Clinical trials
Pediatric Patients clinical trials
Below are recruiting pediatric patients clinical trials, each written for real people, not researchers. We’re tracking 347 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05820802Recruiting
Studying immune cells in children during surgery
This study looks closely at immune cells in children while they are having surgery under general anesthesia using a specific muscle-relaxing medicine (rocuronium). It may help researchers understand how immune systems respond around the time of surgery and anesthesia.
SeoulAges 2–18 - NCT05366218RecruitingPhase 1/Phase 2
Tafasitamab for kids with high-risk B-cell leukemia after relapse
This Phase 1/2 study tests tafasitamab in children and teens with B-lineage acute lymphoblastic leukemia (ALL) that has come back or did not respond. It is mainly for patients with specific high-risk leukemia changes and/or leukemia markers that stay after stem cell transplant or CAR T-cell therapy.
Freiburg im Breisgau, Baden-WurttembergAges 3–18 - NCT05511987Recruiting
Thopaz+ digital chest tube vs standard drainage in kids
This study compares a digital chest tube drainage system (called Thopaz+) to the usual (analog) drainage in children who need a chest tube. The goal is to see if the digital system works better or is easier for recovery after a pneumothorax or lung surgery.
Oklahoma City, OklahomaAges birth–17 years - NCT04908709Recruiting
MRI-guided proton therapy for high-grade brain tumors in children
This study looks at how metabolism in a child’s brain tumor changes during proton therapy, using special MRI scans. It may help doctors better understand treatment response and tailor care for pediatric high-grade gliomas.
Atlanta, GeorgiaAges Up to 21 years - NCT05019716RecruitingPhase 1/Phase 2
Adding ZEN003694 to chemo for NUT cancer
This early-phase study tests whether adding ZEN003694 to standard chemotherapy (cisplatin/etoposide or carboplatin/paclitaxel) is safe and can help control NUT carcinoma. It enrolls people ages 12–17 and adults, including some patients whose cancer has spread or can’t be safely removed.
Los Angeles, CaliforniaAges 12 years+ - NCT03431064Recruiting
Ultrasound test during surgery to predict fluid needs in children
This study looks at a specific breathing maneuver done while your child is on a ventilator during surgery, and uses ultrasound-related measurements to predict whether they’ll need extra fluids. If it works, it may help doctors give the right amount of fluid and avoid problems from too little or too much.
Boston, MassachusettsAges Up to 17 years - NCT04629469Recruiting
Two types of MRI scans in children
This study compares two MRI scan settings (a lower and higher magnetic field) in children to see how well they work for pediatric patients. It may help doctors choose the best MRI approach for kids without changing any care beyond the scan itself.
Kansas City, MissouriAges birth–22 years - NCT02852213RecruitingPhase 1
Dose-check study for children with AADC deficiency using brain surgery
This Phase 1 trial tests how safe different treatment doses are for children with AADC deficiency, using MRI-guided brain surgery. It may help improve movement and developmental progress after standard medicines did not work well enough.
San Francisco, CaliforniaAges 2 years+ - NCT06801223RecruitingPhase 1
Testing sulbactam-durlobactam for children with ABC infection
This trial tests a new combination of antibiotics (sulbactam-durlobactam) for children with a serious infection caused by Acinetobacter bacteria. The goal is to see if this treatment is safe and works well for kids.
Los Angeles, CaliforniaAges 1 day–18 years - NCT02446431RecruitingEarly Phase 1
Low-dose cancer medicine for children with sarcoma at high risk
This early-phase study tests a continuous, low-dose (“metronomic”) cancer medicine to help delay cancer coming back in children and young adults with certain sarcomas. You must have finished first-line treatment and currently be in remission, starting the study soon after treatment ends.
Long Beach, CaliforniaAges 1–31 - NCT07105254RecruitingPhase 2
Roflumilast foam study for children with vitiligo
This study tests a medicated foam (Roflumilast) in children with non-segmental vitiligo to see if it can improve skin color on the face and body. It is for patients aged 2 to 17 with small patches and at least some pigmented hair in the face patches.
Dallas, TexasAges 2–18 - NCT07451470Recruiting
Comparing two airway devices for stomach air in children during short surgeries
This trial compares two devices used to help children breathe during surgery (LarySeal Pro and Ambu AuraGain). It measures how much air gets into the stomach, which can cause discomfort. It is for children aged 6–12 having short elective surgeries (1 hour or less).
Cairo, Cairo GovernorateAges 6–10 - NCT07357051RecruitingPhase 3
Flu treatment study for children ages 2 to 12
This trial tests a new oral medicine (JKN2301) for children with the flu. It aims to see if the medicine is safe and works well to treat flu symptoms like fever and cough.
Guangzhou, GuangdongAges 2–11 - NCT06609928RecruitingPhase 1
CAR T cell therapy for children with relapsed AML that has FOLR1
This trial tests a special immune cell treatment (CAR T cells) that target a protein called FOLR1 found on some AML cells. It is for children aged 6 or younger whose leukemia has come back or not responded to treatment.
Seattle, WashingtonAges Up to 6 years - NCT06381570RecruitingEarly Phase 1
Vinblastine and tovorafenib for recurring pediatric low-grade glioma
This trial is testing a combination of two drugs, vinblastine and tovorafenib, for children and young adults (up to age 25) whose low-grade glioma has come back or worsened after prior treatment. It is for people whose tumor has a specific change in a gene called BRAF or CRAF.
Toronto, OntarioAges birth–25 years - NCT06386718Recruiting
Ultrasound of hand arteries in children
This study uses ultrasound to look at the blood vessels in the hands of children before they have surgery. It helps doctors understand hand blood flow better, which can make procedures safer.
AnkaraAges Up to 10 years - NCT07029230Recruiting
Blood test during heart surgery to predict heart failure in kids
This study looks at a substance called sST2 in the blood of children having heart surgery. The goal is to see if sST2 levels can help doctors predict heart failure after surgery.
Zurich, Canton of ZurichAges Up to 18 years - NCT05905926Enrolling by invitationPhase 3
Tenapanor safety study for teens with constipation-predominant IBS
This trial checks the safety of tenapanor in children and teens (ages 6 to under 18) with IBS-C. It is only for people who finished a previous related study and agreed to continue follow-up.
Foley, AlabamaAges 6–18 - NCT06706674RecruitingPhase 3
Testing lumateperone for irritability in teens with autism
This study tests an investigational medication called lumateperone to see if it can reduce irritability in children and teens with autism. It is for teenagers aged 13–17 whose irritability is causing significant problems.
Little Rock, ArkansasAges 5–17 - NCT07572435Recruiting
Remote Heart Exercise Program for Kids With Heart Surgery
This study tests whether kids aged 8–18 who had complex heart surgery can safely improve their fitness and well-being using exercise activities at home through a mobile app or video. The goal is to help them become more active after surgery.
SeoulAges 8–18 - NCT06714695Recruiting
Testing a mouthwash for black stains on kids' teeth
This trial tests if a special mouthwash made from chitosan (a natural substance from shellfish) can prevent black stains from coming back on children's teeth. Kids will use the mouthwash and be checked over 18 weeks to see if it works.
Cairo, Cairo GovernorateAges 6–12 - NCT06706375Recruiting
Comparing two types of penile nerve blocks for child circumcision
This study tests two ways of numbing the penis before circumcision in children. The goal is to see which method works better and causes less discomfort.
Lausanne, Canton of VaudAges Up to 17 years - NCT06344091RecruitingPhase 4
Study of a long-lasting numbing medicine for children having orthopedic surgery
This trial tests a long-lasting numbing medicine (bupivacaine liposome injection) given during surgery to help control pain in children. It may reduce the need for other painkillers after orthopedic surgery.
Guangzhou, GuangdongAges 6–17 - NCT07288580RecruitingPhase 1/Phase 2
Gene therapy for children with inherited deafness
This trial tests an injection called EHT102 for children who have severe or profound hearing loss due to mutations in the Otoferlin gene. The goal is to see if the treatment can restore or improve hearing.
Shanghai, Shanghai MunicipalityAges 1–17
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Common questions
- Are there clinical trials for pediatric patients?
- Yes. Clin2 currently lists 347 recruiting pediatric patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.