Clinical trials
Pelvic Pain Syndrome clinical trials
Below are recruiting pelvic pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT05513417Enrolling by invitation
Digital pelvic health program for women with pelvic pain
This study tests a digital (phone/app-based) program to help women with pelvic pain or pelvic health symptoms. It may help by guiding pelvic-focused exercises and care, especially if you’re recovering from pelvic surgery or managing ongoing symptoms.
Draper, UtahAges 18–99 - NCT05344716Recruiting
Erbium laser treatment for urethral pain in women
This trial tests whether an erbium:YAG laser can reduce urethral and lower pelvic pain that has lasted for at least 6 months. It may help people whose pain has not improved with at least one non-surgical treatment.
Frauenfeld, ThurgauAges 18 years+ - NCT05127616Recruiting
Trial for chronic pelvic pain: CBT vs education/support
This study tests whether structured talking therapy (CBT) or education/support helps reduce chronic pelvic pain problems in adults. It compares two approaches over time and uses symptom diaries and follow-up check-ins to see which works better.
Los Angeles, CaliforniaAges 18–70 - NCT03794466Recruiting
Study pain relief after blocking gonadal veins for pelvic congestion
This study looks at how much pelvic pain improves after a procedure called gonadal vein embolization (blocking problem veins). It mainly applies to people diagnosed with pelvic congestion syndrome caused by venous (vein) problems, treated during a specific time window.
Kansas City, KansasAges 18 years+ - NCT00499317Recruiting
Genetic study of chronic pelvic pain and bladder symptoms
This study looks for genetic (inherited) factors behind chronic pelvic pain and related urinary and sexual symptoms. You may be able to help researchers by providing a few samples and answering short questions, which could improve understanding of these conditions.
Boston, MassachusettsAges Any age - NCT07734051Enrolling by invitation
Mobilization for kneecap pain
This trial tests if adding a groin-area mobilization to foot mobilization helps with kneecap (patellofemoral) pain. It may be for you if you have one-sided kneecap pain for at least 3 months, especially when climbing stairs, squatting, or sitting for long periods.
Fāqūs, SharkeyaAges 18–40 - NCT06729151Recruiting
Botox vs. standard care for bladder pain and sexual health
This study compares the effect of Botox injections into the bladder versus standard care (without injections) on sexual function in women with bladder pain syndrome. It aims to see if Botox can improve both pain and sexual health.
Bethesda, MarylandAges 18–99 - NCT06204874Recruiting
Nerve stimulation for bladder pain in women
This trial tests a new nerve stimulation approach for women with bladder pain syndrome. It aims to find a gentler way to reduce pain and urgency without surgery.
Bethesda, MarylandAges 18 years+ - NCT06908200Recruiting
Radiofrequency for chronic pelvic pain with myofascial syndrome
This trial compares radiofrequency treatment, myofascial therapy, and no treatment to see which is most effective for women with chronic pelvic pain caused by tight or tender pelvic floor muscles. It aims to help reduce pain and improve quality of life.
BarcelonaAges 18 years+ - NCT07854041Recruiting
Release techniques for kneecap pain
This study tests two hands-on therapies to ease kneecap pain. It may help if your pain has lasted at least three months and gets worse with stairs, running, or sitting for a long time.
Lahore, Punjab ProvinceAges 15–40 - NCT07735156Recruiting
Treating Pelvic Pain with Vein Blockage
This study tests a minimally invasive procedure that blocks abnormal veins in the pelvis to relieve long-term pelvic pain. It may help women with pelvic congestion syndrome.
Sohag, Sohag GovernorateAges 17–55 - NCT06840314Recruiting
Vibration vs traditional therapy for painful sex
This trial compares a vibrating vaginal device to standard therapy for women with pain during sex. It aims to find a more effective and comfortable treatment option.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06413277Recruiting
ECAP-controlled spinal cord stimulation for chronic pelvic pain
This trial tests a new type of spinal cord stimulator that uses closed-loop technology to treat chronic pelvic pain caused by a known injury. It may be an option if your pain is severe and hasn't responded to other treatments.
New York, New YorkAges 18 years+ - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06560294Recruiting
Glue injection vs watchful waiting for pelvic congestion syndrome
This trial compares a new glue injection treatment (embolization) with no active treatment for pelvic congestion syndrome. It aims to see if the glue procedure reduces pelvic pain and varicose veins better than just monitoring symptoms.
Tanta, ElGharbiaAges 30–50 - NCT06394830RecruitingPhase 2
Testing VNX001 for bladder pain syndrome
This study tests a new treatment (VNX001) for people with interstitial cystitis or bladder pain syndrome (IC/BPS). You must have already taken part in an earlier study of this drug to join. The goal is to see if it safely reduces bladder pain.
Tucson, ArizonaAges 18 years+ - NCT06995287RecruitingPhase 3
Botulinum toxin injection for severe period pain
This trial tests whether injecting botulinum toxin into the uterine muscle during a hysteroscopy can reduce severe period pain or chronic pelvic pain that hasn't improved with standard treatments. It may be an option for women who have tried hormonal therapy and pain relievers without success.
Aix-en-ProvenceAges 18 years+ - NCT07437924Enrolling by invitation
Bruxism and pelvic floor health in young women
This study looks at whether teeth grinding (bruxism) is linked to pelvic floor muscle function in young women. If you are 18–30 and either grind your teeth or do not, you may help researchers understand this connection.
KonyaAges 18–30 - NCT06988319RecruitingPhase 1
Psilocybin for chronic pelvic pain in women: a pilot study
This trial tests whether psilocybin (a psychedelic drug) can help women with long-term pelvic pain that hasn't gotten better with standard treatments. The goal is to see if it's possible and safe to use this approach in a future larger study.
Portland, OregonAges 18–45 - NCT07494864Recruiting
Urinary tract health and microbiome study
This study looks at how bacteria and the immune system affect the lower urinary tract. It includes healthy volunteers and people with various urinary conditions, like infections or bladder pain.
Zurich, Canton of ZurichAges 18 years+ - NCT07679074Recruiting
Samphire guided care program for women's mood and brain fog
This 12-week program tests a mobile app and gentle brain stimulation device designed to help women manage mood and thinking problems linked to their menstrual cycle, perimenopause, or menopause. It aims to improve day-to-day well-being, work productivity, and overall quality of life.
San Francisco, CaliforniaAges 18–65 - NCT04845217RecruitingPhase 1/Phase 2
Peppermint oil for bladder pain in women
This trial tests whether peppermint oil can reduce symptoms of interstitial cystitis (also called bladder pain syndrome). It’s mainly looking at safety and early signs it may help your bladder discomfort.
Louisville, KentuckyAges 18–65
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Common questions
- Are there clinical trials for pelvic pain syndrome?
- Yes. Clin2 currently lists 62 recruiting pelvic pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pelvic pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pelvic pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.