Clinical trials
Parkinson s Disease clinical trials
Below are recruiting parkinson s disease clinical trials, each written for real people, not researchers. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT07752355Recruiting
Parkinson's subtypes and causes in young onset disease
This study looks at different types of Parkinson's disease, especially in people diagnosed before age 50. It involves a small skin biopsy to help understand what causes the disease.
New York, New YorkAges 18 years+ - NCT07567794Recruiting
Gut-Brain Connection Study in Parkinson's Disease
This research examines how the gut and brain are connected in Parkinson's disease and aims to better understand the disease. You'd participate in visits and tests over three years, including some involving your digestive system.
Stanford, CaliforniaAges 21–80 - NCT07630545RecruitingPhase 1
Testing a new drug for Parkinson's disease
This study tests an experimental drug, MTX325, in people with Parkinson's disease. The goal is to see if it is safe and how the body processes it, which may lead to new treatment options.
AdelaideAges 18–75 - NCT07568067Recruiting
Accelerated Brain Stimulation for Parkinson's Disease
This trial tests a new type of brain stimulation (called temporal interference stimulation) targeted at specific brain regions to help improve Parkinson's disease symptoms. Researchers will use MRI imaging and behavioral assessments to see if this approach can reduce movement problems and improve quality of life.
Guangzhou, GuangdongAges Up to 85 years - NCT05357612RecruitingPhase 4
PET scan study for brain serotonin in neurodegenerative diseases
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
Nashville, TennesseeAges 50–85 - NCT03019757Recruiting
Testing ways to tell dementia causes apart
This study looks at how to distinguish Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease when someone has memory and thinking problems. It may help doctors choose the most accurate diagnosis and treatment path for the right condition.
Columbus, OhioAges 18 years+ - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT04101968Recruiting
Study of GBA changes in Parkinson’s using multiple tests
This study looks at people with Parkinson’s who carry a specific genetic change in the GBA gene. It uses several tests (including brain scans) to understand the disease better and may help guide future treatments.
Portland, OregonAges 18–80 - NCT04735458Recruiting
Brain network study for Parkinson’s or essential tremor
This study looks at how “inhibitory control” brain networks work in people with Parkinson’s disease or essential tremor. If you are eligible for surgery and can do the study tasks, your results may help researchers better understand movement disorders and guide future treatments.
Birmingham, AlabamaAges 18 years+ - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85 - NCT04804202Recruiting
Virtual cycling program for people with Parkinson disease
This study tests whether a virtual, guided stationary bike exercise program is safe and helpful for people with Parkinson disease. It may help improve movement and fitness by letting you ride at home or in a controlled setting while using visual and audio guidance.
Newark, New JerseyAges 45–75 - NCT04941326Recruiting
Spinal mobilization for breathing in Parkinson’s disease
This study tests whether a hands-on therapy to the spine can improve breathing measures in people with Parkinson’s disease. If you qualify, you would receive spinal mobilization and have your breathing assessed to see if it helps.
BoluAges 50–85 - NCT04997642Recruiting
Parkinson’s patient database for memory and movement tracking
This study builds a research database of people who receive care for Parkinson’s disease, including those with mild memory problems or dementia. It aims to collect consistent information that researchers can use to better understand Parkinson’s and related thinking changes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05348837Recruiting
Two-week sleep tracking for people with Parkinson’s
This study uses a wristband and a headband to track your sleep for two weeks. It’s meant to better understand sleep patterns in Parkinson’s, and may require temporarily changing your evening medication timing.
Aurora, ColoradoAges 18–80 - NCT05516719Recruiting
Study tracking I2BS in Parkinson’s over time
This study follows people with Parkinson’s to see how “I2BS” changes over time using special brain scans and other tests. It may help researchers better understand Parkinson’s and improve how it’s measured in future trials.
Exeter, DevonAges 25 years+ - NCT05516732Recruiting
Testing serotonin activity in the brain in people with Parkinson’s
This study uses special scans to measure how serotonin is released in parts of the brain involved in movement in Parkinson’s disease. It may help researchers understand disease changes and the role of serotonin systems in movement problems.
Exeter, DevonAges 25–85 - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT05603715RecruitingPhase 2
Pyridostigmine to help constipation in Parkinson’s
This trial tests whether pyridostigmine can improve constipation symptoms in people with Parkinson’s disease. If you have Parkinson’s and functional constipation (with infrequent bowel movements), this study may offer a new medication option and closely track your bowel function.
Burlington, VermontAges 18 years+ - NCT05748028Recruiting
Testing treatment for pain and nerve symptoms in Parkinson’s
This study looks at pain and “autonomic” (automatic body) symptoms in people with Parkinson’s disease or a related condition called multiple system atrophy. It aims to understand what helps and to learn more about these symptoms in different types of Parkinson-like illnesses.
Telese Terme, BeneventoAges 18 years+ - NCT05778617RecruitingPhase 3
Ambroxol to Slow Parkinson’s Disease Progression
This trial studies whether ambroxol (or a placebo) can slow the progression of Parkinson’s disease. It may help by aiming to change how the disease develops over time.
BirminghamAges 35–75 - NCT05864157Recruiting
Targeted training to improve walking in Parkinson’s disease
This study tests a targeted motor training approach to improve walking (gait) in people with Parkinson’s disease. You may be considered if your walking is affected but you can already walk steadily for 10 minutes without help.
Chapel Hill, North CarolinaAges 50–80 - NCT05884944Recruiting
Osteopathic massage study for leg muscle in Parkinson’s disease
This trial studies whether osteopathic manipulative medicine (gentle hands-on treatment) can change how leg muscles work in people with Parkinson’s disease. It may help with leg pain, cramping, or walking problems caused by Parkinson’s.
Old Westbury, New YorkAges 18 years+ - NCT05908279Recruiting
Walking and gait study in people with Parkinson’s disease
This trial studies walking patterns and how walking is controlled in people with Parkinson’s disease. It may help researchers understand movement control and improve future therapies by comparing walking ability and patterns.
Louvain-la-NeuveAges 18–99
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Common questions
- Are there clinical trials for parkinson s disease?
- Yes. Clin2 currently lists 739 recruiting parkinson s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.