Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 375 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT06976710Recruiting
Improving communication before colon or rectal cancer surgery
This trial is testing a way to improve communication between you and your surgical team before colon or rectal cancer surgery. It's for adults having major surgery that aims to cure their cancer.
Coffs Harbour, New South WalesAges 18 years+ - NCT07549113Recruiting
Preoperative prep methods for large abdominal wall hernias
This trial compares different ways to prepare your body before surgery to repair a large hernia (bulge in your abdominal wall). The goal is to find the best approach to help you heal well after surgery.
Krasnodar, Krasnodarskiy KrayAges 18 years+ - NCT07511673Recruiting
Dental screening before heart valve surgery
This trial tests whether a dental checkup before heart valve surgery can improve recovery and prevent complications. If you are scheduled for a heart valve procedure, you may be able to join.
GothenburgAges 18 years+ - NCT06849583Enrolling by invitation
Testing how pre-surgery checkups affect anxiety and satisfaction
This study looks at how talking to an anesthesiologist before surgery affects your worry and how happy you are with your care. It compares different ways of checking anxiety to find which one works best.
IstanbulAges 16–85 - NCT06853431RecruitingPhase 4
Pre-surgery calming medicine for children ages 1 to 6
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Wenzhou, ZhejiangAges 1–6 - NCT05774678RecruitingPhase 3
Pre-surgery radiation options for invasive breast cancer
This trial compares two schedules of radiation given before mastectomy to see which works better for invasive breast cancer, followed by immediate breast reconstruction. It also studies tiny “biomarker” signals in tissue to learn why one radiation approach may help more.
Houston, TexasAges 18 years+ - NCT07861438Enrolling by invitation
Funny video before surgery to ease anxiety
This study tests whether watching a funny video before gallbladder removal surgery can help reduce anxiety and improve recovery. It may help you feel more relaxed and recover better after your operation.
Istanbul, BaşakşehirAges 18 years+ - NCT07650695Recruiting
Virtual Reality to Help Children Feel Calm Before Surgery
This study tests whether using virtual reality on a smartphone can help children ages 3–12 feel less anxious before planned surgery. The goal is to see if this relaxing tool can reduce worry and make the hospital experience easier for kids and families.
Madrid, MujerAges 3–12 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07336160Recruiting
Nutrition before knee replacement surgery
This trial studies a special nutrition plan before knee replacement surgery to see if it helps recovery. Participants follow enhanced recovery guidelines for eating and drinking before their operation.
Istanbul, IstanbulAges 18 years+ - NCT06837415Enrolling by invitation
Does Pre-Surgery Anxiety Relate to Blood Eosinophil Levels?
This study looks at whether how anxious people feel before surgery is linked to a type of white blood cell called an eosinophil. If you have a planned surgery, they will check your anxiety level and take a blood sample to see if there's a connection.
IstanbulAges 16–85 - NCT04715581Recruiting
Pre-surgery rehab program for frail older adults having stomach surgery
This trial studies a “prehabilitation” program—exercise and coaching before surgery—to help frail older adults recover better after major digestive cancer surgery. It may help you strengthen your body and function before the operation, which can improve outcomes after surgery.
Beijing, Beijing MunicipalityAges 65–89 - NCT05461157Enrolling by invitation
Silicone ointment before head or neck surgery to improve healing
This trial studies whether applying a silicone ointment before and around the time of planned head or neck surgery can improve how your wound heals after surgery. It may help reduce problems like poor scar healing, but you can only join if you meet specific medical and safety requirements.
New Haven, ConnecticutAges 18 years+ - NCT06487481RecruitingPhase 1
Radiation before surgery for recurrent adrenal cancer
This trial tests whether giving radiation before surgery helps people with adrenal cancer that has come back after previous treatment. It aims to see if this approach can improve outcomes for patients who can have surgery at the NIH.
Bethesda, MarylandAges 18–120 - NCT07822763Recruiting
Carbohydrate drink before weight-loss surgery for faster recovery
This study tests whether drinking a special carbohydrate drink before weight-loss surgery can help your stomach and intestines recover faster after the operation. If you have metabolic syndrome and are planning certain types of bariatric surgery, this may help you improve your recovery.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT07425405Recruiting
Screen time and surgery anxiety in young children
This study looks at how daily screen time affects anxiety in children aged 2 to 5 years before a planned surgery. It aims to find if more screen time is linked to more anxiety, which could help prepare children better for surgery.
Istanbul, küçükçekmeceAges 2–5 - NCT04330456Recruiting
Radiation plus surgery for first soft tissue sarcoma
This trial studies a treatment plan for newly diagnosed soft tissue sarcoma that combines precisely targeted radiation before surgery and conformal radiation after surgery. It may help by improving tumor control while allowing the surgeon to remove the tumor safely.
Saint PetersburgAges 18–75 - NCT04699292Recruiting
Registry study for local treatment in soft tissue sarcoma
This registry collects coded information about adults with a specific soft tissue sarcoma (MLS) to better understand how local treatments help. If you qualify, you don’t necessarily receive a new drug in this study—your data is used to improve future care.
AmsterdamAges 18 years+ - NCT05603078Recruiting
Breast cancer surgery with a tumor-bed boost and standard radiation
This study looks at whether adding extra targeted radiation to the tumor area before breast-conserving surgery, then using modern breast surgery techniques and whole-breast radiation afterward, improves outcomes for early-stage breast cancer. You may be offered a treatment plan designed to better treat the area where the tumor was removed.
Beijing, Beijing MunicipalityAges Up to 55 years - NCT07855627Recruiting
Predicting lymphedema risk before surgery
This study looks at whether a simple measurement taken before surgery can help predict if you might develop lymphedema (arm swelling) after treatment. It is for women with newly diagnosed inflammatory breast cancer who are planning to have standard treatments.
Houston, TexasAges 18 years+ - NCT06472583RecruitingPhase 2
Immunotherapy and radiation before breast cancer surgery
This trial tests giving immunotherapy combined with a precise, high-dose radiation boost before surgery for HER2-negative breast cancer. The goal is to see if this approach can improve outcomes, especially for cancers that are more advanced or have spread to a few other spots in the body.
GliwiceAges 18 years+ - NCT07817758Recruiting
Sarcopenia and surgery outcomes in older gastrointestinal cancer patients
This trial looks at whether low muscle mass (sarcopenia) before surgery affects recovery for older adults with gastrointestinal cancer. It may help doctors personalize care and improve outcomes.
Van, VanAges 60 years+ - NCT07800364Recruiting
Tizanidine before leg surgery for better pain and sleep
This study tests whether taking a muscle relaxant called tizanidine before leg surgery improves pain control and sleep quality after the operation. It may help you recover more comfortably.
Tanta, Gharbia GovernorateAges 21 years+
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Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 375 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.