Clinical trials
Pancreatic Adenocarcinoma clinical trials
Below are recruiting pancreatic adenocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06937567RecruitingEarly Phase 1
CDH17 car-t therapy for advanced solid tumors
This trial tests a new treatment called CDH17 CAR-T for people with advanced solid tumors like colorectal, stomach, pancreatic, or bile duct cancer. It is for patients who have tried other treatments without success. The therapy uses your own immune cells, modified to target a protein called CDH17 found on some cancer cells.
Hangzhou, ZhejiangAges 18–70 - NCT07481383RecruitingPhase 1
Implant device for chemo delivery in advanced pancreatic cancer
This trial tests an implantable device that delivers chemotherapy (gemcitabine) directly to pancreatic tumors. It may offer a new treatment option for people with non-metastatic, advanced pancreatic cancer that cannot be surgically removed.
Ann Arbor, MichiganAges 18 years+ - NCT07659639Recruiting
A blood test using light to find pancreatic cancer early
This trial tests a new blood test that uses tiny particles and a laser to find signs of pancreatic cancer earlier. It may help people with pancreatic ductal adenocarcinoma (PDAC) or intraductal papillary mucinous neoplasms (IPMN), a type of cyst that can become cancer.
Rome, ItalyAges 18 years+ - NCT04665947RecruitingEarly Phase 1
Imaging and targeted drug for pancreatic cancer using special radiation
This early study tests a two-step approach: a special PET/CT scan to find pancreatic cancer, followed by a targeted radiation medicine to attack it. It may help researchers learn whether this targeted approach is safe and able to reach pancreatic tumors after standard treatment.
Sacramento, CaliforniaAges 18 years+ - NCT06330441Recruiting
Pancreatic cancer screening for high-risk groups
This study screens people at high risk for pancreatic cancer using imaging tests. It aims to catch cancer early in those with certain genetic conditions or strong family history.
BrnoAges 18 years+ - NCT05132244Recruiting
Checking and treating blood sugar in pancreatic cancer
This trial tests a plan to monitor and manage blood sugar in people with pancreatic ductal cancer who are starting a specific chemotherapy regimen (FOLFIRINOX). The goal is to prevent or address high blood sugar during treatment, which may help people stay on therapy safely.
Vancouver, British ColumbiaAges 18 years+ - NCT07340151Recruiting
Surgery for limited liver or lung pancreatic cancer spread
This trial tests whether removing or ablating limited liver or lung tumors from pancreatic cancer that has not spread elsewhere, along with a specific chemotherapy (NALIRIFOX), can help patients. It is for people who have not had any previous cancer treatment.
San Antonio, TexasAges Any age - NCT03492671RecruitingPhase 2
Two chemotherapy drugs plus radiation before pancreatic surgery
This trial tests whether giving two already-approved chemotherapy drugs and radiation before surgery works better for localized pancreatic cancer. It’s meant for people whose cancer looks removable by surgery and who haven’t had prior pancreatic cancer treatment.
Loma Linda, CaliforniaAges 18 years+ - NCT06576115RecruitingPhase 2
Combination therapy with device for metastatic pancreatic cancer
This trial tests whether adding a non-invasive device that uses low-level radio waves to standard chemotherapy (gemcitabine and nab-paclitaxel) can help people with pancreatic cancer that has spread to other parts of the body.
Clarkston, MichiganAges 18 years+ - NCT01954992RecruitingPhase 3
Glufosfamide vs 5-FU for metastatic pancreatic cancer after gemcitabine
This study compares two chemotherapy drugs—glufosfamide and 5-FU—in people with pancreatic cancer that has spread and got worse after gemcitabine. It aims to see which option works better as a “second-line” treatment.
Whittier, CaliforniaAges 18 years+ - NCT07232810Recruiting
Surgery With Extra Tissue Removal for Pancreatic Head Cancer
This study tests whether removing extra tissue around the pancreas during a standard surgery improves outlook for people with pancreatic head cancer. You may qualify if you have this type of cancer and are planning surgery without prior chemotherapy or radiation.
Minya, Minya GovernorateAges 18–80 - NCT06861088RecruitingPhase 3
Kinisoquin for preventing blood clots in pancreatic cancer
This trial tests whether an investigational drug called Kinisoquin™ can help prevent blood clots in people with advanced pancreatic cancer who are starting their first chemotherapy. It may be a good option if you are looking for extra protection against clots during treatment.
Ventura, CaliforniaAges 18 years+ - NCT04793633Enrolling by invitation
Testing a noninvasive way to collect pancreatic cells early
This study tests LINFU™, a noninvasive method to collect pancreatic cells to help detect pancreatic cancer earlier. You may be invited if you’re at higher risk or you have concerning symptoms and planned pancreas/bile testing (like EUS or CT).
Sarasota, FloridaAges 18–90 - NCT07324096Recruiting
Screening for pancreatic cancer in people with new diabetes
This study screens people with recent diabetes who are at high risk for pancreatic cancer. It uses a CT scan to find cancer early, when it may be easier to treat.
Rochester, MinnesotaAges 50–85 - NCT07226154Recruiting
Predicting chemo response in pancreatic cancer
This study looks at blood samples to see if we can predict how well pancreatic cancer responds to chemotherapy before surgery. It aims to help doctors choose the best treatment for each patient.
Duarte, CaliforniaAges 18 years+ - NCT07644559RecruitingPhase 2
VS-7375 for KRAS G12D pancreatic cancer
This study tests a new drug called VS-7375, combined with cetuximab, for pancreatic cancer patients whose tumors have a specific genetic mutation called KRAS G12D. The goal is to see if this combination can shrink tumors and help patients live longer.
Los Angeles, CaliforniaAges 18 years+ - NCT07199764RecruitingPhase 2
Maintenance therapy using combination immunotherapy for pancreatic cancer
This trial tests a combination of immunotherapy drugs (targeting CD40 and other immune cells) as a maintenance treatment for people with advanced pancreatic cancer that has not grown or has shrunk after initial chemotherapy. The goal is to see if this approach can keep the cancer from progressing longer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05296421Recruiting
Biopsy study during pancreatic cancer surgery to guide treatment
This study looks at specific body chemistry pathways in pancreatic cancer tissue to better understand what may help treatment work. If you are having pancreatic surgery, the researchers will take extra small tissue samples during the operation to study tumor and normal tissue.
Livingston, New JerseyAges 18 years+ - NCT04575363Recruiting
Testing a blood marker to predict pancreatic cancer outcomes
This study looks at a test called RPSA to see if it can help predict how pancreatic cancer may turn out. It includes people being treated at Reims University Hospital for pancreatic tumors that can be removed (or may become removable).
ReimsAges 18 years+ - NCT07683845Recruiting
Using a tumor model to predict chemo response in pancreatic cancer
This trial tests a personalized approach by growing a miniature model of your tumor from a tissue sample. The goal is to see if this model can predict which chemotherapy will work best for you before you start treatment.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06079346RecruitingPhase 2/Phase 3
New drug with chemotherapy for advanced pancreatic cancer
This trial tests a new drug called OT-101 combined with a standard chemotherapy regimen (mFOLFIRINOX) for people with advanced pancreatic cancer that has spread or cannot be removed. The goal is to see if the combination can help shrink or control the cancer better than chemotherapy alone.
Detroit, MichiganAges 18 years+ - NCT05257993RecruitingPhase 1/Phase 2
Pancreatic cancer trial testing JPI-547 with standard chemo
This study tests whether adding JPI-547 to standard chemotherapy (modified FOLFIRINOX or gemcitabine with nab-paclitaxel) is safe and tolerable in people with advanced pancreatic cancer. If it works, it may improve treatment options for cancers that have spread or cannot be removed with surgery.
Gyeonggi-doAges 19–79 - NCT07255404RecruitingPhase 2
Testing pumitamig with chemotherapy for untreated pancreatic cancer
This trial tests an experimental drug called pumitamig combined with standard chemotherapy for people with advanced pancreatic cancer that has spread and has not been treated yet. The goal is to see if this combination is safe and effective.
Bedford ParkAges 18 years+ - NCT04969731RecruitingPhase 3
Immune cell therapy plus gemcitabine after pancreas surgery
This Phase 3 trial tests whether adding an immune cell therapy (Immuncell-LC) to the standard chemotherapy drug gemcitabine helps people with resectable pancreatic cancer after surgery. It aims to improve safety and outcomes like preventing the cancer from coming back.
Seoul, Daehak-ro, Jongno-guAges 19–80
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Common questions
- Are there clinical trials for pancreatic adenocarcinoma?
- Yes. Clin2 currently lists 348 recruiting pancreatic adenocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pancreatic adenocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pancreatic adenocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pancreatic Ductal Adenocarcinoma
- Pancreatic Ductal Adenocarcinoma (PDAC)
- Metastatic Pancreatic Adenocarcinoma
- Locally Advanced Pancreatic Adenocarcinoma
- Metastatic Pancreatic Ductal Adenocarcinoma
- Locally Advanced Pancreatic Ductal Adenocarcinoma
- Borderline Resectable Pancreatic Adenocarcinoma
- Borderline Resectable Pancreatic Ductal Adenocarcinoma
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.