Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06774235RecruitingPhase 3
Interferon gamma to prevent infections in ICU patients
This trial tests if a drug called interferon gamma can help prevent new infections in ICU patients with a weakened immune system. It may help people who have been in the ICU for at least a week and have had multiple organ failure.
AngersAges 18 years+ - NCT06776731Recruiting
Does extra oxygen during rehab help lung disease patients?
This study tests whether breathing extra oxygen during outpatient pulmonary rehabilitation helps people with COPD. Participants will have their oxygen levels checked during exercise to see if extra oxygen improves their rehab results.
Winterthur, Canton of ZurichAges 18 years+ - NCT06771791RecruitingPhase 3
Apple oral immunotherapy trial for birch pollen and apple allergy
This trial tests if eating small amounts of raw apple can help people with birch pollen allergy who also have mouth itching or swelling from apples. You will be given gradually increasing doses of apple to see if your allergy improves.
Strasbourg, FranceAges 18 years+ - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT06761066Enrolling by invitation
Testing NVP-NK4146 for mild cognitive impairment due to Alzheimer's
This study tests a new medicine, NVP-NK4146, for people with mild cognitive impairment (MCI) due to Alzheimer's disease. The goal is to see if it can help slow down memory and thinking problems.
SeoulAges 60 years+ - NCT06767527RecruitingPhase 3
AK112 plus chemo for first-line triple-negative breast cancer
This trial tests a new immunotherapy drug called AK112 combined with chemotherapy (nab-paclitaxel) for people with advanced triple-negative breast cancer who haven't had treatment yet. The goal is to see if AK112 works better than a placebo at shrinking tumors and helping people live longer.
BeijingAges 18–75 - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT06762964RecruitingPhase 2
Dapagliflozin for Failing Fontan Circulation
This study tests whether a medication called dapagliflozin (a pill for heart failure) can help people with a Fontan circulation who feel short of breath. It aims to improve symptoms and quality of life.
Rochester, MinnesotaAges 18 years+ - NCT06768944RecruitingPhase 2
Psilocybin and Subjective Experience Study
This study looks at how psilocybin affects people's subjective experience. It aims to understand the mind-altering effects of this psychedelic compound in healthy volunteers.
Calgary, AlbertaAges 18–65 - NCT06764966RecruitingPhase 2
Statin and beta blocker study for liver disease
This trial tests if adding a statin to beta blocker treatment helps people with advanced liver disease (cirrhosis) who have had complications like fluid buildup, confusion, or bleeding. It is for patients who are already taking a non-selective beta blocker and will be followed for 12 months.
Charleston, West VirginiaAges 18 years+ - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06771323RecruitingPhase 2
Adding valbenazine to botox for neck muscle spasms
This study tests if adding a daily pill (valbenazine) to regular botox injections can better reduce neck muscle spasms. It helps people whose botox works but may not be enough.
Richmond, VirginiaAges 18–75 - NCT04281979Recruiting
Testing a substance’s effects in adult cigarette and vape users
This study tests how a specific substance affects people who currently smoke cigarettes or e-cigarettes. You may be able to join if you’re within a certain age range and recently had specific smoking and drinking patterns, and if you meet health/safety requirements for study procedures like MRI.
Portland, OregonAges 21–40 - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT06757140RecruitingPhase 1/Phase 2
Opioid and sedative-like drug interaction study
This study explores how opioids and sedative-like drugs interact in the body. It aims to understand their combined effects, which could help improve safety for people who use these drugs.
Lexington, KentuckyAges 18–55 - NCT06751784RecruitingPhase 2
Fampridine's effect on memory in mild to moderate depression
This study tests whether the drug fampridine can improve working memory (like short-term memory and focus) in people with mild to moderate depression. The trial is run by the University of Basel and involves multiple visits.
Basel, Canton of Basel-CityAges 18–55 - NCT06755307Recruiting
Probiotic cream for diaper rash in babies
This study tests whether a probiotic (beneficial bacteria) cream can help heal diaper rash in babies. It's for otherwise healthy infants under 2 who have diaper dermatitis.
MariborAges 1 month–2 years - NCT06756711Enrolling by invitation
Supplement combination for children with autism
This trial tests whether a combination of supplements can help children with autism spectrum disorder. It involves taking oral supplements daily for 6 months, along with blood tests and behavior assessments at the start, midpoint, and end.
BucharestAges 3–14 - NCT06752668RecruitingPhase 2
Testing ORX750 for narcolepsy and idiopathic hypersomnia
This trial tests an experimental drug called ORX750 for people with narcolepsy or idiopathic hypersomnia. You would need to stop your current sleepiness medicines to see if ORX750 helps reduce daytime sleepiness.
Auburn, AlabamaAges 18–65 - NCT06756269RecruitingPhase 2
HPV vaccine study for people aged 9 to 45
This trial tests a new 15-valent HPV vaccine to see if it is safe and creates a strong immune response. If you are between 9 and 45 years old and have not had an HPV vaccine before, you may be able to join.
Nanning, GuangxiAges 9–45 - NCT06756490RecruitingPhase 1
Study of HY-2003 for double chin reduction
This study tests a new medicine called HY-2003 to reduce extra fat under the chin (double chin). It is for adults who have moderate to severe submental fat and want to see if injections can help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06749808Enrolling by invitation
Nutritional supplement study for wellness and nutrient absorption
This trial tests whether a nutritional supplement can improve wellbeing and help your body absorb nutrients better. It might be a good fit if you are generally healthy and not already taking high-dose carotenoid supplements.
Provo, UtahAges 20–65 - NCT06448923RecruitingPhase 2
CBD for Pain and Opioid Reduction After Fracture
This trial tests if cannabidiol (CBD) can help reduce pain and the need for opioids after a broken arm or leg. If you recently broke a bone and are between 18 and 70, you might be able to join.
Montreal, QuebecAges 18–70 - NCT06745063RecruitingPhase 2
Study of a diabetes drug to reduce artery stiffness in veterans with obesity
This trial tests whether an SGLT2 inhibitor (a type of diabetes medication) can help reduce stiffness in the arteries of veterans who have obesity. If you are a veteran aged 30-60 with a BMI of 30-45 and have stiffer arteries than expected for your age, this study might be an option.
Columbia, MissouriAges 30–60
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.