Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06657274Recruiting
Digital brain training for early memory problems
This study tests a smart digital program (app or computer-based) to help with memory, thinking, and daily life in people with early Parkinson's, mild cognitive impairment, or early memory concerns. It uses brain stimulation (TMS) along with cognitive exercises.
Brescia, ITAges 18–85 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT07314190Enrolling by invitation
Blood tests for brain diseases and mental health conditions
This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.
BarcelonaAges 18 years+ - NCT06438419Recruiting
Brain activity in Parkinson's during movement with DBS
This study records brain activity during movement in people with Parkinson's who have a special deep brain stimulation (DBS) device. It aims to understand how brain rhythms relate to movement, which could improve future treatments.
BordeauxAges 18–75 - NCT02060695Recruiting
Study links Parkinson symptom ups and downs over time
This study looks at how changes in movement symptoms and non-movement symptoms happen together in people with early Parkinson disease. It may help doctors better understand what triggers symptom “ups and downs” and how to time treatment or monitoring.
SeoulAges Any age - NCT03508986Recruiting
Parkinson’s family registry for people with Parkinson’s
This trial is a research registry that collects health and family information from people with Parkinson’s disease (and sometimes their close relatives). It may help doctors better understand how Parkinson’s runs in families.
Changsha, HunanAges Any age - NCT03508960Recruiting
Parkinson’s disease registry for people with early onset
This study is a registry that collects information from people with Parkinson’s disease (PD) to better understand the condition, especially in people whose symptoms started by age 50. It may help researchers learn which factors matter most for early-onset PD.
Changsha, HunanAges Up to 50 years - NCT03523104Recruiting
Registry for Parkinson’s with LRRK2 gene variants
This study is a registry that collects information from people with Parkinson’s who have specific LRRK2 gene changes. It helps researchers understand how this genetic form of Parkinson’s behaves over time.
Changsha, HunanAges Any age - NCT03523052Recruiting
People with Parkinson’s and SNCA gene changes
This registry study enrolls people who have Parkinson’s disease and carry certain SNCA gene changes. It aims to better understand how these genetic changes relate to Parkinson’s, which can guide future research and care.
Changsha, HunanAges Any age - NCT03523065Recruiting
Parkinson’s registry for people with GBA gene changes
This registry collects information about people with Parkinson’s who have specific changes in the GBA gene. The goal is to better understand how these gene changes affect Parkinson’s and support future research.
Changsha, HunanAges Any age - NCT03992625Recruiting
Deep brain stimulation study for Parkinson’s, tremor, or dystonia
This trial studies outcomes after deep brain stimulation (a treatment that uses implanted electrodes) for people with Parkinson’s disease, essential tremor, or dystonia. It may help doctors understand who benefits most and how outcomes change after treatment.
St Louis, MissouriAges Any age - NCT03887663Recruiting
Chinese Parkinson’s disease patient registry
This study is a registry that collects information from people with Parkinson’s disease to better understand the condition. You may help researchers learn about patterns of symptoms and care over time.
Changzhi, HunanAges Any age - NCT05767151Recruiting
Newly diagnosed Parkinson’s study for early disease
This study looks at people newly diagnosed with Parkinson’s disease, before starting Parkinson’s medicines, to better understand early illness. It may help researchers identify patterns that could guide future treatments.
Changsha, HunanAges 30–75 - NCT06062693Recruiting
Home Hand Training with Sensors for Better Dexterity
This study tests a new home-based hand training system using sensors to help improve hand movement and dexterity in people with Parkinson's, multiple sclerosis, or stroke. It also includes healthy volunteers for comparison.
LucerneAges 18–99 - NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT07863180RecruitingPhase 1/Phase 2
Tributyrin for progressive supranuclear palsy
This trial tests a supplement called tributyrin to see if it can help people with progressive supranuclear palsy (PSP), a condition that affects movement and balance. The study is done virtually, so you can participate from home with a caregiver's help.
Ann Arbor, MichiganAges 45 years+ - NCT07846007Recruiting
Ultrasound brain stimulation for Parkinson's disease
This study tests a non-invasive ultrasound treatment that gently stimulates a small part of the brain to see if it can improve Parkinson's symptoms like movement and stiffness. It may be an option for people who have not had brain surgery yet.
Toronto, OntarioAges 18–90 - NCT07850674Recruiting
Spinal stiffness and fear of movement in Parkinson's
This study looks at how Parkinson's disease affects neck and back movement, stiffness, and fear of movement, in relation to jaw joint problems. The results may help improve therapies that target flexibility and quality of life.
HatayAges 35–75 - NCT07835308RecruitingEarly Phase 1
Smart tuning of brain stimulation for better walking
This study is testing a new way to adjust deep brain stimulation (DBS) settings to improve walking in people with Parkinson's disease. If you have DBS and can walk with stimulation off, this trial may help fine-tune your treatment to improve your gait.
Minneapolis, MinnesotaAges 18 years+ - NCT06608875Recruiting
Personalized stimulation to improve walking and balance
This trial tests a way to help people with Parkinson's disease improve their walking and balance by using personalized stimulation. If you have trouble with walking or balance and are already planning rehab at cereneo, you might be able to join.
Zurich, Canton of ZurichAges 18 years+ - NCT04635436Recruiting
Split-walking training for one-sided leg weakness when walking hurts
This trial tests whether a “split gait” walking training method can improve walking balance and how you move when you have one-sided leg problems and pain or limitations when walking. It may help reduce walking difficulties by training your stepping pattern safely.
Milan, MIAges 18–70 - NCT05822258Recruiting
Tracking freezing while walking in Parkinson’s using motion sensors
This study tests motion-sensor devices (small inertial measurement units) to detect moments when walking suddenly “freezes” in Parkinson’s disease. If you have freezing episodes, it may help researchers measure them more accurately and support better monitoring.
Rennes, Brittany RegionAges 18 years+ - NCT07701785Recruiting
Brain stimulation study for Parkinson's with mild memory issues
This trial tests a type of brain stimulation called iTBS on an area of the brain that may help with thinking and memory problems in people with Parkinson's disease and mild cognitive impairment. If you qualify, you and your caregiver would take part in sessions and answer questions about your daily life.
Charleston, South CarolinaAges 50–85 - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.