Clinical trials
Premature Rupture of Fetal Membranes clinical trials
Below are recruiting premature rupture of fetal membranes clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04047849RecruitingPhase 4
Antibiotics for early water breaking before 23 weeks
This trial studies whether taking antibiotics can help in pregnancies where the “water” broke early (before 23 weeks) but you don’t have a fever. It aims to reduce complications while keeping both mother and baby as safe as possible.
Baton Rouge, LouisianaAges 18 years+ - NCT07826533Recruiting
Intravenous papaverine for term prelabour rupture of membranes
This study tests whether giving papaverine through a vein can help start labour in women whose water has broken but who are not yet having contractions. Papaverine is a medicine that relaxes smooth muscles, which may help the cervix prepare for delivery.
HolonAges Any age - NCT07660393Recruiting
Virtual reality glasses for women with early water breaking
This study tests whether wearing virtual reality glasses can help reduce stress and anxiety in pregnant women who have experienced premature rupture of membranes (water breaking early). It is designed for women carrying a single baby who are between 24 and 37 weeks of pregnancy.
KonyaAges 18–50 - NCT07559071Recruiting
Emotional Freedom and Music Therapy for High-Risk Pregnancy
This study tests whether emotional freedom technique (a tapping-based stress-relief method) and music therapy can help reduce anxiety in pregnant women diagnosed with preterm premature rupture of membranes (PPROM)—a condition where the amniotic sac breaks early. The goal is to see if these therapies improve emotional well-being during a stressful pregnancy situation.
Konya, KonyaAges 18 years+ - NCT07366359Recruiting
Comparing two labor-starting medicines after water breaks early
This study compares two medicines to start labor after your water breaks early: one medicine (PGE2) is given first, then another (oxytocin), versus giving oxytocin alone. It aims to see which approach leads to a safer and smoother delivery.
Hanoi, HanoiAges 18 years+ - NCT05469984Recruiting
Two antibiotic plans for water breaking before labor
This trial compares two different “preventive” antibiotic schedules for pregnant people whose water breaks more than 18 hours before labor, or who go into preterm labor. The goal is to see which plan better helps mother and baby by reducing infection-related complications.
NahariyaAges 18–48 - NCT02997345Recruiting
PPROM pregnancy registry for women under 37 weeks
This registry is collecting information from pregnant people diagnosed with preterm premature rupture of membranes (PPROM) before 37 weeks. It may help researchers better understand PPROM and improve care for future patients.
Denver, ColoradoAges 14–55 - NCT07844876Recruiting
Improving pregnancy problem prediction for African mothers
This study looks at improving how doctors predict pregnancy problems in African women. It will follow first-time mothers early in pregnancy to find better ways to keep you and your baby safe.
KampalaAges 18 years+ - NCT07802041Enrolling by invitation
Early induction vs waiting for labor after water breaks
This trial compares inducing labor soon after your water breaks to waiting and seeing if labor starts on its own. It aims to find the safest approach for you and your baby.
IslamabadAges 18–45 - NCT07792083Recruiting
Amniotic fluid study for short cervix or early water break
This study looks at the fluid around the baby (amniotic fluid) in women with a short cervix or with early breaking of the water (premature rupture of membranes). The goal is to better understand these conditions and possibly improve care.
Roma, RMAges 18 years+ - NCT07517796RecruitingPhase 4
IV Papaverine to Help Induce Labor in Pregnancies with Broken Water
This study tests whether an IV medication called papaverine can help induce labor in pregnant people at term (37+ weeks) whose water has broken but labor hasn't started yet. The goal is to see if this medication makes labor start naturally and reduces the need for cesarean delivery.
Nahariya, IsraelAges 18–45
Hear when a new Premature Rupture of Fetal Membranes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for premature rupture of fetal membranes?
- Yes. Clin2 currently lists 11 recruiting premature rupture of fetal membranes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a premature rupture of fetal membranes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a premature rupture of fetal membranes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.