Clinical trials · Los Angeles, CA
Pain clinical trials in Los Angeles
We’re tracking 87 recruiting pain studies with a site in or near Los Angeles — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Los Angeles
- NCT07308834RecruitingPhase 1/Phase 2
Knee injection study for moderate to severe osteoarthritis pain
This study tests a new knee injection called CX-011 to see if it can reduce pain and improve function in people with knee osteoarthritis. It may be a good option if you have tried other treatments without enough relief.
Los Angeles, CaliforniaAges 40–75 - NCT07122843Recruiting
VR and AI meditation for hospital pain relief
This study tests if a virtual reality (VR) meditation program can help reduce pain in hospitalized patients. If you have at least moderate pain (4 out of 10 or higher) and can speak English or Spanish, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
Los Angeles, CaliforniaAges 18 years+ - NCT06123286RecruitingEarly Phase 1
Tart cherry and omega-3s for joint pain from hormone therapy
This study tests whether taking tart cherry and omega-3 supplements can help reduce joint pain and stiffness caused by aromatase inhibitors (a common breast cancer treatment). If you have bothersome joint pain while on this hormone therapy, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT06859723RecruitingPhase 1
Effects of high potency cannabis on daily users
This study tests how high potency cannabis affects mood, thinking, and pain sensitivity in people who smoke cannabis almost every day. It will help researchers understand both immediate and long-lasting effects.
Los Angeles, CaliforniaAges 21–55 - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT05865470RecruitingPhase 1
How age affects smoked and oral THC effects
This early-stage study compares how people in different age groups respond to THC taken by smoking versus by mouth. It aims to understand age-related differences in effects and safety, which could help guide safer use in the future.
Los Angeles, CaliforniaAges 18–65 - NCT06661850Recruiting
Using Nociscan to guide discogenic low back pain surgery
This trial tests whether using a tool called Nociscan helps improve outcomes in people having surgery for low back pain caused by damaged discs. It may help doctors decide which discs need treatment.
Los Angeles, CaliforniaAges 18–70 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Los Angeles, CaliforniaAges 18–80 - NCT07605546Recruiting
Radiation Therapy for Cancer Pain Relief
This trial tests whether a focused radiation treatment called SRS (stereotactic radiosurgery) can help relieve severe cancer pain that hasn't improved with strong pain medications. You would receive a one-time radiation procedure aimed at pain-causing areas in your brain.
Los Angeles, CaliforniaAges 18 years+ - NCT05737121RecruitingPhase 2
Study drug for bladder pain compared with lidocaine, heparin, or placebo
This Phase 2 trial tests VNX001 to see if it helps people with interstitial cystitis/bladder pain syndrome (IC/BPS) compared with its separate ingredients (lidocaine and heparin) or a placebo (inactive treatment). You may be eligible if you have had IC/BPS for months and recently had a moderate-to-severe bladder pain flare.
Los Angeles, CaliforniaAges 18 years+ - NCT07310004Recruiting
VR vs Music for Breast Biopsy Anxiety
This trial compares using a virtual reality headset versus listening to relaxing music to help lower your anxiety and pain during a breast biopsy. Both methods are non-drug ways to help you feel more comfortable during the procedure.
Los Angeles, CaliforniaAges 18 years+ - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT04658628Recruiting
Brain scan study to learn who responds to spinal cord stimulation
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Los Angeles, CaliforniaAges 21 years+ - NCT06859710RecruitingPhase 1
THC and CBD as a harm reduction strategy
This study looks at whether different types of cannabis (containing THC and/or CBD) might help people who use cannabis regularly reduce potential harms. You will be asked to take cannabis in a controlled setting and complete tasks and questionnaires.
Los Angeles, CaliforniaAges 21–55 - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT06848348RecruitingPhase 2
Halneuron for chemotherapy-induced nerve pain
This trial tests whether the drug Halneuron can safely reduce nerve pain caused by common chemotherapy drugs (platinum and taxane). It is for people whose nerve pain started after chemotherapy and whose cancer is not currently getting worse.
Los Angeles, CaliforniaAges 18 years+ - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT06717308Recruiting
Testing a gentler adhesive drape for wound therapy
This trial compares a special adhesive drape (the switchable one) with the standard drape during negative pressure wound therapy (a treatment that uses suction to help heal wounds after surgery). The goal is to see if the new drape causes less pain when removed.
Los Angeles, CaliforniaAges 18 years+ - NCT07181447Recruiting
Light test for muscle-based pelvic pain
This study uses a light device on the skin to detect muscle trigger points in women with long-term pelvic pain. The goal is to see if near-infrared spectroscopy (NIRS) can help diagnose myofascial pelvic pain more easily.
Los Angeles, CaliforniaAges 18 years+
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Pain trials in other cities
Where these studies are running near Los Angeles
Institutions with a site for the recruiting pain studies listed above.
- University of California, Los Angeles (UCLA) · 11 studies
- Cedars-Sinai Medical Center · 3 studies
- University of Southern California · 2 studies
- All South Bay Footcare/Podiatry Group, Inc.
- American Institute of Research
- Angel City Research Inc
- Central Recruiting Site
- Children's Hospital Los Angeles
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in California.
Common questions
- Are there pain clinical trials near Los Angeles?
- Yes. We're currently tracking 87 recruiting pain studies with a site near Los Angeles, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Los Angeles?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Los Angeles to take part?
- Not necessarily. These studies have a site near Los Angeles, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Los Angeles regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.