Metformin for preventing cancer in oral leukoplakia
Treatments studied
Part of Cancer, Mouth & dental clinical trials.
This study tests if metformin — a medication commonly used for diabetes — can prevent oral leukoplakia from turning into cancer when applied as a mouth rinse and taken as a pill. It is for people with non-severe white patches in the mouth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years or older.
- You have a biopsy-confirmed mouth white patch (oral leukoplakia) with mild to moderate cell changes.
- You are not currently taking metformin or certain stomach acid medications (like ranitidine).
- You do not have serious heart, lung, kidney, or liver disease.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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