Clinical trials
Pulp Disease, Dental clinical trials
Below are recruiting pulp disease, dental clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06196515RecruitingPhase 2/Phase 3
Study of a new nano-medication for infected tooth root canals
This trial tests whether a nano-scale calcium hydroxide paste works better than standard treatments for tooth infections. If you have a permanent molar with signs of infection around the root tip, this study may be an option.
CairoAges 21–49 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT06854744Recruiting
Olive oil and zinc oxide for baby tooth root canals
This study tests a mixture of olive oil and zinc oxide to treat infected baby molars. It aims to see if this natural treatment works as well as standard medicine for stopping infection and saving the tooth.
Tanta, Gharbia GovernorateAges 4–7 - NCT07041905Recruiting
Comparing two ways to treat deep cavities in back teeth
This study compares two ways of removing deep tooth decay to see which keeps the tooth nerve healthy and causes less pain afterward. It's for people who have two deep cavities on opposite sides of their mouth and want to help find the best treatment.
AdanaAges 15–55 - NCT06173167Recruiting
Same-day zirconia crowns for back teeth
This study tests a new type of same-day zirconia crown made in the dentist's office. It compares two different zirconia materials for strength and durability, and aims to see which one works best for back teeth.
Ann Arbor, MichiganAges 18 years+ - NCT05924373RecruitingPhase 2
Stem cell treatment for chronic gum disease defects
This Phase 2 trial studies whether injections of human dental pulp stem cells can improve chronic periodontitis (long-term gum disease) by helping repair damaged bone around teeth. If you have a specific type of bone defect and moderate gum pocket depth, you may be eligible and could benefit from a novel regenerative approach.
Beijing, BeijngAges 18–65 - NCT04605445Recruiting
One vs two dentist visits for infected root canals
This study compares whether treating an infected, dead tooth in one visit works as well as using two visits. It may help you and your dentist choose the simplest schedule while still clearing infection and supporting healing.
Vaxjo, Kronoberg CountyAges 18 years+ - NCT06569329Recruiting
Extra cleaning for infected root canals
This study tests if extra cleaning steps after a standard root canal can remove more bacteria from an infected tooth. It is for adults with a dead nerve and an infection at the root tip in a single-rooted premolar that has never been treated before.
Iowa City, IowaAges 18–95 - NCT06447753Recruiting
Comparing two treatments for tooth pain in back molars
This study compares two ways to treat a deep cavity in a back molar that has a moderately inflamed nerve. If you have a painful deep cavity, this trial will test if a partial or complete nerve treatment works better to save your tooth.
Rohtak, HaryanaAges 18–60 - NCT07578662Recruiting
Direct Pulp Capping for Deep Cavities in Back Teeth
This study tests a treatment where dentists cap (seal) an exposed tooth nerve in deep cavities of back teeth to see if it heals properly. This might help save your tooth instead of needing a root canal.
Rohtak, HaryanaAges 15–40 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+
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Common questions
- Are there clinical trials for pulp disease, dental?
- Yes. Clin2 currently lists 17 recruiting pulp disease, dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulp disease, dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulp disease, dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.