Clemastine to help restore nerve covering in optic neuritis
Part of Brain & nervous system, Eyes & vision, Immune system & allergy, Pain clinical trials.
This Phase 2 trial tests whether clemastine can help regrow the protective covering around the optic nerve after acute optic neuritis (an inflammation-related vision problem). It may help improve vision recovery and signal how well “remyelination” happens.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had sudden vision symptoms from optic neuritis in one eye within the last 3 weeks (not just pain).
- Your doctor thinks it is demyelinating optic neuritis (or you’re being evaluated as such).
- If you can become pregnant, you can use reliable birth control during the study and understand pregnancy rules.
- You can sign informed consent and understand what the study involves.
- You do NOT have other major eye problems (like glaucoma, macular degeneration, severe diabetes-related eye disease) that would explain your symptoms.
- Key safety checks are okay (for example, no severe eye hemorrhage, no complete vision loss in the affected eye, and blood/liver/kidney tests are within limits).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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