Clinical trials
Postpartum Depression clinical trials
Below are recruiting postpartum depression clinical trials, each written for real people, not researchers. We’re tracking 71 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07398469Recruiting
Long-term study of zuranolone for postpartum depression symptoms
This study checks how people with postpartum depression feel over time after starting zuranolone. It uses simple questionnaires to track changes in symptoms.
Cambridge, MassachusettsAges 18 years+ - NCT06767566RecruitingPhase 1
Ketamine for depression and pain after cesarean delivery
This study tests whether ketamine, a medicine given during cesarean delivery, can help prevent or reduce postpartum depression and pain. It aims to find the best dose for new mothers.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06545760Recruiting
Skin-to-skin care and mothers' mood after preterm birth
This study looks at whether giving kangaroo mother care (skin-to-skin contact) to a small or premature baby affects the mother's mood after childbirth. It may help understand how to support mothers' emotional well-being during their baby's hospital stay.
LusakaAges 1 day–89 years - NCT06628986Recruiting
Mindfulness and NLP for postpartum mood and breastfeeding
This study tests whether combining mindfulness (MBSR) and a gentle brain-training method (NLP) can help new mothers feel better after childbirth and improve their breastfeeding experience. It may be a good fit if you are a first-time mom who had a C-section and is breastfeeding.
Sanliurfa, Eyalet/YerleşkeAges 19–35 - NCT05097586Recruiting
At-home brain stimulation trial for depression during pregnancy
This trial tests whether doing at-home, noninvasive brain stimulation (tDCS) can reduce depression symptoms during pregnancy. It may help people who are in a depressive episode but prefer not to take antidepressant medication right now.
Toronto, OntarioAges 18 years+ - NCT05800509Recruiting
Program for gestational diabetes and low mood in pregnancy
This study offers an intervention program to help people who are diagnosed with gestational diabetes and may also experience depression during pregnancy. It may help improve health during pregnancy and support mood and well-being with smartphone-based participation.
TaipeiAges 20 years+ - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT05830266Recruiting
Mindfulness program to help mother–baby bonding in pregnancy and after
This study tests a mindfulness-based program to improve mother–baby bonding by supporting mood, anxiety, and stress during and after pregnancy. It may help if you’re currently having higher-than-average depression, anxiety, or stress symptoms.
Tilburg, North BrabantAges 18 years+ - NCT07607613Recruiting
Support for LGBTQ+ Parents with Depression Risk
This study offers group support sessions for LGBTQ+ parents who are pregnant or recently had a baby and are experiencing mild depression or worry about postpartum depression. The goal is to help prevent depression from getting worse and improve emotional well-being during this important life transition.
Chicago, IllinoisAges 18 years+ - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+ - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT05676918Recruiting
Postpartum well-being study for mothers in the past year
This study looks at mothers’ well-being after having a baby, to understand what affects mental and emotional health after childbirth. It may help improve support for mothers during the postnatal period.
Madrid, Pozuelo de AlarcónAges 18 years+ - NCT06277661Recruiting
Mom and Infant Outcomes Study
This study tests a program to support pregnant people who have had high blood pressure, diabetes, or depression/anxiety. It aims to improve outcomes for both mothers and babies.
Columbus, OhioAges Any age - NCT04685148RecruitingPhase 1/Phase 2
Study of mental health treatment during pregnancy
This trial studies a treatment aimed at improving maternal mental health during pregnancy. It focuses on people who have had depression around pregnancy before, and checks whether the approach is safe and helpful for them.
CopenhagenAges 18–45 - NCT07523932Recruiting
Digital check-ins after cesarean delivery with a midwife
This study tests whether receiving digital (phone or app) follow-up care from a midwife after cesarean delivery helps with your recovery and your baby's health. You'll be compared to standard care to see if this new approach works well.
GiresunAges 18–45 - NCT07485036Recruiting
Study on mood and alcohol use in new mothers
This study looks at how new mothers feel emotionally, including mood, alcohol use, and symptoms of depression. By participating, you can help researchers understand the challenges mothers face in the first year after childbirth.
Chicago, IllinoisAges 18 years+ - NCT06702722Recruiting
Therapy and HIV support for moms in Malawi
This study tests if combining problem-solving therapy with HIV care support can improve mental health and HIV outcomes for pregnant women living with HIV in Malawi who have elevated depressive symptoms.
LilongweAges 18 years+ - NCT05763537Recruiting
Study exploring how doulas support pregnancy mood changes
This study looks at how having a doula affects support and wellbeing for people experiencing pregnancy-related mood and anxiety changes. It may help you and others learn what kind of doula support is most helpful during pregnancy.
Missoula, MontanaAges 18 years+ - NCT05400382Recruiting
Mindfulness for depression and pain after cesarean delivery
This study tests whether a mindfulness program can help new mothers manage pain and depression after a planned cesarean delivery. You might be eligible if you are a woman of color or non-Hispanic White with a history of depression and are scheduled for a planned C-section.
Champaign, IllinoisAges 18–45 - NCT07354334Enrolling by invitation
Listening to a Quranic surah after cesarean birth
This study tests if listening to Surah Al-Inshirah after a cesarean helps new mothers feel better. It looks at things like pain, anxiety, and recovery.
Konya, SelçukluAges 18–45 - NCT07272252Recruiting
Nursing support to reduce anxiety after planned C-section
This study tests a special kind of nursing care (narrative nursing) to see if it helps mothers feel less anxious and more confident about breastfeeding after a planned, full-term cesarean section. If you are having a scheduled C-section with a healthy pregnancy and baby, you may be able to join.
Nanchong, SichuanAges 18–50 - NCT07083492Recruiting
Detecting iron deficiency in pregnancy and after birth
This study uses a non-invasive test to check for iron deficiency in women during pregnancy and up to 3 months after giving birth. It aims to make detection easier and more comfortable for you.
Würzburg, BavariaAges 18 years+ - NCT07799805Recruiting
Doula support for pregnant women in North Central Florida
This study looks at whether having a doula—a trained support person—during pregnancy can help reduce stress and improve health outcomes for mothers. It is designed for women who are eligible for Medicaid and live in North Central Florida.
Gainesville, FloridaAges 15–49 - NCT05961306Recruiting
Testing a stepped screening plan during pregnancy and after birth
This study checks how well a step-by-step screening approach and its tools work for identifying issues during pregnancy (weeks 20–24) or in early postpartum (6–10 weeks after delivery). It may help doctors use more accurate screening to decide who needs further care.
Ghent, Oost-VlaanderenAges 18 years+
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Common questions
- Are there clinical trials for postpartum depression?
- Yes. Clin2 currently lists 71 recruiting postpartum depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postpartum depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postpartum depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.