Clinical trials · North Carolina
Pregnancy clinical trials in North Carolina
We’re tracking 50 recruiting pregnancy studies with a site in North Carolina — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05739123Recruiting
Pregnancy safety registry for relugolix-containing medicines
This is an observational study that collects real-world information about pregnancy outcomes when relugolix-containing therapy is taken during pregnancy. It aims to better understand safety for both the parent during pregnancy and the child after birth.
Wilmington, North CarolinaAges birth+ - NCT06258902Recruiting
Odevixibat pregnancy and breastfeeding safety study
This study tracks the safety of odevixibat (a liver medicine) in women who took it during pregnancy or while breastfeeding. It helps patients and doctors understand if the medicine poses any risks.
Wilmington, North CarolinaAges Any age - NCT07556913Recruiting
Safety study of elafibranor medicine during pregnancy
This study tracks the safety of a medicine called elafibranor when taken before or during pregnancy. Researchers want to understand how the medicine affects pregnant people and their babies to help keep both safe.
Wilmington, North CarolinaAges Any age - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT07661433Recruiting
Testing an AI tool to estimate baby weight before birth
This trial tests whether an artificial intelligence (AI) tool can more accurately estimate a baby's weight using ultrasound, compared to standard methods. If you're about to give birth, this study may help improve how doctors predict your baby's size.
Chapel Hill, North CarolinaAges 18 years+ - NCT04421768Recruiting
Training for cervical exams in labor and delivery care
This trial studies whether a structured training program helps healthcare staff perform cervical exams more effectively during labor. It may improve how labor and delivery care is delivered at the hospital.
Winston-Salem, North CarolinaAges Any age - NCT04805502Recruiting
Pregnancy exercise program to help prevent childhood obesity
This trial studies whether a structured exercise program during pregnancy can help lower the risk of childhood obesity. If you qualify, you may be asked to exercise during early pregnancy and share information with the research team.
Greenville, North CarolinaAges 18–45 - NCT05103254Recruiting
Pregnancy monitoring for bempedoic acid medicine use
This study follows people during and after pregnancy who took bempedoic acid (either alone or with ezetimibe). It collects safety information to better understand how this medicine may affect pregnancy outcomes.
Morrisville, North CarolinaAges 18 years+ - NCT05536011Recruiting
Pregnancy registry for women taking WAKIX (pitolisant)
This registry collects information about pregnancy outcomes in women who took WAKIX (pitolisant) or a similar comparison medicine during pregnancy. It helps doctors understand the safety and effects of these medicines in pregnancy.
Morrisville, North CarolinaAges Any age - NCT05939700Recruiting
Watching infants after mavacamten use in pregnancy
This study follows people who took mavacamten during pregnancy or breastfeeding to better understand infant outcomes. It may help doctors and families know what to expect and improve safety guidance.
Wilmington, North CarolinaAges 15 years+ - NCT06259669Recruiting
Studying eczema cream safety during pregnancy
This study compares the health of mothers and their babies in two groups: women with eczema who used ruxolitinib cream during pregnancy and those who did not. It aims to see if the cream is safe for both mother and child.
Morrisville, North CarolinaAges 15–50 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Chapel Hill, North CarolinaAges 14–35 - NCT06627335Recruiting
Eczema creams and pregnancy outcomes study
This study looks at women who used a topical eczema cream called ruxolitinib (Opzelura) or steroid creams during pregnancy. The goal is to compare pregnancy outcomes and baby health up to one year after birth.
Morrisville, North CarolinaAges 14 years+ - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
Chapel Hill, North CarolinaAges 18–50 - NCT06910553Recruiting
IBD Pregnancy Registry for mothers
This study is a registry that collects information from pregnant people with inflammatory bowel disease. By joining, you help researchers understand how IBD and treatments affect pregnancy and baby health.
Wilmington, North CarolinaAges 18–50 - NCT06940869Enrolling by invitation
Reproductive health registry for rheumatic conditions
This study creates a registry to better understand pregnancy outcomes in people with autoimmune or rheumatic conditions. If you are aged 12 to 55, can become pregnant (or are currently pregnant or planning a pregnancy), and receive care at Duke Health, you may be eligible to join.
Durham, North CarolinaAges 12–55 - NCT06866405RecruitingPhase 3
RSV vaccine boost in a new pregnancy
This study tests whether a second dose of the RSV vaccine during a new pregnancy protects you and your baby from RSV. If you received the RSVpreF or Abrysvo vaccine in a past pregnancy, you may be able to join.
Durham, North CarolinaAges birth+ - NCT05658497Recruiting
MS pregnancy registry for Vumerity (diroximel fumarate) exposure
This study collects information about pregnancies in people with multiple sclerosis (MS) who were exposed to Vumerity (diroximel fumarate) or who were not on MS medicines during pregnancy. It helps researchers understand pregnancy outcomes and safety in these situations.
Durham, North CarolinaAges Any age - NCT06942598Recruiting
Food support program for pregnant women facing food insecurity
This trial tests a program to help pregnant women who have trouble getting enough food. It provides special meals and support to improve food security and health for both mother and baby.
Winston-Salem, North CarolinaAges 18 years+ - NCT05484804Recruiting
Improving Black maternal care by undoing inequities
This study tests a care improvement plan in prenatal clinics to reduce inequities in how care is delivered to Black pregnant people. It may help clinics change practices and use tools that better spot problems early and improve support like doula care.
Chapel Hill, North CarolinaAges 12–99 - NCT01134770Enrolling by invitation
Study of how pregnancy drug exposure affects newborn response
This study looks at how certain exposures during pregnancy can affect a baby’s early physical and brain responses. It may help researchers understand what differences to expect and how early changes can be measured.
Chapel Hill, North CarolinaAges 18–45 - NCT07117708Recruiting
Timing of cesarean consent discussions during labor
This study looks at when to talk with patients about the possibility of an unplanned cesarean section before or during labor. It may help make the consent process less stressful for people who are planning to have their labor started.
Durham, North CarolinaAges 18 years+ - NCT05912517RecruitingPhase 3
Nipocalimab for high-risk pregnancy blood disease
This Phase 3 trial tests nipocalimab (an antibody medicine) to help prevent severe blood breakdown in a baby when a parent has certain blood antibodies. It enrolls people who previously had severe hemolytic disease in a past pregnancy and who are currently early in pregnancy with the same risk antibodies.
Chapel Hill, North CarolinaAges 18–45 - NCT06598098Recruiting
Healthy Weight and Exercise in Early Pregnancy Study
This study looks at how exercise during early pregnancy (first 16 weeks) may help women with a healthy body weight. Researchers want to see if staying active can support a healthy pregnancy and baby.
Greenville, North CarolinaAges 18–40
Pregnancy trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting pregnancy studies listed above.
- University of North Carolina at Chapel Hill · 5 studies
- PPD · 4 studies
- Evidera, a PPD business unit · 3 studies
- Duke University Medical Center · 2 studies
- East Carolina University · 2 studies
- Syneos Health · 2 studies
- Virtual Research Coordination Center · 2 studies
- Wake Forest University Health Sciences · 2 studies
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pregnancy trials in other states
Common questions
- Are there pregnancy clinical trials in North Carolina?
- Yes. We're currently tracking 50 recruiting pregnancy studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.