Clinical trials
Anterior Cruciate Ligament Rupture clinical trials
Below are recruiting anterior cruciate ligament rupture clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02511158Recruiting
Knee ligament surgery study after ACL reconstruction
This study follows people who have a knee ligament tear and undergo surgery to rebuild the ligament. It may help doctors better understand recovery and outcomes after different surgical techniques.
ParisAges 7 years+ - NCT04390035Recruiting
Blood-flow training after ACL surgery for teens
This trial looks at whether a special exercise method that changes blood flow during physical therapy (called BFRT) can improve recovery after ACL reconstruction in teens. It may help strength and rehab progress, but you would need to meet several surgery and safety requirements and attend many PT visits.
Atlanta, GeorgiaAges 12–18 - NCT06194682Recruiting
ACL reconstruction follow-up study
This study follows people who have had or will have ACL reconstruction surgery at this hospital. It helps doctors learn more about how patients recover after ACL surgery over the long term.
MilanAges 18–65 - NCT06294314Recruiting
ACL surgery with bone marrow and internal brace for return to sports
This trial studies a new way to reconstruct a torn ACL using your own bone marrow cells and a special internal brace to help you return to sports. It's for young athletes who haven't had ACL surgery before.
Huntington, West VirginiaAges 14–26 - NCT02771548Recruiting
Strength and movement study after ACL knee surgery
This study looks at how your knee moves during daily-style tasks and how strong your muscles are after ACL surgery. It may help researchers understand recovery and improvement after reconstruction.
Dublin, LeinsterAges 13–45 - NCT06195423Recruiting
Stopping knee arthritis after an ACL tear
This study tests a home exercise program to prevent knee arthritis after an ACL tear. If you had ACL surgery 9 to 36 months ago and still have some knee symptoms, this program may help protect your knee in the long run.
Vancouver, British ColumbiaAges 16–35 - NCT05747079Recruiting
Early versus delayed surgery after a new ACL tear
This study compares immediate surgery versus waiting a short time for people with a new ACL injury. It aims to see which timing leads to better recovery and knee function.
LeuvenAges 16 years+ - NCT06379308Recruiting
ACL revision surgery study in France
This study looks at people who need a second ACL surgery (revision). It helps doctors learn more about these procedures to improve care.
Saint-EtienneAges 18 years+ - NCT04781920Recruiting
Follow-up after ACL ligament surgery
This study is checking how people are doing after anterior cruciate ligament (ACL) reconstruction (a surgery to repair a knee ligament). It may help researchers understand recovery and long-term outcomes after ACL surgery.
Saint-EtienneAges 18 years+ - NCT07671729Recruiting
Comparing two tendon grafts for ACL surgery
This study compares two types of tendon grafts (from your kneecap tendon or from a tendon in your leg) for ACL reconstruction. The goal is to see which one works better for getting you back to normal activity.
Istanbul, BesiktasAges 18–50 - NCT06190223Recruiting
ACL repair using kneecap tendon with press-fit method
This study looks at a specific ACL reconstruction technique using a graft from your kneecap tendon that is fixed with a press-fit method. It aims to determine how well patients recover after at least one year.
AnkaraAges 18–55 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07333092Recruiting
Balance exercises after ACL surgery
This trial tests whether special balance and movement exercises (proprioceptive exercises) help people recover better after ACL knee surgery. You would start these exercises during the second week of your rehab program.
SanliurfaAges 20–40 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT05174611RecruitingPhase 2
Vitamin D to strengthen the thigh after ACL surgery
This Phase 2 study tests whether taking vitamin D can improve thigh (quadriceps) muscle strength after ACL reconstruction. It targets people with low vitamin D levels that persist after surgery and weaker thigh strength on the injured side.
Hong KongAges 18–40 - NCT06259968Recruiting
Electrical stimulation after ACL surgery recovery trial
This trial tests if adding electrical stimulation to standard physical therapy helps people recover strength and movement after ACL reconstruction surgery. It compares two rehab programs starting within days after surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06505525Recruiting
ACL reconstruction: adding extra support vs standard surgery
This trial compares two surgical techniques for ACL reconstruction. The standard method repairs the ACL inside the knee joint, while the new method also adds extra support outside the joint. The study aims to see which approach gives better stability and recovery for people with specific risk factors, like being a young athlete or having a chronic ACL tear.
São Paulo, São PauloAges 14–40 - NCT06727344Recruiting
ACL recovery with blood flow restriction therapy
This study tests whether adding blood flow restriction (gentle pressure applied to the upper leg during exercise) to standard treatment can help heal a completely torn ACL. If you have a full ACL tear and can speak Greek, you may be able to join.
NicosiaAges 18–40 - NCT06905691Recruiting
Eccentric training after ACL reconstruction
This study tests if a specific exercise (eccentric training) helps people recover better after ACL surgery. You may join if you are between 18 and 40 and are scheduled for this surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06955026Recruiting
Hockey slideboard and blood flow restriction for ACL rehab
This trial tests if using a hockey slideboard with blood flow restriction (a special band that limits blood flow during exercise) helps recovery after ACL surgery. It may improve muscle strength and function faster.
Odorheiu Secuiesc, RomaniaAges 18–45 - NCT07129694Enrolling by invitation
Testing a new lab-grown ligament for ACL repair
This study tests a new, lab-grown ligament made from biological tissue for ACL reconstruction. It may offer a regenerative option for people with a recent ACL tear who need surgery.
Hirosaki, AomoriAges 18–44
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Common questions
- Are there clinical trials for anterior cruciate ligament rupture?
- Yes. Clin2 currently lists 62 recruiting anterior cruciate ligament rupture studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament rupture trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament rupture trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
- Anterior Cruciate Ligament (ACL) Reconstruction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.