Clinical trials
Dental Caries clinical trials
Below are recruiting dental caries clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06365281Recruiting
Cavity risk study for adults 35–44 years old
This study looks at how common cavities are and what factors might increase the risk of them in people ages 35–44. By joining, you'll help researchers learn more about oral health in this age group among Egyptians.
GizaAges 35–44 - NCT06558955Recruiting
Preventing baby tooth decay with text support for new moms
This study tests a program that uses text messages and online support to help new moms prevent cavities in their baby's teeth. It provides tips and support from other parents to make dental care easier for your little one.
SingaporeAges 21 years+ - NCT07041905Recruiting
Comparing two ways to treat deep cavities in back teeth
This study compares two ways of removing deep tooth decay to see which keeps the tooth nerve healthy and causes less pain afterward. It's for people who have two deep cavities on opposite sides of their mouth and want to help find the best treatment.
AdanaAges 15–55 - NCT07555223Recruiting
Using 3D Scans to Better Detect Tooth Decay
This study tests whether special 3D imaging and intraoral scanning tools can help dentists better identify tooth decay and plaque buildup. Researchers want to see if these new methods work well and could improve how cavities are diagnosed.
Wondelgem, BotestraatAges 18–70 - NCT07560514Recruiting
Testing New Digital Tools to Detect Tooth Decay
This study tests new digital technologies—including a special camera called DIAGNOcam and AI software—to detect tooth decay early and accurately. If you have some cavities and healthy teeth in specific areas of your mouth, you may be eligible to help researchers improve how dentists find and diagnose tooth decay.
Martin, Žilina RegionAges 18–65 - NCT07609797Recruiting
Fluoride and Mouthwash Effects on Cavity Markers in Children
This study tests whether sodium fluoride and chlorhexidine (a prescription mouthwash) change certain markers in saliva that may relate to tooth decay in children with cavities. The goal is to understand if these common dental treatments affect the body's natural cavity-fighting substances.
Alanya, AntalyaAges 6–8 - NCT06944028Enrolling by invitation
Stepwise cavity treatment for deep decay in young teeth
This trial tests a gentler way to remove deep cavities in young permanent molars or premolars, aiming to save more of the tooth and protect the nerve. It may be an option for children and teens with deep decay that hasn't reached the pulp.
StockholmAges 8–19 - NCT07241052Recruiting
Probiotic spray for cavities in kids
This study tests a probiotic spray that you use in your mouth to help stop cavities from getting worse and to prevent new ones. It is for children ages 7–10 who already have at least one cavity.
Hà Nội, Sơn TâyAges 7–10 - NCT07262086Enrolling by invitation
Bioactive filling for deep cavities in back teeth
This trial tests a new type of self-hardening tooth-colored filling material that may help repair and protect deep cavities in back teeth. It is looking for people with two molars that need deep fillings, to see if the material stays strong and helpful over time.
Ismailia, IsmaliaAges 21–45 - NCT06999005Recruiting
Dental cavity treatment study for children ages 6-12
This study tests two gentle cavity treatments for children's permanent molars. It aims to find which method works best over two years.
Santos, São PauloAges 6–12 - NCT06991842Recruiting
Etching time for front tooth fillings
This study looks at how long to etch the tooth before placing a white filling on a front tooth. You may qualify if you need a standard filling on the side or corner of a front tooth.
Basel, Canton of Basel-CityAges 18 years+ - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07716254Recruiting
Dental cavity risk quiz study for Egyptian adults
This study tests a new questionnaire to see how well it can predict your risk of cavities. You will answer questions about your teeth and habits, and your answers will be compared with a dentist's exam.
Giza, Sixth of OctoberAges 18–65 - NCT07671651Recruiting
Ozone therapy for early tooth decay in children
This trial tests whether ozone therapy can help reverse the earliest stages of tooth decay (white spots on teeth) in children. Children aged 6–12 with small, non-cavity spots may benefit from this treatment instead of traditional fillings.
Istanbul, MaltepeAges 6–14 - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT06736964Enrolling by invitation
Testing new fillings for gum-line cavities in high-risk adults
This study tests how well two newer, tooth-friendly filling materials work for cavities at the gum line in people who are prone to tooth decay. If you need a couple of these fillings, this trial could help restore your teeth and protect them from future cavities.
CairoAges 25–45 - NCT07142629Enrolling by invitation
Cavity removal methods for MIH-affected molars
This trial compares two ways of removing tooth decay in children with a condition called MIH (which makes enamel weak and spotted). It tests whether selective or non-selective drilling works better for deep cavities, aiming to save the tooth and keep the nerve healthy.
IrbidAges 6–13 - NCT06006429Recruiting
Using a scanner to check teeth and gums
This study tests if a special intraoral scanner can help dentists find gum problems and tooth issues. If you have receding gums, you may be able to join.
ReimsAges 18 years+ - NCT07041164Recruiting
Light vs X-ray for finding cavities in kids' back teeth
This trial tests a new light-based tool (near-infrared light) compared to traditional X-rays to find hidden cavities between baby molars. The goal is to see if the light method is better at spotting cavities and if kids like it more.
BangkokAges 4–10 - NCT05606562Recruiting
Free dental care during hospital treatment for drug abuse
This study offers free dental treatment to people who are staying in a hospital for drug abuse treatment. It aims to see how adding dental care can help while you’re getting help for substance use.
Narvik, NordlandAges 18 years+ - NCT07611981Recruiting
Tooth Decay and Oral Health in Children With Learning Disabilities
This study compares tooth decay and brushing habits between children with specific learning disabilities and healthy children. Researchers want to understand if children with learning disabilities need special dental care strategies.
Alanya, AntalyaAges 7–12 - NCT04533113Recruiting
Tooth filling study using selective removal on back teeth
This study looks at a careful way of removing decayed tooth material on permanent back teeth. It is meant for people with early, reversible tooth nerve irritation, to see if the approach is effective and safe.
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT06727110Recruiting
New liquid treatment for tooth cavities
This study tests a new method to treat cavities that reach the middle layer of a tooth. It may help repair the tooth with a liquid that hardens into a filling. If you have a back tooth with a cavity that hasn't been filled yet, you might be eligible to join.
San Francisco, CaliforniaAges 18–64 - NCT07031856Recruiting
3D printed vs. CAD-CAM dental restorations comparison
This trial compares two modern ways to make partial dental restorations (like crowns or bridges): one using a 3D printer and the other using a computer-aided design and manufacturing (CAD-CAM) system. It aims to see which method works better for people who need a couple of teeth fixed.
Adana, SarıçamAges 18–65
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Dental Caries trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for dental caries?
- Yes. Clin2 currently lists 91 recruiting dental caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.