Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 382 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06688851Recruiting
Custom implants for jaw cysts
This study tests custom-made implants to help treat jaw cysts that are near important structures. It may be an option for people whose cysts are in tricky locations where standard surgery might be risky.
Budapest, BudapestAges 18 years+ - NCT06697938Recruiting
Chemo plus radiation vs. chemo alone for locally advanced breast cancer
This trial compares two treatments for locally advanced breast cancer: chemotherapy before surgery plus radiation, versus chemotherapy before surgery alone. The goal is to see which approach works better for this specific type of cancer.
Chengdu, SichuanAges 18–70 - NCT06698757RecruitingPhase 2
Testing different cycles of sintilimab before surgery for colorectal cancer
This trial tests how many cycles of the immunotherapy drug sintilimab given before surgery help treat colorectal cancer that is mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H). It is for locally advanced cancer that has not spread to other parts of the body.
Zheng'zhou, HenanAges 18–75 - NCT06699446Recruiting
Seamless care from before to after heart surgery
This study is for people who are getting ready for heart surgery and want to follow a program that helps them prepare and recover. It tests a seamless approach from before surgery through rehabilitation, focusing on exercise and support.
Hanover, Lower SaxonyAges 18 years+ - NCT06700291Recruiting
Frailty and thinking problems after surgery in older adults
This study looks at how frailty (a state of being physically weak and less resilient) before hip or knee replacement surgery affects thinking and memory problems after surgery in older adults. It aims to help identify patients who may need extra support.
TbilisiAges 65 years+ - NCT07687875RecruitingPhase 1
Virus therapy plus immunotherapy before surgery for rectal cancer
This trial tests a combination of a cancer-killing virus (oncolytic virotherapy) and an immunotherapy drug (pembrolizumab) given before surgery for a certain type of rectal cancer. It aims to see if this approach helps shrink the tumor and improve outcomes for patients whose tumors have a normal DNA repair system (pMMR).
Copenhagen, Captial RegionAges 18 years+ - NCT07255729Recruiting
Blood Test for Colon Cancer Staging
This study looks at a new blood test that may help doctors better understand how far colon cancer has spread. By testing a sample of your blood (taken before surgery), researchers hope to find patterns that predict the stage of cancer and help guide treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT06716892Recruiting
Non-invasive imaging for head and neck tumors
This trial is testing a new, non-invasive imaging technique called MSOT to look at head and neck tumors. It compares images from people with tumors to healthy volunteers, aiming to improve how doctors evaluate tissue before surgery.
Erlangen, BavariaAges 18 years+ - NCT06721286RecruitingPhase 2
Combining immunotherapy with chemotherapy before surgery for bile duct cancer
This trial tests whether adding an immunotherapy drug (toripalimab) to standard chemotherapy before surgery can improve outcomes for people with intrahepatic cholangiocarcinoma that can be surgically removed. It's for patients who haven't had prior treatment for their cancer and are in good overall health.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06723327Recruiting
How urine culture timing affects kidney stone surgery results
This study checks if taking a urine culture two weeks before kidney stone surgery affects outcomes. It may help ensure your surgery goes smoothly by confirming your urine is free of infection.
TekirdağAges 18 years+ - NCT06730529Recruiting
Using 68Ga-FAPI PET/CT scan for thyroid cancer lymph nodes
This study uses a special type of PET/CT scan (68Ga-FAPI) to see how well it finds cancer spread in lymph nodes before thyroid cancer surgery. It may help doctors plan your treatment more accurately.
Shanghai, Shanghai MunicipalityAges 16–80 - NCT06755866Recruiting
Predicting chemo-radiation response with improved MRI for esophageal cancer
This trial uses a special MRI technique to see if it can predict how well esophageal cancer responds to chemo-radiotherapy before surgery. It may help doctors choose the best treatment plan for you.
Kunming, YunnanAges 18–80 - NCT06760221Recruiting
Spotlight on bone cancer: SBRT plus surgery
This trial tests if giving a high dose of focused radiation (SBRT) before surgery can improve outcomes for people with aggressive soft tissue sarcoma in an arm or leg. You may be able to avoid chemotherapy and still have a good result.
Hangzhou, ZhejiangAges 18–80 - NCT06765538Recruiting
Video vs. in-person anesthesia check before surgery
This trial compares a video call with a face-to-face meeting for your pre-surgery anesthesia check. The goal is to see if the video option works just as well, which could save you a trip to the hospital.
Copenhagen, Region SjællandAges 18 years+ - NCT06775977Recruiting
Ultrasound contrast for bladder cancer staging
This trial uses a special ultrasound with contrast dye to get a clearer picture of bladder cancer before any treatment. It aims to improve how doctors determine the stage of the cancer, which helps guide the best treatment plan.
Guangzhou, GuangdongAges 18–75 - NCT06780735Recruiting
Breast-sparing surgery using a special dye after chemo
This trial tests a technique where doctors use a special dye (ICG) to guide breast-conserving surgery in patients whose tumors have shrunk enough after chemotherapy. The goal is to remove only the cancer while saving as much healthy breast tissue as possible.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT06784089Recruiting
Hip fracture type, nutrition and pain after surgery
This study looks at how a person's nutrition before hip surgery relates to their pain levels after surgery. It aims to help doctors improve recovery for older adults.
AnkaraAges 65 years+ - NCT06784791RecruitingPhase 2
Amivantamab before surgery for EGFR-mutant lung cancer
This trial tests a new drug, amivantamab, given before surgery for people with a specific EGFR-mutated lung cancer. It aims to shrink tumors and improve surgical outcomes, and may be combined with standard chemotherapy in some patients.
HasseltAges 18 years+ - NCT06785389Recruiting
How fear before surgery affects pain and recovery
This study looks at how feeling scared or anxious before surgery might affect your pain and recovery afterward. It aims to help improve care for future patients.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06791005RecruitingPhase 3
Timing of carbon nanoparticles injection for thyroid cancer
This trial tests whether the timing of a carbon nanoparticle injection during thyroid cancer surgery improves outcomes. It may help patients who need their whole thyroid removed and have cancer in both lobes or spread to lymph nodes.
Xi'an, ShaanxiAges 16–80 - NCT06805721Recruiting
Observational study of endovascular treatment for brain and spine vessel conditions
This study follows patients of any age who are having a minimally invasive procedure (endovascular treatment) for blood vessel problems in the brain or spine. It looks at how patients do before and after the procedure, any complications, and what factors might predict a good outcome.
MilanAges Any age - NCT06812728RecruitingPhase 2
Chemo and radiation before surgery for advanced rectal cancer
This trial tests giving a strong chemotherapy combination (FOLFIRINOX) followed by radiation before surgery for locally advanced rectal cancer. If you have stage 3 or high-risk stage 2 rectal cancer that has not spread, this approach may shrink the tumor and improve outcomes.
Shibīn al Kawm, MenoufiaAges 18–70 - NCT06826885Recruiting
Comparing two types of radiation for breast cancer
This trial is testing how well two different radiation techniques, IMPT and IMRT, work for treating breast cancer. It aims to see which one is safer and more effective, so you might benefit from a potentially better treatment approach.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 382 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.