Clinical trials
Pain After Surgery clinical trials
Below are recruiting pain after surgery clinical trials, each written for real people, not researchers. We’re tracking 419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07295184Recruiting
Rebound pain and confusion after hip surgery
This study looks at a way to reduce confusion after hip surgery. If you are having planned hip surgery and get a nerve block for pain, researchers will check if rebound pain affects your recovery in the hospital.
Konya, KaratayAges 18–80 - NCT07021105Enrolling by invitation
Comparing nerve blocks for pain after gynecological surgery
This study tests two different types of nerve blocks (called 'plain blocks') to see which one works better for controlling pain after major gynecological surgery. You would receive one of the blocks before surgery, and then use a pump you control to get extra pain medicine as needed.
Adana, SarıçamAges 18–69 - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT06091241Recruiting
Nerve blocks for pain relief after DIEP breast reconstruction
This trial compares two types of nerve blocks (ESPBs and TAPs) to see which provides better pain control after DIEP flap surgery for breast cancer. Women with breast cancer who are otherwise healthy or have mild to moderate medical conditions may be able to join.
Kansas City, KansasAges 18–70 - NCT05862792Recruiting
Liposomal bupivacaine during robotic throat surgery
This study gives a pain-relief medicine (bupivacaine in a slow-release form) during transoral robotic throat surgery. It aims to see if it improves comfort and pain control around the time of surgery.
Danville, PennsylvaniaAges 18 years+ - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT07184463Recruiting
Pain reduction after lung surgery using different robot methods
This trial compares three ways to do robotic lung surgery to see which one causes less pain afterward. If you are having lung surgery, it may help your recovery be more comfortable.
Montreal, QuebecAges 18 years+ - NCT04874038RecruitingPhase 3
Lidocaine infusions to prevent long-lasting pain after breast surgery
This Phase 3 study tests whether receiving lidocaine through an IV during breast surgery can lower the chance of ongoing pain afterward. If it works, it may help some people avoid chronic, surgery-related pain in the chest wall, shoulder, or arm.
Calgary, AlbertaAges 18–100 - NCT07311369RecruitingPhase 2
Testing a new pain tablet after abdominal surgery
This trial tests a new pain tablet (HL-1186) for people having abdominal surgery. It aims to see if the tablet is safe and works well to manage pain after the operation.
Changsha, HunanAges 18–75 - NCT06404983Recruiting
Opioid-free anesthesia for breast cancer surgery
This study tests whether breast cancer surgery can be done safely without using opioid pain medicines during anesthesia. The goal is to see if avoiding opioids leads to fewer side effects and a smoother recovery.
Ioannina, EpirusAges 18–99 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07603323Recruiting
Pain Relief Methods for Meniscus Knee Surgery
This study compares two different numbing techniques (ACB and ACB combined with BiFeS) to see which one better controls pain after meniscus surgery. The meniscus is cartilage in your knee that can tear and cause pain.
AnkaraAges 18–65 - NCT06931743Enrolling by invitation
Electrical stimulation for pain after thyroid surgery
This trial tests if electrical stimulation can help reduce pain after thyroid surgery. It is for people who have at least moderate pain after their operation.
Shanghai, Yangpu DistrictAges 18 years+ - NCT06886932Recruiting
Pain education after rotator cuff surgery
This trial tests if learning about pain before and after rotator cuff repair helps people recover better. It might help you if you have a medium-sized tear and are planning surgery.
KaramanAges 40–75 - NCT06387303RecruitingEarly Phase 1
Comparing IV Methadone vs Spinal Morphine for Pain After Abdominal Surgery
This study compares two strong painkillers—methadone given through an IV versus morphine injected into the spine—to see which provides better pain relief and recovery after major abdominal surgery. It may help you if you're having open surgery and want less pain afterward.
Charlottesville, VirginiaAges 18–75 - NCT07081373Recruiting
Repeat dose of liposomal bupivacaine for pain after anal fistula surgery
This trial tests if a repeat dose of liposomal bupivacaine (a long-acting numbing medicine) helps reduce pain after surgery for anal fistula. It may be a good option if you are having this surgery and want better pain control.
Guangzhou, GuangdongAges 18–60 - NCT07716540Recruiting
Pain relief injection for hip fracture surgery
This study tests whether a special numbing injection (deep iliacus plane block) can better control pain after hip fracture surgery. If you're having hip surgery under spinal anesthesia, researchers want to see if this extra block helps you recover with less pain.
Istanbul, IstanbulAges 18 years+ - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120 - NCT04577690RecruitingPhase 4
PECS pain study for children getting a chest device implanted
This trial tests a pain-control method (PECS) during surgery for children who are having a small chest device implanted. It may help reduce discomfort during and after the operation.
Toronto, OntarioAges 3–18 - NCT05351229RecruitingPhase 4
Spinal morphine for pain control after lung surgery
This trial tests whether putting morphine into the spinal area during lung surgery can reduce pain after surgery for people having certain minimally invasive lung operations. It aims to improve comfort and possibly reduce the need for other pain medicines.
Chicago, IllinoisAges 18–80 - NCT05824832RecruitingPhase 4
Buprenorphine, clonidine, and steroid to extend arm nerve block
This study tests whether adding certain medicines (buprenorphine, clonidine, and a steroid) to an arm “nerve block” during shoulder surgery can help the numbness last longer and improve comfort afterward. It is for adults having shoulder arthroscopy and compares how long the nerve block works.
Maywood, IllinoisAges 18 years+ - NCT06100172Recruiting
Ear Stimulation After Back Surgery
This study tests whether a gentle electrical stimulation placed on the ear (tAuricular Neurostimulation) can help reduce pain and improve recovery after lumbar spine surgery. It is for people who are already scheduled for a lumbar fusion or laminectomy and want to see if this non-invasive approach can ease their post-surgery discomfort.
Dallas, TexasAges 18–85
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Common questions
- Are there clinical trials for pain after surgery?
- Yes. Clin2 currently lists 419 recruiting pain after surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain after surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain after surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.