Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05667090Recruiting
High-dose vitamin D3 to ease chronic pain in dialysis patients
This study tests whether taking a very high dose of vitamin D3 can reduce moderate to severe chronic pain in people on hemodialysis. It may help by improving vitamin D-related pathways that could affect pain, but you must also meet specific health and testing requirements.
TaipeiAges 20 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT05832580RecruitingPhase 3
Preventing calcium buildup in skin, eyes, and blood vessels
This Phase 3 study tests a medicine to help prevent abnormal calcium (called ectopic mineralization) from building up in people with pseudoxanthoma elasticum (PXE). It aims to slow or reduce new damage over time.
UtrechtAges 18–50 - NCT05851014RecruitingPhase 3
GB491 plus letrozole for HR+ HER2- advanced breast cancer
This Phase 3 study tests whether GB491 used together with letrozole works better for hormone receptor–positive and HER2-negative advanced breast cancer. You may be eligible if you have not had certain prior cancer treatments and your health tests are within safe limits.
Bengbu, AnhuiAges 18–75 - NCT05862337RecruitingPhase 3
New immune plus anti-cancer pills to prevent liver cancer returning
This Phase 3 trial studies anlotinib capsules plus penpulimab (an immune therapy) to help prevent hepatocellular carcinoma from coming back after it has been fully removed or fully destroyed. It may help high-risk patients lower the chance of recurrence and improve survival.
Bengbu, AnhuiAges 18–75 - NCT05899660Recruiting
Omega-3 for alcohol use disorder during withdrawal
This trial studies whether taking omega-3 supplements during a hospital alcohol-withdrawal program can improve recovery for people with alcohol use disorder. It may help by changing inflammation and how the body responds to stopping alcohol.
BrusselsAges 18–70 - NCT05275738Recruiting
Nicotinamide treatment for glaucoma progression
This trial studies whether nicotinamide (a form of vitamin B3/niacin) can slow or affect glaucoma progression. You may be eligible if you have newly diagnosed, untreated glaucoma or if you have treated glaucoma with measurable visual field changes.
StockholmAges 18 years+ - NCT05961644RecruitingPhase 2/Phase 3
Cladribine vs placebo for non-active progressive multiple sclerosis
This trial tests whether cladribine (vs an inactive placebo pill) can slow disability worsening in people with a non-active, progressive form of multiple sclerosis. It may help by reducing the immune activity that can drive ongoing nerve damage, even without recent relapses.
Warsaw, Masovian VoivodeshipAges 30–65 - NCT05962840RecruitingPhase 4
Rituximab plus telitacicept for ANCA vasculitis
This Phase 4 trial studies whether rituximab combined with telitacicept works better and is safe for people with severe active ANCA-associated vasculitis (including certain subtypes like GPA or MPA). If you meet specific blood test and disease activity criteria, you may be considered to help lower inflammation and prevent flare-ups.
BeijingAges 18–65 - NCT05623267RecruitingPhase 2/Phase 3
SugeMalimab after lung radiation and chemotherapy for limited-stage SCLC
This trial tests sugemalimab as “extra treatment” after standard chemoradiation for limited-stage small cell lung cancer. It aims to lower the chance of the cancer coming back by helping the immune system stay active after initial therapy.
Guangzhou, GuangdongAges 18 years+ - NCT04985344RecruitingPhase 3
Propranolol to treat PTSD symptoms in children using memory reactivation
This trial studies whether propranolol (a heart-related medicine) can help children with post-traumatic stress disorder (PTSD) after a special memory-activation session. The goal is to reduce PTSD symptoms compared with the comparison condition.
ToulouseAges 7–12 - NCT04558112RecruitingPhase 2
Levodopa for improving learning in PTSD
This study tests whether a medicine called levodopa, combined with brain imaging, can help improve learning and memory in people with PTSD. The goal is to see if it can help you better process trauma-related thoughts and improve your quality of life.
Austin, TexasAges 21–50 - NCT06050148RecruitingPhase 2/Phase 3
Fecal Transplant to Prevent Repeat Urinary Tract Infections
This trial tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) can help prevent repeat urinary tract infections in women who have frequent infections.
HelsinkiAges 18–90 - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79 - NCT06080776RecruitingPhase 3
SH-1028 vs placebo for early-stage EGFR-mutated lung cancer
This trial tests a pill called SH-1028 (an EGFR-targeted drug) versus a placebo to see if it helps prevent lung cancer from coming back after surgery in people with EGFR-mutated NSCLC. You may be eligible if you had complete removal of stage II-IIIB NSCLC and your tumor has a specific EGFR mutation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06088745RecruitingPhase 3
Shingles vaccine trial for adults 40+
This trial tests a new shingles vaccine to see how well it prevents shingles in adults aged 40 and older. It aims to help those who have not had shingles recently or been vaccinated against it before.
Zhenjiang, JiangsuAges 40 years+ - NCT05722782RecruitingPhase 2
Kidney stone pain treatment after ER discharge
This study compares an anti-inflammatory pain medicine (NSAID) given by mouth versus acetaminophen (paracetamol) or placebo after you leave the emergency room for a “renal colic” (kidney stone pain). It looks at whether the NSAID helps control pain better and whether it’s safe for people with uncomplicated kidney stone pain.
MonastirAges 18 years+ - NCT05908695RecruitingPhase 4
GV-971 treatment for mild to moderate Alzheimer’s disease
This Phase 4 trial tests whether a medicine called sodium oligomannate (GV-971) is safe and effective for people with mild to moderate Alzheimer’s disease. It may help slow or improve memory and thinking symptoms while carefully tracking side effects.
Huainan, AnhuiAges 50–85 - NCT05469165RecruitingPhase 2
Testing serotonin blockers after a first heart attack
This Phase 2 trial tests whether blocking serotonin receptors can help after a first heart attack that has caused a specific type of leaking mitral valve problem. It aims to see if the treatment improves heart function and heart-valve measurements while keeping patients safe.
QuébecAges 18–80 - NCT05851508RecruitingPhase 3
Steroid ear injections for vertigo in one-ear Ménière’s
This Phase 3 study compares injections of steroid medicine into the ear versus a dummy (placebo) injection to see if it reduces vertigo attacks in people with Ménière’s disease. It may help by improving balance symptoms and reducing how often attacks happen.
Leiden, South HollandAges 18–100 - NCT05930613RecruitingPhase 3
Certolizumab for repeated embryo transfer pregnancy failure
This Phase 3 study tests certolizumab to help people with repeated embryo transfer failures achieve a clinical pregnancy. It may be an option if your infertility has no known cause and you meet the other study checks.
ParisAges 18–40 - NCT06163833RecruitingPhase 2
Stem cell treatment for severe traumatic brain injury
This study tests whether a treatment made from donor stem cells (called mesenchymal stromal cells) can help people recover from a severe traumatic brain injury. The cells are given through a vein within 48 hours of the injury.
Monza, MBAges 18–70 - NCT06152497Recruiting
Histamine and muscle growth after strength training
This study looks at how histamine affects muscle building after resistance exercise. It may help us understand why some people build muscle better than others after strength training.
Ghent, Oost-VlaanderenAges 18–45
Hear when a new Placebo - Control trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.