Clinical trials
Ophthalmology clinical trials
Below are recruiting ophthalmology clinical trials, each written for real people, not researchers. We’re tracking 44 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06859216Recruiting
Testing AI-made plain language summaries for eye clinic notes
This study tests whether using artificial intelligence (AI) to create easy-to-read summaries of your eye doctor's notes helps people better understand their eye care. If you are an English-speaking patient at the Jules Stein Eye Institute, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT05694858RecruitingPhase 1/Phase 2
Numbing patch comparison before blood draw for eye care
This trial tests a numbing skin patch made with tiny microneedles against a standard numbing cream/patch to reduce pain before a blood draw. It may help you feel less discomfort during venepuncture before an eye procedure.
Kuala Lumpur, Kuala LumpurAges 18 years+ - NCT06766357RecruitingPhase 3
Cyclosporin gel for moderate to severe dry eye
This study tests a gel form of cyclosporine for people with moderate to severe dry eye that hasn't improved with other treatments. The gel is applied to the eye to help reduce inflammation and increase tear production.
Xiamen, FujianAges 18 years+ - NCT06763731RecruitingPhase 4
Optimizing the eye surface with Systane COMPLETE before cataract surgery
This study tests whether using Systane COMPLETE eye drops before cataract surgery can improve the eye surface in people with dry eye. If you have dry eye and are scheduled for cataract surgery, this trial may help improve your eye comfort and surgery outcomes.
Taipei, TaiwanAges 20–85 - NCT05294978Recruiting
Testing a new light-based treatment for certain eye vision loss
This trial studies a light-guided eye treatment in people with generalized inherited retinal disease (a genetic cause of vision loss). It aims to see whether the approach works safely and can improve function for people whose vision is already significantly reduced.
San Francisco, CaliforniaAges Any age - NCT06692751Recruiting
Eye scan for microvascular angina
This study tests if a non-invasive eye scan (OCT-A) can detect changes in tiny blood vessels in the retina of people with chest pain caused by problems with the heart's small arteries (microvascular angina). If it works, it could be a simpler way to diagnose this condition.
DijonAges 18 years+ - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT04389437Recruiting
Eye imaging study for people with memory problems
This study uses detailed eye scans to look for changes that might relate to memory problems. You may be able to join if you are being seen for memory concerns and meet the health and eye-scan requirements.
ParisAges 18 years+ - NCT05372861Recruiting
Eye test using nanopore sequencing for endophthalmitis
This trial studies endophthalmitis, an infection inside the eye, using a genetic test to better understand what’s causing it. It may help doctors learn more about the infection and guide treatment decisions in the future.
Graz, StyriaAges 18–99 - NCT06217588Recruiting
LCAT Deficiency Natural History Study
This study tracks people with LCAT deficiency over time to learn more about how the condition affects the body. It does not test a treatment, but helps researchers understand the disease better so they can design future studies.
Philadelphia, PennsylvaniaAges Any age - NCT05847894Recruiting
AI eye scans to help diagnose lung breathing problems
This trial tests an artificial intelligence (AI) tool that uses eye images to help doctors diagnose breathing or lung-related conditions. If you have a lung/breathing problem and can do both eye and lung checkups, it may support faster or more accurate diagnosis.
Guangzhou, GuangdongAges Any age - NCT04681417RecruitingPhase 2/Phase 3
Eye-sparing treatment options for children with retinoblastoma
This trial studies whether newer “save-the-eye” treatment plans can control retinoblastoma (eye cancer) while keeping vision as good as possible. It compares different conservative treatment strategies depending on how the tumor looks and where it is.
Saint-Denis, La RéunionAges 6 months–6 years - NCT05264818Recruiting
Study measures eye surface sugar layer in glaucoma
This study looks at a thin “sugar coating” on the inside surface of the eye (the endothelial glycocalyx) in people with primary open-angle glaucoma and compares it with people without optic nerve disease. The results may help researchers better understand how glaucoma affects the eye.
ParisAges 18 years+ - NCT04451265Recruiting
MRI test study for suspected anterior optic nerve stroke
This study checks how well a special MRI scan (diffusion-weighted imaging) can identify a specific optic nerve problem called anterior ischemic optic neuropathy (when blood flow to the optic nerve is reduced). If you have symptoms that suggest this condition, the trial compares your MRI findings to doctors’ assessment to see if the scan helps confirm the diagnosis.
Lille, LilleAges 18 years+ - NCT04959838Recruiting
Study of job stress in eye doctors and trainees
This study looks at job stress among ophthalmologists (eye doctors) and ophthalmology residents. It may help improve working conditions and support for people in eye care.
Clermont-FerrandAges 18–65 - NCT00227253Recruiting
Study center for people with Chromosome 18
This trial is for people with Chromosome 18 (or the parent/guardian of a child with it) to take part in medical checkups and study evaluations. It may help researchers learn more about the condition and how to best evaluate patients safely.
San Antonio, TexasAges Any age - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03381794Recruiting
Cornea transplant registry for patients in Germany
This trial is not testing a new treatment. It collects and organizes information about people in Germany who have had a corneal (front-of-eye) transplant since 2001 to help future care and research.
Homburg, SaarlandAges 1–100 - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT02576925Recruiting
Predicting the cause of brief double vision episodes
This trial looks at a way to predict what causes short-lasting double vision. It may help doctors choose the right next steps faster after symptoms stop.
ParisAges 18 years+
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Common questions
- Are there clinical trials for ophthalmology?
- Yes. Clin2 currently lists 44 recruiting ophthalmology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ophthalmology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ophthalmology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.