Testing setmelanotide for weight gain after brain injury
Treatments studied
Part of Brain & nervous system, Eyes & vision, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 4 or older
- You have obesity (BMI 30 or higher for adults, or at or above the 95th percentile for children)
- Weight gain started after a brain injury or condition that affects the hypothalamus, such as certain pituitary hormone deficiencies
- You must be willing to use effective birth control during the study and for 90 days after
- No major weight loss (more than 2%) in the last 3 months
- You cannot have had weight loss surgery in the last 2 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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