Clinical trials
Premature Birth clinical trials
Below are recruiting premature birth clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07413900Recruiting
Brain injury study for babies and toddlers
This study looks at biomarkers (biological signs) in infants who had a brain injury around birth or were born very early, and compares them with healthy babies. The goal is to learn more about brain injuries and recovery.
Madison, WisconsinAges 3 months–2 years - NCT07306793Recruiting
Mouth care and meal timing for preterm infants ready to eat
This study tests whether a gentle mouth care routine combined with a special feeding schedule helps preterm babies start eating by mouth more quickly and gain weight. It is designed for stable preterm infants born at 29-33 weeks.
AydinAges 7 months–8 months - NCT04856501Recruiting
Parenting support for preterm toddlers’ brain and self-control
This study tests whether a responsive parenting program helps toddlers born early think, learn, and manage behavior more easily. It also checks whether families can complete toddler brain and behavior assessments (including brain scans).
Houston, TexasAges 1.3 years–2.5 years - NCT07101640RecruitingPhase 1/Phase 2
Montelukast study for breathing problems in premature infants
This trial tests if the medicine montelukast can help very premature babies on breathing machines. It aims to see if it improves lung development and makes it easier for them to breathe on their own.
Little Rock, ArkansasAges 1 week–4 weeks - NCT06965530Recruiting
Food support for pregnant patients with Medicaid
This trial provides medically tailored groceries to pregnant people who are food insecure. It tests whether better nutrition during pregnancy can improve health for you and your baby.
Cleveland, OhioAges 18–55 - NCT06830226Enrolling by invitation
Domperidone and preterm breast milk nutrients
This study looks at how domperidone, a medicine used to help increase breast milk supply, affects the nutritional content of breast milk from mothers of premature babies. By understanding this, doctors can better support your baby's growth.
LisbonAges Any age - NCT06007547RecruitingPhase 4
Preventive surfactant therapy for preterm babies
This trial tests whether giving surfactant (a foam that helps lungs stay open) before breathing problems start can help very premature babies (born before 30 weeks) breathe better. It might reduce the need for a breathing tube.
Evanston, IllinoisAges Up to 15 minutes - NCT06643598Recruiting
Virtual and lived-experience support for newborns with brain challenges
This study tests whether a program that combines virtual support and a peer who has been through it can help parents of newborns with certain brain conditions. It is designed for families living in rural areas and aims to improve children's recovery.
Madison, WisconsinAges Up to 5 years - NCT06521398Recruiting
Postpartum Care for Preterm NICU Babies
This study focuses on helping new mothers of preterm babies (born before 34 weeks) who are getting care in the NICU at HUP. It tests a program to support your transition home after giving birth, so you and your baby can thrive.
Philadelphia, PennsylvaniaAges 16 years+ - NCT06063122Recruiting
Device to help preterm babies tell speech sounds apart
This study tests a new device that plays special sounds to help preterm babies learn to tell different speech sounds apart. It is for babies born between 32 and 35 weeks of pregnancy to see if the device can improve their hearing and brain development.
Atlanta, GeorgiaAges 7 months–8 months - NCT06417385Recruiting
Nerve stimulation to improve breastfeeding before hospital discharge
This trial tests whether a gentle nerve stimulation (using a small device on the ear) during breastfeeding can help babies feed better before leaving the hospital. It is for babies born at 35 weeks or later who are stable but struggling to breastfeed, even with help from a lactation consultant.
Charleston, South CarolinaAges 8 months+ - NCT06340971Recruiting
Air pollution and pregnancy study
This study looks at how air pollution might affect pregnancy. Researchers will review existing health records from pregnant women to see if there are links between pollution levels and pregnancy outcomes.
LondonAges 18 years+ - NCT06036446Recruiting
Late cerclage for preventing early birth in high-risk pregnancies
This trial tests if placing a stitch in the cervix (cerclage) between 24 and 27 weeks of pregnancy can help prevent preterm birth in women whose cervix is short. It may be an option for those who find out late in pregnancy that they are at risk.
Charlotte, North CarolinaAges 18–50 - NCT05698836Enrolling by invitation
Health check study for preterm- and term-born children
This study looks at cardiovascular (heart and blood vessel) health in children who were born preterm or at full term. It may help researchers understand early-life factors that affect heart and metabolic health later.
OxfordAges 3–9 - NCT03819933Recruiting
Family counseling support for very early preterm birth
This trial studies a better way to provide counseling to families when a baby is expected to be born very early (between about 22 and 25 weeks). It may help you and your partner feel more prepared for the NICU and what to expect next.
Boston, MassachusettsAges 18–99 - NCT05410340Enrolling by invitation
EEG and near-infrared testing in newborns
This study checks how newborn brains respond by using painless sensors on the head. It focuses on babies during their first month after birth, to help researchers understand early brain function and development.
Salamanca, SalamancaAges 1 week–1 month - NCT05336890Recruiting
Using past oxygen data to predict risks after premature birth
This study builds a personalized computer model that uses earlier breathing/oxygen information from preterm infants to predict possible health or development outcomes by preschool age. It may help families and doctors better estimate risks and plan support, using information already collected in a previous study.
Chicago, IllinoisAges 7 months–6.9 years - NCT04685356Recruiting
Testing IBAIP for brain development in very preterm babies
This study looks at whether the IBAIP program can improve neurodevelopment (how the brain grows and works) in babies born very early. Babies are included only if they have a normal early neurological exam after being “corrected for prematurity.”
AngersAges 6 months–7 months - NCT04661553Recruiting
Special camera test to spot early cervical changes in pregnancy
This trial tests a detailed “polarimetric colposcopy” camera exam to better detect early changes in the cervix during pregnancy. Results may help guide closer monitoring in pregnancy, especially if there are signs that the cervix may start to change too soon.
Le Kremlin-Bicêtre, FranceAges 18 years+ - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT07152106Recruiting
Amniotic fluid and the preterm baby's gut
This study looks at the fluid around your baby (amniotic fluid) and how it might affect your baby's gut health if they are born early. It may help doctors understand how to better care for preterm infants.
AmsterdamAges 16 years+ - NCT04047849RecruitingPhase 4
Antibiotics for early water breaking before 23 weeks
This trial studies whether taking antibiotics can help in pregnancies where the “water” broke early (before 23 weeks) but you don’t have a fever. It aims to reduce complications while keeping both mother and baby as safe as possible.
Baton Rouge, LouisianaAges 18 years+ - NCT06965842Enrolling by invitation
Video training guide for preterm infant development
This trial tests a video system to help guide development for preterm babies. It may help infants born very early or with very low birth weight who also have brain damage.
Seoul, Jongno-guAges Up to 1 month - NCT04380051Recruiting
Sensory touch therapy to help parents bond with very preterm babies
This study tests whether a gentle sensory “stimulation” approach can improve how parents and very preterm babies interact and support the baby’s social development. If you qualify, you and your baby would be asked to take part so researchers can see whether this early intervention helps bonding and social skills.
ReimsAges Up to 1 day
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Common questions
- Are there clinical trials for premature birth?
- Yes. Clin2 currently lists 59 recruiting premature birth studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature birth trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature birth trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.