VS-7375 for KRAS G12D pancreatic cancer
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This study tests a new drug called VS-7375, combined with cetuximab, for pancreatic cancer patients whose tumors have a specific genetic mutation called KRAS G12D. The goal is to see if this combination can shrink tumors and help patients live longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Pancreatic cancer confirmed by biopsy or surgery with the specific KRAS G12D genetic mutation
- Measurable tumors that can be tracked on imaging scans
- Good overall health and ability to care for yourself (ECOG score 0 or 1)
- Normal kidney, liver, and heart function
- No other RAS gene mutations besides KRAS G12D
- No prior treatment with other RAS-targeting drugs
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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