Clinical trials
Polygenic Risk Score clinical trials
Below are recruiting polygenic risk score clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06398639Recruiting
Using genetic risk and MRI to find dangerous prostate cancer
This study uses a genetic risk score and a special MRI scan to find prostate cancers that are more likely to be dangerous. It aims to see if combining these tests can better identify which men need a biopsy.
Washington D.C., District of ColumbiaAges 40–69 - NCT06888466Recruiting
Personalized heart health risk check
This trial looks at how learning about your genetic risk for heart disease might help prevent it. You will get a personalized report and guidance.
Roma, ItaliaAges 40 years+ - NCT06935344Recruiting
Can genes predict ovarian cancer risk?
This study looks at whether a score based on your genes can predict the risk of epithelial ovarian cancer. It compares women newly diagnosed with this cancer to women who have never had it.
Roma, ItaliaAges 18 years+ - NCT06917794Enrolling by invitation
Genetic risk study for colon cancer patients
This study looks at how your genetic background and ancestry affect your risk for colon cancer. If you have been diagnosed with colon cancer and have a tumor sample available, you may be able to help researchers develop better risk scores.
Fortaleza, CearáAges 18 years+ - NCT06542432Enrolling by invitation
Genetic risk test for heart disease prevention
This trial uses a polygenic risk score to see if knowing your genetic risk for coronary artery disease can help prevent a first heart attack. If you have an intermediate 10-year risk and no prior heart events, you may be eligible.
Rochester, MinnesotaAges 40–70 - NCT06922708Recruiting
Using genetic risk scores to improve breast cancer prevention
This study is testing a new way to use your genetic information (along with your family history) to better understand your personal risk for breast cancer. The goal is to see if giving this risk report to women with higher genetic risk can help them and their doctors make more informed decisions about screening and prevention.
RomaAges 18–79 - NCT07738003Recruiting
Perinatal Autism Genetics and Epigenetics Study
This study looks at genetics and other factors that may be linked to autism. Pregnant women in their first or second trimester are invited to join, and their babies will be followed to see how they develop.
Iowa City, IowaAges birth–50 years - NCT06586203Recruiting
Genomic test to guide diabetes heart and kidney care
This study is testing whether a special blood test (genomic predictor) can help doctors better manage heart and kidney risks in people with type 2 diabetes. You may benefit from learning your personal risk score and getting more tailored care.
Montreal, QuebecAges 18 years+ - NCT06911294Recruiting
Personalized Heart Prevention Study
This study tests new, personalized ways to prevent heart disease in people with metabolic syndrome. It aims to see if custom approaches can lower your risk of heart attacks and strokes.
Rome, ItalyAges 40–69 - NCT06962488Recruiting
Personalized blood pressure care using genetic risk
This study uses your genetic information (a polygenic risk score) to guide personalized blood pressure management. It aims to help people with high blood pressure and overall poor heart health improve their levels through tailored advice.
Birmingham, AlabamaAges 18–55 - NCT07087431Recruiting
Genetic risk score for heart disease and health habits
This study looks at whether sharing a genetic risk score for heart disease can help people make heart-healthy changes. If you're not on cholesterol medication, you may be able to join.
Boston, MassachusettsAges 30–75 - NCT07641582Recruiting
Gene Testing to Predict Heart Rhythm Problems
This study uses a genetic test to identify who might develop atrial fibrillation (an irregular heartbeat) in the future. Researchers believe certain genetic patterns combined with health factors can help predict this condition early, which could lead to better prevention.
IncheonAges 20–79 - NCT07091162Recruiting
Genetic and CT screening for heart risk in diabetes
This trial uses your genetic risk score and a CT scan of your heart to see if changing how doctors manage your diabetes can lower your risk of heart problems. It is for adults with type 2 diabetes who haven't had heart disease symptoms.
Melbourne, VictoriaAges 40 years+
Hear when a new Polygenic Risk Score trial opens
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Common questions
- Are there clinical trials for polygenic risk score?
- Yes. Clin2 currently lists 13 recruiting polygenic risk score studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a polygenic risk score trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a polygenic risk score trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.