Clinical trials · Raleigh–Durham, NC
Pregnancy clinical trials in Raleigh–Durham
We’re tracking 33 recruiting pregnancy studies with a site in or near Raleigh–Durham — including Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT06259669Recruiting
Studying eczema cream safety during pregnancy
This study compares the health of mothers and their babies in two groups: women with eczema who used ruxolitinib cream during pregnancy and those who did not. It aims to see if the cream is safe for both mother and child.
Morrisville, North CarolinaAges 15–50 - NCT06627335Recruiting
Eczema creams and pregnancy outcomes study
This study looks at women who used a topical eczema cream called ruxolitinib (Opzelura) or steroid creams during pregnancy. The goal is to compare pregnancy outcomes and baby health up to one year after birth.
Morrisville, North CarolinaAges 14 years+ - NCT06628687Recruiting
Study checking omaveloxolone health effects during pregnancy and breastfeeding
This study follows people with Friedreich's ataxia who took omaveloxolone during pregnancy or while breastfeeding, to check how the drug affected their health and their baby's health. It helps doctors understand the safety of this treatment for mothers and babies.
Morrisville, North CarolinaAges 16 years+ - NCT05536011Recruiting
Pregnancy registry for women taking WAKIX (pitolisant)
This registry collects information about pregnancy outcomes in women who took WAKIX (pitolisant) or a similar comparison medicine during pregnancy. It helps doctors understand the safety and effects of these medicines in pregnancy.
Morrisville, North CarolinaAges Any age - NCT05103254Recruiting
Pregnancy monitoring for bempedoic acid medicine use
This study follows people during and after pregnancy who took bempedoic acid (either alone or with ezetimibe). It collects safety information to better understand how this medicine may affect pregnancy outcomes.
Morrisville, North CarolinaAges 18 years+ - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT06413420Recruiting
Study of Solriamfetol Use During Pregnancy
This registry study tracks the safety of Sunosi (solriamfetol) and other wakefulness medications taken during pregnancy. It aims to gather information to help doctors and pregnant women make informed treatment decisions.
Morrisville, North CarolinaAges Any age - NCT07049653Recruiting
Anifrolumab pregnancy safety study
This study looks at pregnancy outcomes in women with lupus (SLE) who were or were not treated with the drug anifrolumab. It helps understand if anifrolumab is safe to use during pregnancy.
Cary, North CarolinaAges 18–130 - NCT04364503Enrolling by invitation
Study that analyzes de-identified patient samples and records
This trial checks how well patient samples and health records can be analyzed when names are removed (“de-identified”) and privacy rules are followed. You might be included if you agree in writing and your sample data can be used for this research and/or your doctor requests it.
Research Triangle Park, North CarolinaAges Any age - NCT07117708Recruiting
Timing of cesarean consent discussions during labor
This study looks at when to talk with patients about the possibility of an unplanned cesarean section before or during labor. It may help make the consent process less stressful for people who are planning to have their labor started.
Durham, North CarolinaAges 18 years+ - NCT05658497Recruiting
MS pregnancy registry for Vumerity (diroximel fumarate) exposure
This study collects information about pregnancies in people with multiple sclerosis (MS) who were exposed to Vumerity (diroximel fumarate) or who were not on MS medicines during pregnancy. It helps researchers understand pregnancy outcomes and safety in these situations.
Durham, North CarolinaAges Any age - NCT06498128Recruiting
Pregnancy safety registry for insomnia drug QUVIVIQ
This registry follows pregnant women with insomnia who used or did not use the sleep medication QUVIVIQ. It aims to track pregnancy and baby outcomes to understand safety.
Durham, North CarolinaAges 15–50 - NCT03276923Recruiting
Pregnancy registry for women with autoimmune disease
This study is a pregnancy and health registry for women with autoimmune (immune system) conditions who are trying to become pregnant or are already pregnant. It helps researchers better understand pregnancy outcomes and health needs in autoimmune disease.
Durham, North CarolinaAges Any age - NCT00567073Recruiting
Register pregnant people with Pompe disease for pregnancy data
This study keeps a special record of pregnancies in people with Pompe disease to learn more about pregnancy outcomes and newborn information. It does not test a drug by itself—it collects health information to improve future care.
Durham, North CarolinaAges Any age - NCT00358943Recruiting
Gaucher disease registry and pregnancy tracking study
This study creates a large, long-term record of people with Gaucher disease and details about pregnancy outcomes. It helps researchers better understand Gaucher over a person’s life and during pregnancy.
Durham, North CarolinaAges Any age - NCT00196742Recruiting
Fabry disease registry and pregnancy follow-up
This study collects health information from people with Fabry disease and specifically from pregnant people with Fabry disease. It helps researchers better understand the condition and how pregnancy affects health, using information you already experience in routine care.
Durham, North CarolinaAges Any age - NCT05158894Recruiting
Pregnancy safety registry for migraine medicines Ubrelvy and Qulipta
This is an observational study (no treatment is assigned) that tracks side effects and pregnancy outcomes in people taking Ubrelvy or Qulipta for migraine during pregnancy. It may help doctors better understand how these medicines affect mothers and babies.
Durham, North CarolinaAges 18 years+ - NCT05756244Recruiting
Managing blood thinners during pregnancy to prevent clot problems
This study looks at the best way to manage blood thinners (like injections of LMWH) during pregnancy for people who need them because of a past or current blood clot risk. It may help by improving how safely and effectively anticoagulation is handled to reduce clot complications.
Durham, North CarolinaAges 18–60 - NCT06150781Recruiting
Aimovig pregnancy safety study for migraine
This study tracks the health of pregnant women with migraine who take Aimovig. It helps doctors understand if the medicine is safe to use during pregnancy.
Durham, North CarolinaAges 18–99 - NCT06411158Recruiting
Pelvic floor training for urine leakage after first baby
This study tests whether a pelvic floor training program delivered through a smartphone app can help first-time moms who leak urine after childbirth. The program is designed for women who had a vaginal delivery with certain risk factors for ongoing pelvic floor issues.
Durham, North CarolinaAges 18 years+ - NCT06866405RecruitingPhase 3
RSV vaccine boost in a new pregnancy
This study tests whether a second dose of the RSV vaccine during a new pregnancy protects you and your baby from RSV. If you received the RSVpreF or Abrysvo vaccine in a past pregnancy, you may be able to join.
Durham, North CarolinaAges birth+ - NCT06940869Enrolling by invitation
Reproductive health registry for rheumatic conditions
This study creates a registry to better understand pregnancy outcomes in people with autoimmune or rheumatic conditions. If you are aged 12 to 55, can become pregnant (or are currently pregnant or planning a pregnancy), and receive care at Duke Health, you may be eligible to join.
Durham, North CarolinaAges 12–55 - NCT05484804Recruiting
Improving Black maternal care by undoing inequities
This study tests a care improvement plan in prenatal clinics to reduce inequities in how care is delivered to Black pregnant people. It may help clinics change practices and use tools that better spot problems early and improve support like doula care.
Chapel Hill, North CarolinaAges 12–99 - NCT01073475Recruiting
Pregnancy and birth registry for community health research
This trial is a long-term registry that collects pregnancy and birth information in a community to help researchers study maternal and newborn health. It may help you and others by improving understanding of care and outcomes across many pregnancies.
Chapel Hill, North CarolinaAges Any age
Hear when a new Pregnancy trial opens near Raleigh–Durham, NC
We’ll email you when one opens near Raleigh–Durham, NC — at most once a week, no account needed, unsubscribe anytime.
Pregnancy trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting pregnancy studies listed above.
- Duke University Medical Center · 7 studies
- Evidera, a PPD business unit · 5 studies
- Duke University · 2 studies
- IQVIA US Office · 2 studies
- IQVIA Virtual Site · 2 studies
- Syneos Health · 2 studies
- University of North Carolina at Chapel Hill · 2 studies
- Labcorp
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pregnancy studies in North Carolina.
Common questions
- Are there pregnancy clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 33 recruiting pregnancy studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.