Clinical trials
Placebo Effect clinical trials
Below are recruiting placebo effect clinical trials, each written for real people, not researchers. We’re tracking 758 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06827444Recruiting
How attention changes the placebo effect
This study looks at how your attention influences the placebo effect—the real benefits you can feel from a treatment that has no active ingredient. It may help us understand why some people respond better to placebos, which could improve future treatments.
Milan, MilanoAges 19–99 - NCT06533137Recruiting
How your mind can influence the placebo effect
This trial studies how your awareness and personal beliefs affect the placebo effect—a real improvement in symptoms from a treatment that has no active medicine. Researchers are looking at healthy people to understand how the mind and body interact, which could help improve future treatments.
MilanAges 18 years+ - NCT06980090Recruiting
How doctors' expectations affect their emotions
This study looks at how expecting to feel pain can change how doctors react emotionally. It uses brain scans (MRI) and mild electrical stimulation (tTIS) to understand these effects.
Hanover, New HampshireAges 18–55 - NCT07763574Enrolling by invitation
Strength training and omega-3 for muscle and brain health
This study tests whether combining strength training with omega-3 supplements improves muscle strength and thinking skills in healthy adults. You would either join an exercise group or a non-exercising control group.
GdanskAges 25–35 - NCT07666776Recruiting
Attention training for social anxiety: a controlled trial
This study tests whether a simple computer exercise that trains your attention away from threat can reduce social anxiety, compared to a placebo (neutral) version. It's for adults with social anxiety disorder and takes place at Tel Aviv University.
Tel AvivAges 18–65 - NCT07330466Recruiting
Does spinal cord stimulation work beyond a placebo?
This study investigates whether spinal cord stimulation (a device that sends mild electrical pulses to the spine to relieve pain) still works even when patients don't know if it's on. This helps separate the device's true effect from the expectation of feeling better.
Aarhus NAges 18 years+ - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT07247695Recruiting
Understanding how placebos affect different types of itch
This study looks at how a placebo might help reduce two kinds of itch: one caused by histamine (like an allergy) and another caused by other substances. You will receive different creams or patches to test how your body responds.
GistrupAges 18–60 - NCT05819476Recruiting
Testing how open-label placebos affect induced pain
This study tests whether people can feel less pain when they know they are receiving a “placebo” (a treatment with no active pain-relieving medicine). It’s done in healthy adults by triggering short-lasting pain in a controlled way to see how the placebo effect changes pain feelings.
BaselAges 18–65 - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+ - NCT06585033Recruiting
Spinal cord stimulation for pain after back surgery
This trial tests how much of the pain relief from spinal cord stimulation is due to the placebo effect. It is for people with ongoing leg pain after back surgery who have already tried other treatments without success.
ArnhemAges 18–70 - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT07363031Enrolling by invitationPhase 2
Valacyclovir for mouth sores during head and neck radiation
This trial tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores caused by radiation therapy for head and neck cancer.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06859723RecruitingPhase 1
Effects of high potency cannabis on daily users
This study tests how high potency cannabis affects mood, thinking, and pain sensitivity in people who smoke cannabis almost every day. It will help researchers understand both immediate and long-lasting effects.
Los Angeles, CaliforniaAges 21–55 - NCT06772753RecruitingPhase 1
Study of Psychedelic Effects in Healthy Adults
This study tests how certain psychoactive substances affect your mind and body. It is looking for healthy volunteers to take part in supervised sessions to explore the effects of these drugs.
Baltimore, MarylandAges 25–55 - NCT06720558Recruiting
Placebo probiotic effects on gut health in mild GI symptoms
This study tests whether a placebo probiotic can improve gut health and overall well-being in people with mild digestive issues like gas, bloating, or irregularity. If you have mild symptoms that don't stop your daily activities, this trial may help understand if believing you're taking a probiotic can make you feel better.
MilanAges 20–65 - NCT04166071Enrolling by invitationEarly Phase 1
Testing whether opioids plus support change learning behavior
This early study tests how opioid medicine, along with social support, affects how people learn or “unlearn” certain responses. If you’re healthy and meet safety requirements, it may help researchers understand how support could change the effects of pain-related medicines on behavior.
Los Angeles, CaliforniaAges 18–35 - NCT06677359Recruiting
Creatine and exercise for older adults
This study tests whether a creatine supplement, taken with or without a gentle exercise program, can help older adults stay stronger and more independent. It's designed for people aged 75 and older who can still walk.
Pamplona, NavarreAges 75 years+ - NCT07206407Recruiting
Study on how a test product affects your immune system
This trial tests whether a natural product can quickly change your immune system. It is looking for healthy adults who can keep a steady diet and lifestyle for the study period.
Klamath Falls, OregonAges 18–75 - NCT05599347RecruitingPhase 2
Azithromycin before anti-TNF treatment for Crohn’s disease
This Phase 2 trial tests whether taking azithromycin (an antibiotic) before starting infliximab or adalimumab can reduce the chance your body rejects the anti‑TNF medicine. It may help some people get better and keep responding to treatment.
Haifa, Haifa DistrictAges 18 years+ - NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06953869RecruitingPhase 3
Testing a sleep medicine for children with insomnia
This study tests if the drug tasimelteon helps children with insomnia sleep better compared to a placebo (a pill with no medicine). It is for children aged 2 to 17 who have been diagnosed with insomnia that is not caused by another medicine.
Dothan, AlabamaAges 2–17 - NCT06508710RecruitingPhase 3
Ketamine plus venlafaxine for severe depression
This trial tests whether adding ketamine to the antidepressant venlafaxine helps relieve severe depression faster than venlafaxine alone. If you are hospitalized for a serious depression and you meet safety criteria, you may be eligible.
Le Kremlin-Bicêtre, FranceAges 18–65 - NCT06750302RecruitingPhase 1/Phase 2
Penthrox vs placebo for sinus surgery pain
This trial tests if a pain reliever called Penthrox (methoxyflurane) works better than a placebo for pain during minor sinus procedures. If you are having a simple sinus surgery or coblation procedure, you may be able to join.
Vancouver, British ColumbiaAges 19 years+
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Placebo Effect trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for placebo effect?
- Yes. Clin2 currently lists 758 recruiting placebo effect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo effect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo effect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.