Clinical trials
Optic Nerve Diseases clinical trials
Below are recruiting optic nerve diseases clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06139523Recruiting
Improving eye imaging in adults and children
This study aims to improve how we take pictures of the back of the eye (called OCT imaging) in both healthy adults and children. It will help doctors get better images to diagnose and manage eye conditions.
Durham, North CarolinaAges Any age - NCT06841575Recruiting
Better eye imaging for children and adults at Duke
This study tests a new camera that automatically adjusts to take clear pictures of the back of the eye. It aims to improve retinal imaging for healthy adults, adult eye clinic patients, and children seen at Duke Eye Center.
Durham, North CarolinaAges 1 month+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT04607369Enrolling by invitation
Test using an app to map eye vision blind spots
This trial tests how well an EyeCTester smartphone app can measure vision blind spots and distorted vision compared with standard eye tests. If you qualify, you’ll do short near-vision and “Amsler grid” style tasks in the clinic to help confirm the app is accurate.
Bellaire, TexasAges 18 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05749094Recruiting
Ultrasound of the optic nerve in new suspected giant eye artery disease
This trial studies whether a quick ultrasound of the optic nerve (plus an eye exam) can help evaluate new suspected giant cell arteritis (GCA). It may help doctors assess eye risk early and decide on the best next steps.
London, OntarioAges 50–99 - NCT04634383Recruiting
Testing a brain-connected implant to help some blind people see
This early safety study tests an implanted device placed in the brain to help people with very limited sight (no or minimal light). It focuses on whether the implant can be safely used and whether it may support vision-related signals over time.
Chicago, IllinoisAges 19–70 - NCT07491198Recruiting
Head-Down Position and Eye Pressure in Prostate Surgery
This study looks at how the steep head-down position (Trendelenburg) and gas inflation during robot-assisted prostate surgery affect the sheath around the optic nerve. It aims to understand eye pressure changes to improve safety.
IzmirAges 18 years+ - NCT07539831Recruiting
Menstrual cycle effects during minimally invasive gynecology surgery
This study examines how the menstrual cycle may affect pressure in the optic nerve (the nerve connected to your eye) during laparoscopic gynecologic surgery. Researchers want to understand if the timing of surgery within your cycle matters for eye and brain safety.
KonyaAges 18–45 - NCT06979700Recruiting
Early wake-up predictors after cardiac arrest
This study looks at patients who had a cardiac arrest outside the hospital and are still unconscious after their heartbeat returns. The goal is to find early signs that predict when someone will wake up.
Aarhus NAges 18 years+ - NCT06748703Recruiting
Optic nerve injury in obstructive sleep apnea patients
This study looks at whether sleep apnea affects the optic nerve, which connects your eye to your brain. It is for people newly diagnosed with sleep apnea who have not yet received treatment.
Nanjing, JiangsuAges 18–80 - NCT07290244RecruitingPhase 1
Testing ER-100 safety for glaucoma or NAION patients
This trial tests whether a new drug, ER-100, is safe for people with glaucoma or a sudden optic nerve injury called NAION. It aims to see if the drug can be given without serious side effects.
Glendale, CaliforniaAges 40–85 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07666984RecruitingPhase 4
Effect of two reversal drugs on optic nerve sheath size
This trial compares two medications given after surgery to see how they affect the size of the sheath around your optic nerve, which can show changes in brain pressure. It helps doctors understand which medication might be safer for your eyes and brain.
AdanaAges 18–65 - NCT07001059Recruiting
Ultrasound to see nerve swelling in giant cell arteritis
This trial uses an ultrasound to check for swelling around the optic nerve in people who may have giant cell arteritis (GCA). It aims to see if this test can help diagnose GCA faster.
Aix-en-ProvenceAges 50 years+ - NCT07303296RecruitingPhase 2
Gene therapy study for vision loss from LHON
This trial tests a gene therapy called GS010 given as an injection into the eye for people with vision loss from LHON. It aims to see if it can help improve vision in both eyes.
ParisAges 15 years+ - NCT02841553Recruiting
Online registry for Wolfram syndrome worldwide
This study builds an international online registry to learn how Wolfram syndrome (and related WFS1 conditions) changes over time. It may help researchers understand the disease course and improve future care by collecting health and family history data.
St Louis, MissouriAges birth+ - NCT07452367Recruiting
Bentall surgery study: optic nerve and thinking ability
This study checks if swelling of the optic nerve sheath during heart surgery with a bypass machine is linked to changes in thinking ability after the operation. It may help understand why some people have mental fogginess after surgery.
Bursa, YıldırımAges 18–80 - NCT07464938Recruiting
Predicting brain recovery after cardiac arrest
This study is testing new tools and markers to better predict recovery after cardiac arrest when brain injury may occur. It involves adults who had a cardiac arrest outside the hospital and are being treated at Saint-Luc hospital.
BrusselsAges 18 years+ - NCT07396441RecruitingPhase 4
Kelulut honey therapy for juvenile glaucoma
This trial tests if adding Kelulut honey to standard treatment can help protect the optic nerve in young people with juvenile open-angle glaucoma. It looks at eye pressure, nerve thickness, and dry eye symptoms.
Kota Bharu, KelantanAges 15–40 - NCT07085533Recruiting
A Study of Inherited Retinal Diseases
This study is looking at how inherited retinal diseases affect color vision over time. It may help researchers understand these conditions better and is a good fit for people with a known diagnosis who can describe what they see.
WuhanAges Any age
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Common questions
- Are there clinical trials for optic nerve diseases?
- Yes. Clin2 currently lists 23 recruiting optic nerve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a optic nerve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a optic nerve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.