Clinical trials · Philadelphia, PA
Pain clinical trials in Philadelphia
We’re tracking 42 recruiting pain studies with a site in or near Philadelphia — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT07044323Recruiting
Virtual reality for phantom limb pain after leg amputation
This study tests whether using virtual reality at home for 30 minutes a day can reduce phantom limb pain after a leg amputation. It aims to improve how your brain handles pain signals.
Philadelphia, PennsylvaniaAges 18–100 - NCT06139666Enrolling by invitationPhase 4
Liposomal bupivacaine nerve block for rotator cuff surgery
This study tests whether a long-lasting numbing medicine called liposomal bupivacaine (Exparel) works better than standard pain relief for people having rotator cuff surgery. It aims to lessen pain after surgery so you may need fewer pain pills.
Camden, New JerseyAges 18 years+ - NCT06133933Enrolling by invitation
Shoulder replacement and pain medication study
This study looks at how your pain tolerance before a total shoulder replacement might relate to how much pain medication you need after surgery. The goal is to help doctors better manage pain medication after surgery.
Camden, New JerseyAges 18 years+ - NCT05437575RecruitingPhase 3
Testing pain medicine given before arrival to a trauma center
This study tests whether giving pain medicine soon after an injury (before you reach the trauma center) improves comfort and care. You might be eligible if you’re transported to a participating trauma center and meet specific shock and pain levels.
Camden, New JerseyAges 18 years+ - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Media, PennsylvaniaAges 18–80 - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sewell, New JerseyAges 22–80 - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Trevose, PennsylvaniaAges 18 years+ - NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
Trevose, PennsylvaniaAges 18 years+ - NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Chadds Ford, PennsylvaniaAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Exton, PennsylvaniaAges 18 years+ - NCT05764681Recruiting
Study for long-term pain after surgery
This study is for people who have chronic post-surgical pain and have a planned surgery on a leg or the spine. The goal is to better understand this long-term pain and what may help manage it after surgery.
Wilmington, DelawareAges 5–17 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Wilmington, DelawareAges birth–20 years - NCT03427736Recruiting
Studying pain and numbing medicines in children
This trial looks at how well different numbing and pain-relief medicines work in children during routine care. It may help doctors choose safer, better pain control for kids who need these medicines.
Wilmington, DelawareAges birth–17 years - NCT07054840Recruiting
Pain and walking learning in older adults
This study looks at how pain affects learning to walk on a special treadmill that moves each leg at a different speed. It's for healthy older adults who want to understand how pain might change the way they learn new walking patterns.
Newark, DelawareAges 55–90 - NCT05245695Recruiting
Endometriosis test using deep computer learning during surgery
This trial studies whether a computer (deep neural network) can better identify endometriosis in people with long-lasting pelvic pain using information from surgery. It may help doctors sort who has endometriosis more accurately when surgery is already planned.
Newark, DelawareAges 14–50 - NCT05612750Recruiting
Online therapy for chronic pain: CBT vs one-session relief
This study compares two online treatments for chronic pain: an 8-session cognitive behavioral therapy (CBT) program versus a single “empowered relief” session. It aims to see which approach helps people manage pain better over time.
Allentown, PennsylvaniaAges 18 years+ - NCT05986292RecruitingPhase 2
Study of new treatments for chronic pain
This study tests new treatments for chronic pain that lasts at least 3 months. Participants must stop their regular pain medicines and use only a rescue painkiller if needed. The goal is to find better ways to manage long-term pain.
Wyomissing, PennsylvaniaAges 18 years+
Hear when a new Pain trial opens near Philadelphia, PA
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Pain trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting pain studies listed above.
- Alfred I. duPont Hospital for Children · 3 studies
- Cooper University Health Care · 3 studies
- Fox Chase Pain Management · 2 studies
- Center for Interventional Pain & Spine
- Center for Interventional Pain and Spine
- Clinical Research Center of Reading, LLC
- Hassman Research Institute
- Health Sciences Complex
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in Pennsylvania.
Common questions
- Are there pain clinical trials near Philadelphia?
- Yes. We're currently tracking 42 recruiting pain studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.