Eye disorders in dominant spinal-cerebellar ataxias
Part of Brain & nervous system, Genetic & congenital clinical trials.
This trial looks for eye problems in people with certain genetic forms of spinocerebellar ataxia (SCA1, SCA2, SCA3, or SCA27B). You have to be between 18 and 80 years old and have a specific genetic mutation. You can join if you already have symptoms or if you are at risk but do not have symptoms yet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have a specific genetic change (expansion) in the ATXN1, ATXN2, ATXN3, or FGF14 gene that causes spinocerebellar ataxia.
- You either have symptoms of ataxia (like trouble walking or coordinating) or you are a carrier without symptoms.
- You do not have other eye diseases or conditions that would prevent a clear eye exam, like severe cataracts, uncontrolled diabetes, or very poor vision.
- You are able to sit for eye exams and do not have very severe neurological problems that would make the exams impossible.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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