Clinical trials
Oral Leukoplakia clinical trials
Below are recruiting oral leukoplakia clinical trials, each written for real people, not researchers. We’re tracking 8 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03975322Recruiting
Predict which oral white patches may turn cancerous
This study looks at oral leukoplakia (persistent white patches in the mouth) to better predict which ones may develop into cancer. It uses a test based on specific immune and cancer-related markers to help estimate each person’s risk.
ErlangenAges 18–80 - NCT06321003Recruiting
Testing AI to detect early oral cancer with light scans
This trial uses a special light-based scanner (OCT) and artificial intelligence to help diagnose early signs of mouth cancer or precancer. It aims to see if this combination can make diagnosis easier and more accurate.
PalermoAges 18–99 - NCT07682883Enrolling by invitation
Mouth screening to prevent oral cancer
This study checks how well routine mouth exams can find early signs of oral cancer. It is for adults who do not already have a condition called OPMD (a mouth problem that can lead to cancer) and are not being treated for it.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07210775RecruitingPhase 1/Phase 2
Imiquimod cream for mouth precancer
This trial tests a cream called imiquimod for people who have been diagnosed with oral dysplasia, a precancerous condition in the mouth. It is an option for those who cannot or choose not to have surgery or laser treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07387900RecruitingPhase 2
Metformin for preventing cancer in oral leukoplakia
This study tests if metformin — a medication commonly used for diabetes — can prevent oral leukoplakia from turning into cancer when applied as a mouth rinse and taken as a pill. It is for people with non-severe white patches in the mouth.
CairoAges 21 years+ - NCT07331935Recruiting
Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia
This study tests whether a cream containing coenzyme Q10 and curcumin can help treat a common mouth condition called oral leukoplakia (a white patch that can sometimes turn into cancer). It is for people with a specific type of white patch that is not severe and can be easily reached with a cream.
AlexandriaAges 40 years+ - NCT03603223RecruitingPhase 2
Pembrolizumab for abnormal mouth patches that may become cancer
This Phase 2 trial studies pembrolizumab (an immune medicine) for leukoplakia and related abnormal mouth patches with moderate/severe pre-cancer changes. It aims to see whether the treatment can shrink or control the lesions when surgery or radiation isn’t an option.
La Jolla, CaliforniaAges 18 years+ - NCT05727761RecruitingPhase 2
Pioglitazone plus metformin for high-risk mouth lesions
This trial studies whether a two-medicine diabetes drug combination can reduce or control risky early changes in certain mouth and throat lesions. You may be asked for small tissue samples (biopsies) before and after 12 weeks to see how the lesions respond.
Minneapolis, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for oral leukoplakia?
- Yes. Clin2 currently lists 8 recruiting oral leukoplakia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral leukoplakia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral leukoplakia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.