic Eye Disease
This trial compares two treatments for early diabetic retinopathy—a condition where high blood sugar damages blood vessels in the eye. Researchers want to see if removing fluid from inside the eye (vitrectomy) works better than laser treatment to prevent vision loss.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07653074Recruiting
Vision and quality of life in youth with myopia or CVI
This study looks at how vision problems like nearsightedness (myopia) and a brain-based vision condition (CVI) affect daily life and well-being in children. It aims to understand what support they might need to thrive in a modern world.
ÖrebroAges Up to 17 years - NCT07096232Enrolling by invitation
AI vs doctor for eye surgery and keratoconus diagnosis
This study compares an AI system to a specialist eye doctor to see which is better at diagnosing vision problems like nearsightedness, farsightedness, astigmatism, and keratoconus. Your existing medical records will be used to see how well the AI performs.
Cairo, MaadiAges Any age - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+
Hear when a new Ophthalmology trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for ophthalmology?
- Yes. Clin2 currently lists 45 recruiting ophthalmology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ophthalmology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ophthalmology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.