Clinical trials
Pain After Surgery clinical trials
Below are recruiting pain after surgery clinical trials, each written for real people, not researchers. We’re tracking 417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07846722Recruiting
Comparing two medicines to reduce pain medicine use after laparoscopic hysterectomy
This study compares two drugs, esmolol and dexmedetomidine, to see which one better reduces the need for strong painkillers after laparoscopic hysterectomy. It may help you manage pain with fewer opioids.
AthensAges 20–70 - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT06091241Recruiting
Nerve blocks for pain relief after DIEP breast reconstruction
This trial compares two types of nerve blocks (ESPBs and TAPs) to see which provides better pain control after DIEP flap surgery for breast cancer. Women with breast cancer who are otherwise healthy or have mild to moderate medical conditions may be able to join.
Kansas City, KansasAges 18–70 - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT07184463Recruiting
Pain reduction after lung surgery using different robot methods
This trial compares three ways to do robotic lung surgery to see which one causes less pain afterward. If you are having lung surgery, it may help your recovery be more comfortable.
Montreal, QuebecAges 18 years+ - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07311369RecruitingPhase 2
Testing a new pain tablet after abdominal surgery
This trial tests a new pain tablet (HL-1186) for people having abdominal surgery. It aims to see if the tablet is safe and works well to manage pain after the operation.
Changsha, HunanAges 18–75 - NCT06931743Recruiting
Electrical stimulation for pain after thyroid surgery
This trial tests if electrical stimulation can help reduce pain after thyroid surgery. It is for people who have at least moderate pain after their operation.
Shanghai, Changning DistrictAges 18 years+ - NCT06404983Recruiting
Opioid-free anesthesia for breast cancer surgery
This study tests whether breast cancer surgery can be done safely without using opioid pain medicines during anesthesia. The goal is to see if avoiding opioids leads to fewer side effects and a smoother recovery.
Ioannina, EpirusAges 18–99 - NCT07555496Recruiting
Back Pain Treatment After Spine Surgery: Injection vs. Needling
This study compares two ways to treat long-lasting back pain in people who have had spine surgery: injections into the back muscles versus dry needling (inserting thin needles into tight muscles). Both are combined with physical therapy to see which helps reduce pain better.
St-MaloAges 18 years+ - NCT07081373Recruiting
Repeat dose of liposomal bupivacaine for pain after anal fistula surgery
This trial tests if a repeat dose of liposomal bupivacaine (a long-acting numbing medicine) helps reduce pain after surgery for anal fistula. It may be a good option if you are having this surgery and want better pain control.
Guangzhou, GuangdongAges 18–60 - NCT07467356RecruitingPhase 3
Nerve blocks for easier positioning before hip surgery
This study compares two different numbing injections (nerve blocks) to see which one helps you get into position more easily for spinal anesthesia before hip surgery. The goal is to make the procedure less painful and more comfortable.
Banhā, ElqalyoubeaAges 18 years+ - NCT07716540Recruiting
Pain relief injection for hip fracture surgery
This study tests whether a special numbing injection (deep iliacus plane block) can better control pain after hip fracture surgery. If you're having hip surgery under spinal anesthesia, researchers want to see if this extra block helps you recover with less pain.
Istanbul, IstanbulAges 18 years+ - NCT07712432Recruiting
Insomnia and pain after dental surgery study
This study looks at how sleep problems might affect pain after dental surgery. If you are having a tooth removed, you may be able to help by filling out some questionnaires.
RomaAges 18 years+ - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT06488183Recruiting
Pain relief study for laparoscopic weight loss surgery
This study compares two ways to manage pain after laparoscopic bariatric surgery: one method involves numbing medicine placed near the surgery site, and the other uses an ultrasound-guided injection near the back. It aims to find which option works better for recovery in people with moderate to severe obesity.
AlexandriaAges 20–50 - NCT07412223RecruitingPhase 4
Tegileridine for bowel recovery after abdominal surgery
This trial tests a painkiller called Tegileridine to see if it helps your bowels work normally again after abdominal surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07354581Recruiting
Pain blocks after lower back surgery
This trial compares two types of pain-block injections (erector spinae plane block versus quadro-iliac plane block) given during lower back surgery to see which controls pain better. It may help you have less pain and need fewer pain medicines after your operation.
BursaAges 18–65 - NCT06664203Recruiting
Nerve block for arm surgery pain relief
This trial tests a special type of nerve block (called variable volume truncal block) for pain relief during arm, elbow, forearm, hand, or wrist surgery. It may help reduce pain and the need for strong pain medicines.
IstanbulAges 18–65 - NCT05824832RecruitingPhase 4
Buprenorphine, clonidine, and steroid to extend arm nerve block
This study tests whether adding certain medicines (buprenorphine, clonidine, and a steroid) to an arm “nerve block” during shoulder surgery can help the numbness last longer and improve comfort afterward. It is for adults having shoulder arthroscopy and compares how long the nerve block works.
Maywood, IllinoisAges 18 years+ - NCT07311902Recruiting
Comparing two blocks for pain after hernia repair
This trial compares two types of nerve blocks (M-Tapa block and TAP block) to see which one works better for controlling pain after open inguinal hernia repair. It may help find a better way to manage pain after surgery.
ErzurumAges 18–65
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Common questions
- Are there clinical trials for pain after surgery?
- Yes. Clin2 currently lists 417 recruiting pain after surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain after surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain after surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.