Clinical trials
Optic Neuritis clinical trials
Below are recruiting optic neuritis clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05540262Recruiting
Edaravone for new anti-AQP4 optic neuritis
This trial tests edaravone, a medicine intended to reduce damage from optic neuritis, in adults whose condition is confirmed by a positive blood test for anti-AQP4 antibodies. It may help people who are in the first month after their first episode to preserve or improve vision.
NanningAges 18–70 - NCT06453694RecruitingPhase 2
Efgartigimod for first-time optic neuritis
This trial tests a drug called efgartigimod for people having their first episode of optic neuritis (inflammation of the optic nerve). The goal is to see if it can help protect your vision better than standard treatment alone.
Boston, MassachusettsAges 18 years+ - NCT07623252Recruiting
Testing new diagnostic criteria for optic nerve inflammation
This study evaluates new guidelines for diagnosing optic neuritis, a condition where the nerve that carries vision becomes inflamed. If you have sudden vision loss in one or both eyes and your doctor thinks optic neuritis might be the cause, this trial will help confirm the diagnosis using updated diagnostic criteria.
Nanning, GuangxiAges Any age - NCT02521311RecruitingPhase 2
Clemastine to help restore nerve covering in optic neuritis
This Phase 2 trial tests whether clemastine can help regrow the protective covering around the optic nerve after acute optic neuritis (an inflammation-related vision problem). It may help improve vision recovery and signal how well “remyelination” happens.
San Francisco, CaliforniaAges 18–55 - NCT07100990RecruitingPhase 3
Early plasma exchange for optic neuritis or myelitis
This trial tests if getting plasma exchange early, along with high-dose steroids, helps people with severe optic neuritis or transverse myelitis recover better than waiting to see if steroids alone work. It aims to find out if faster treatment can prevent lasting vision loss or disability.
Scottsdale, ArizonaAges 18 years+ - NCT06389968Recruiting
Light therapy for vision after optic neuritis in MS
This study tests whether light stimulation can help improve vision after optic neuritis in people with multiple sclerosis. It may offer a way to support eye recovery without medication.
Munich, BavariaAges 18–60 - NCT07623668RecruitingPhase 3
Testing a new drug for sudden vision loss from nerve inflammation
This study tests whether a new medication called privosegtor can help restore vision in people who recently experienced sudden vision loss in one eye due to optic nerve inflammation. You would receive the study drug early after your symptoms start, when treatment may be most effective.
Livonia, MichiganAges 18–50 - NCT04448938Recruiting
MRI study for optic neuritis recovery signals
This study uses a special MRI scan while you rest to look for brain and eye signals that may relate to recovery in people with suspected optic neuritis. If you’re eligible, it may help researchers better understand what predicts vision improvement.
Paris, PARISAges 18 years+ - NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT05017142Recruiting
Pediatric brain inflammation registry for Swiss patients
This study is a registry that collects health information from children and teens in Switzerland diagnosed with certain inflammatory brain and spinal cord conditions. It helps researchers understand these illnesses better over time and may guide future treatments.
Aarau, Canton of AargauAges Up to 36 years - NCT05487989Recruiting
Visual pathway study for recent optic neuritis
This study looks at how the eye-to-brain visual pathways work in people who have had optic neuritis symptoms for less than 4 weeks. It may help researchers better understand neuro-inflammatory (nerve inflammation) disorders and improve future care.
LilleAges 18–65 - NCT06494228Recruiting
Comparing MRI scans for optic neuritis
This study compares three types of brain MRI scans (3D FLAIR, DIR, and PSIR) to see which is best at detecting optic neuritis (inflammation of the optic nerve). It looks at scans from patients with multiple sclerosis or NMO spectrum disorder to improve diagnosis.
Strasbourg, Les Hôpitaux Universitaires de StrasbourgAges 18 years+
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Common questions
- Are there clinical trials for optic neuritis?
- Yes. Clin2 currently lists 12 recruiting optic neuritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a optic neuritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a optic neuritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.