Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,941 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07771530RecruitingPhase 2
Medication or dog therapy for PTSD symptoms
This study tests whether a combination of two medications (reboxetine and Ritalin) is more effective than dog-assisted therapy for reducing PTSD symptoms. Participation involves either taking the medications or attending dog therapy sessions.
HaifaAges 18–70 - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07770464RecruitingPhase 2
Montelukast for acute bronchiolitis in infants
This study tests whether montelukast, a medicine that helps reduce airway inflammation, can improve symptoms of acute bronchiolitis (a common lung infection in babies) when given early. It may help babies breathe easier and recover faster.
Islamabad, FederalAges 4 weeks–2 years - NCT07771140RecruitingPhase 1
Study of an experimental injection for chronic hepatitis b
Doctors are testing a new injectable treatment for chronic hepatitis B. This first-in-human study checks the drug's safety and how well it works in people who are already on standard hepatitis B pills.
HefeiAges 18–65 - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in postmenopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce hot flashes and slow biological aging in postmenopausal women with obesity. It may help if you are experiencing bothersome hot flashes and are willing to follow a diet and exercise plan.
Jacksonville, FloridaAges 46–60 - NCT06666673RecruitingEarly Phase 1
Effects of a muscle relaxant on arm movement after stroke
This study looks at how the brain controls arm movements after a stroke. It tests whether a medication called tizanidine, which relaxes muscles, can improve arm function when combined with physical therapy.
Chicago, IllinoisAges 18–80 - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
Birmingham, AlabamaAges 18 years+ - NCT07668518RecruitingPhase 1/Phase 2
Study of KIT2014 for moderate to severe COPD
This trial tests a new medicine called KIT2014 in people with moderate to severe COPD. It aims to see if the drug is safe, tolerable, and helps improve breathing and COPD symptoms.
Charlestown, New South WalesAges 40–80 - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
Birmingham, AlabamaAges 18–74 - NCT05177510RecruitingPhase 2
Mifepristone to help start labor in some late pregnancies
This Phase 2 study tests whether mifepristone, taken by mouth, can help start labor when the cervix is not ready yet. It may help avoid needing other methods of induction, but it will only be offered if it’s safe for you and your baby.
LondonAges 18 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07065591RecruitingEarly Phase 1
Metformin, Exercise, and Diet for Knee Osteoarthritis
This trial tests whether a common diabetes drug (metformin) combined with exercise and a healthy diet can help people with knee osteoarthritis who are overweight.
Hong Kong, Sandy BayAges 40–80 - NCT05948943RecruitingPhase 2/Phase 3
Alpelisib for lymphatic malformations with a PIK3CA change
This trial tests alpelisib (a targeted medicine) for people who have lymphatic malformations (LyM) that cause symptoms and have a PIK3CA mutation. It may help shrink or control these lesions when other procedures are delayed until after the first 24 weeks.
Oakland, CaliforniaAges birth–100 years - NCT07621809RecruitingPhase 3
Ianalumab versus placebo for Sjögren's disease with high symptom burden
This study tests whether a new drug called ianalumab can reduce dry mouth and other symptoms in people with Sjögren's disease—a condition where the immune system attacks moisture-producing glands. Participants will receive either ianalumab or a placebo (inactive injection) over 52 weeks to see if the drug helps.
Peoria, ArizonaAges 18 years+ - NCT07088926RecruitingPhase 2
Study of a new medicine for bronchiectasis with chronic Pseudomonas infection
This study tests a new medicine (AZD0292) given through a vein for people with bronchiectasis and a chronic Pseudomonas lung infection. It aims to see if it can reduce flare-ups and improve lung health.
Orange, CaliforniaAges 12 years+ - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CharlestownAges 18–65 - NCT07220785RecruitingPhase 3
Testing mibavademab for generalized lipodystrophy in adults and children
This trial tests a new drug called mibavademab for people with generalized lipodystrophy, a condition where the body can't store fat properly, leading to problems like diabetes and high triglycerides. It aims to see if the drug safely improves these metabolic issues.
Ann Arbor, MichiganAges 2 years+ - NCT07298005RecruitingPhase 2
A study of Sonlicromanol for post-COVID patients
This trial tests a medicine called Sonlicromanol to see if it helps people with lingering symptoms after a mild case of COVID-19. It is for people who have post-exertional malaise (feeling very tired or worse after activity) and a moderate level of disability.
Amsterdam, North HollandAges 18–65 - NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74 - NCT06481306RecruitingPhase 1/Phase 2
Testing a new drug for sickle cell disease in healthy people and patients
This early-phase study tests a new drug (BMS-986470) for people with sickle cell disease who have frequent pain crises. The goal is to see if it can safely reduce crises. It includes a small group of healthy volunteers as well.
Birmingham, AlabamaAges 18 years+ - NCT06860984RecruitingPhase 3
Evaluating the Safety and Efficacy of Duloxetine in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis
This phase 3 trial tests duloxetine for preventing pancreatitis after ERCP in adults with normal baseline amylase/lipase and without certain comorbidities.
TantaAges 18–65 - NCT06736574RecruitingPhase 3
Study of omecamtiv mecarbil for chronic heart failure with very weak heart pump
This study tests an investigational medicine (omecamtiv mecarbil) for people with chronic heart failure and very low pumping strength. It looks at whether the drug can help prevent heart failure events or the need for stronger treatments.
Alexander City, AlabamaAges 18–85 - NCT06909565RecruitingPhase 4
Inclisiran to prevent heart and leg events after artery procedure
This study tests whether a twice-yearly injection called inclisiran can prevent heart attacks, strokes, or leg complications in people who recently had a procedure to open a blocked artery. You may be eligible if you had a heart or leg artery procedure within the last two weeks.
Alexander City, AlabamaAges 18 years+ - NCT04772079RecruitingPhase 3
Test drug safety and effectiveness for youth plaque psoriasis
This study checks whether deucravacitinib works well and is safe in children and teens with moderate to severe plaque psoriasis. It also looks at drug levels in the body to help understand how the treatment behaves over time.
Ciudad Autonoma de Buenos Aires, Buenos AiresAges 4–18
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,941 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.