Clinical trials · North Carolina
Pregnancy clinical trials in North Carolina
We’re tracking 51 recruiting pregnancy studies with a site in North Carolina — including Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05739123Recruiting
Pregnancy safety registry for relugolix-containing medicines
This is an observational study that collects real-world information about pregnancy outcomes when relugolix-containing therapy is taken during pregnancy. It aims to better understand safety for both the parent during pregnancy and the child after birth.
Wilmington, North CarolinaAges birth+ - NCT07556913Recruiting
Safety study of elafibranor medicine during pregnancy
This study tracks the safety of a medicine called elafibranor when taken before or during pregnancy. Researchers want to understand how the medicine affects pregnant people and their babies to help keep both safe.
Wilmington, North CarolinaAges Any age - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT06258902Recruiting
Odevixibat pregnancy and breastfeeding safety study
This study tracks the safety of odevixibat (a liver medicine) in women who took it during pregnancy or while breastfeeding. It helps patients and doctors understand if the medicine poses any risks.
Wilmington, North CarolinaAges Any age - NCT05103254Recruiting
Pregnancy monitoring for bempedoic acid medicine use
This study follows people during and after pregnancy who took bempedoic acid (either alone or with ezetimibe). It collects safety information to better understand how this medicine may affect pregnancy outcomes.
Morrisville, North CarolinaAges 18 years+ - NCT07661433Recruiting
Testing an AI tool to estimate baby weight before birth
This trial tests whether an artificial intelligence (AI) tool can more accurately estimate a baby's weight using ultrasound, compared to standard methods. If you're about to give birth, this study may help improve how doctors predict your baby's size.
Chapel Hill, North CarolinaAges 18 years+ - NCT06910553Recruiting
IBD Pregnancy Registry for mothers
This study is a registry that collects information from pregnant people with inflammatory bowel disease. By joining, you help researchers understand how IBD and treatments affect pregnancy and baby health.
Wilmington, North CarolinaAges 18–50 - NCT06940869Enrolling by invitation
Reproductive health registry for rheumatic conditions
This study creates a registry to better understand pregnancy outcomes in people with autoimmune or rheumatic conditions. If you are aged 12 to 55, can become pregnant (or are currently pregnant or planning a pregnancy), and receive care at Duke Health, you may be eligible to join.
Durham, North CarolinaAges 12–55 - NCT06628453Recruiting
Continuous glucose monitor for type 2 diabetes in pregnancy
This study tests whether using a CGM (a small sensor that tracks blood sugar) can help manage type 2 diabetes during pregnancy better than standard care. It is for women who have type 2 diabetes and are pregnant with one baby.
Chapel Hill, North CarolinaAges 18–50 - NCT06627335Recruiting
Eczema creams and pregnancy outcomes study
This study looks at women who used a topical eczema cream called ruxolitinib (Opzelura) or steroid creams during pregnancy. The goal is to compare pregnancy outcomes and baby health up to one year after birth.
Morrisville, North CarolinaAges 14 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Chapel Hill, North CarolinaAges 14–35 - NCT06259669Recruiting
Studying eczema cream safety during pregnancy
This study compares the health of mothers and their babies in two groups: women with eczema who used ruxolitinib cream during pregnancy and those who did not. It aims to see if the cream is safe for both mother and child.
Morrisville, North CarolinaAges 15–50 - NCT05939700Recruiting
Watching infants after mavacamten use in pregnancy
This study follows people who took mavacamten during pregnancy or breastfeeding to better understand infant outcomes. It may help doctors and families know what to expect and improve safety guidance.
Wilmington, North CarolinaAges 15 years+ - NCT05536011Recruiting
Pregnancy registry for women taking WAKIX (pitolisant)
This registry collects information about pregnancy outcomes in women who took WAKIX (pitolisant) or a similar comparison medicine during pregnancy. It helps doctors understand the safety and effects of these medicines in pregnancy.
Morrisville, North CarolinaAges Any age - NCT04805502Recruiting
Pregnancy exercise program to help prevent childhood obesity
This trial studies whether a structured exercise program during pregnancy can help lower the risk of childhood obesity. If you qualify, you may be asked to exercise during early pregnancy and share information with the research team.
Greenville, North CarolinaAges 18–45 - NCT04421768Recruiting
Training for cervical exams in labor and delivery care
This trial studies whether a structured training program helps healthcare staff perform cervical exams more effectively during labor. It may improve how labor and delivery care is delivered at the hospital.
Winston-Salem, North CarolinaAges Any age - NCT06521944Recruiting
RSV vaccine safety registry for pregnant people
This registry follows pregnant people who received an RSV vaccine during a specific window (32 to 36 weeks) to monitor safety. If you got the shot in that time, your information helps researchers understand how well the vaccine works in pregnancy.
Wilmington, North CarolinaAges 18–50 - NCT07557303Recruiting
Understanding Prenatal Screening Decisions During Pregnancy
This study helps pregnant people make informed choices about genetic screening tests by providing clear, timely information. Researchers want to learn the best way to explain screening options so you can decide what's right for you and your family.
Chapel Hill, North CarolinaAges 18 years+ - NCT07525193Recruiting
Prenatal choline supplements and infant health outcomes
This study tests whether taking choline supplements during pregnancy helps babies develop better. Choline is a nutrient found in foods like eggs and chicken that supports brain development.
Greenville, North CarolinaAges 18–40 - NCT07356518Recruiting
Telehealth and Remote Blood Pressure for Pregnancy
This study tests if using telehealth and remote blood pressure monitoring can help manage high blood pressure during pregnancy. It may be a good fit if you already had high blood pressure before pregnancy and want to monitor it from home.
Winston-Salem, North CarolinaAges 18–45 - NCT07271758Enrolling by invitation
Omega-3 blood screening in early pregnancy
This study tests if checking DHA (a key omega-3 fatty acid) levels early in pregnancy helps you and your baby. You may get results and guidance to improve your diet.
Winston-Salem, North CarolinaAges Any age - NCT00404989Recruiting
Pregnancy drug safety registry for people with HIV treatment
This trial is a pregnancy registry that collects information about birth outcomes when certain HIV medicines are taken during pregnancy. It helps detect any major birth defects so future pregnancies can be safer.
Wilmington, North CarolinaAges 12–60 - NCT07117708Recruiting
Timing of cesarean consent discussions during labor
This study looks at when to talk with patients about the possibility of an unplanned cesarean section before or during labor. It may help make the consent process less stressful for people who are planning to have their labor started.
Durham, North CarolinaAges 18 years+ - NCT07049653Recruiting
Anifrolumab pregnancy safety study
This study looks at pregnancy outcomes in women with lupus (SLE) who were or were not treated with the drug anifrolumab. It helps understand if anifrolumab is safe to use during pregnancy.
Cary, North CarolinaAges 18–130
Pregnancy trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting pregnancy studies listed above.
- PPD · 3 studies
- Wake Forest University Health Sciences · 3 studies
- East Carolina University · 2 studies
- Syneos Health (remote site) · 2 studies
- University of North Carolina · 2 studies
- University of North Carolina Chapel Hill · 2 studies
- Virtual Research Coordination Center · 2 studies
- Duke Medical Center
What taking part in a pregnancy study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pregnancy trials in other states
Common questions
- Are there pregnancy clinical trials in North Carolina?
- Yes. We're currently tracking 51 recruiting pregnancy studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pregnancy study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pregnancy trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pregnancy studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.