Clinical trials
Real World Data clinical trials
Below are recruiting real world data clinical trials, each written for real people, not researchers. We’re tracking 121 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05573893Recruiting
Real-world study of trastuzumab deruxtecan for HER2 breast cancer
This study looks at how people feel (patient-reported outcomes) and their real-world health data while they receive trastuzumab deruxtecan for advanced HER2-positive, HER2-low, or HER2-ultralow breast cancer. It helps researchers understand what outcomes happen outside of tightly controlled clinical trials.
AmbergAges 18–130 - NCT07107022Recruiting
Study of Penumbra System for acute ischemic stroke
This study is collecting information on how well the Penumbra System works and how safe it is when used to remove blood clots in people having a certain type of stroke. It is for patients who are eligible for mechanical thrombectomy (a procedure to remove the clot) using this device as the first treatment.
Nedlands, Western AustraliaAges 18–80 - NCT06240195Recruiting
Study of sacituzumab govitecan for advanced triple-negative breast cancer
This study is testing a drug called sacituzumab govitecan (SG) for people with advanced triple-negative breast cancer who have already had other treatments. The goal is to see how well the drug works and what side effects it causes, using your tumor samples to look for clues (biomarkers).
Rome, RomeAges 18 years+ - NCT07130968Enrolling by invitation
Heart and lung function study with exercise test and five-year follow-up
This study looks at how your heart and lungs work during exercise by using a special test called a cardiopulmonary exercise test (CPET). Researchers will follow you for up to five years to see how your health changes. It may help you understand your heart condition better and get more personalized care.
Guangzhou, GuangdongAges 18–80 - NCT04020536Recruiting
Real-world study for several infectious diseases
This study follows people with confirmed brucellosis, epidemic hemorrhagic fever, or kala-azar (visceral leishmaniasis) to understand how these infections behave in real life. It may help improve care by collecting evidence on diagnosis and treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07874451Recruiting
Study of BCL-2 inhibitor treatments for chronic lymphocytic leukemia
This study looks at real-world experiences of people with chronic lymphocytic leukemia (CLL) who have used or are using a type of targeted therapy called a BCL-2 inhibitor. It aims to understand how well these treatments work and their side effects in everyday practice.
Nanjing, JiangsuAges 18 years+ - NCT07724496Recruiting
H. pylori and stomach growth features study
This study looks at whether having H. pylori infection (a common stomach bacteria) and certain features of stomach growth can predict how early stomach cancer or pre-cancerous changes will behave and what your long-term outlook might be. You may be eligible if you are being treated with a camera-based removal procedure called endoscopic submucosal dissection (ESD).
Beijing, Beijing MunicipalityAges 18–80 - NCT07708935Recruiting
Study of young patients with solid tumors in China
This study looks at young people (40 or younger at diagnosis) with solid tumors in China. It aims to collect real-world information about their treatments and outcomes to find patterns that could help improve care.
ShanghaiAges 18–80 - NCT07696832Recruiting
Ivonescimab as first treatment for advanced lung cancer
This trial studies ivonescimab alone as a first treatment for people with advanced non-small cell lung cancer (NSCLC) that tests positive for PD-L1 and doesn't have certain gene changes. The goal is to see if it works and is safe in everyday medical practice.
Guangzhou, GuangdongAges 18 years+ - NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+ - NCT07642557Recruiting
Real-world remibrutinib use for chronic hives in Germany
This study observes how remibrutinib (a newer medication) works for chronic hives (CSU) when prescribed in routine clinical practice in Germany. Remibrutinib is used when standard allergy medications don't work well enough. The study tracks your symptoms and treatment over 24 months to understand how well it helps real patients.
DürenAges 18 years+ - NCT07640997Recruiting
Real-world study of aflibercept for age-related macular degeneration
This study follows patients receiving aflibercept 8 mg injections in the eye to treat wet age-related macular degeneration (nAMD), a condition that blurs central vision. The goal is to understand how well this treatment works and its safety in routine medical practice.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07633158Recruiting
Real-world study of tezepelumab for chronic nasal polyps
This study follows patients with chronic rhinosinusitis with nasal polyps (CRSwNP)—a condition causing blocked sinuses and nasal growths—who are starting a new biologic medication called tezepelumab. Researchers will track how symptoms and quality of life improve over time in everyday medical practice.
BochumAges 18–130 - NCT07621419Recruiting
Semaglutide for Type 2 Diabetes in Real-World Care
This study tests how well a diabetes medication called semaglutide works when prescribed in everyday clinical practice in Argentina. Semaglutide comes in two forms—a pill or an injection—and the study tracks how much it lowers blood sugar over one year.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07620626Recruiting
Study of Woven EndoBridge for Brain Aneurysm Treatment
This study looks at how well a special device called Woven EndoBridge works for treating brain aneurysms (weakened blood vessels in the brain). Researchers will review records of patients already treated and also follow new patients to see how they do over time.
BeijingAges Any age - NCT07618078Recruiting
Personalized Cancer Risk Assessment for Nasopharyngeal Cancer
This study helps doctors predict which patients with nasopharyngeal cancer (a cancer of the upper throat) will benefit most from additional chemotherapy after radiation treatment. It uses a special blood test and imaging to create a personalized risk score for each patient.
Beijing, Beijing MunicipalityAges 18–75 - NCT07613151Recruiting
Lobular breast cancer with low hormone receptors
This study looks at a rare type of breast cancer called invasive lobular carcinoma that has low or no hormone receptors. The goal is to learn more about how this cancer behaves, which may help improve future treatments.
PadovaAges 18 years+ - NCT07602088Recruiting
Real-world Study of Two Cancer Drugs for Chronic Lymphocytic Leukemia
This study follows patients with chronic lymphocytic leukemia (CLL)—a blood cancer—who are starting treatment with two drugs called ibrutinib and venetoclax together for a set period of time. Researchers want to understand how well this treatment works and how it affects patients' daily lives in real-world settings, rather than in a controlled lab environment.
BucharestAges 18 years+ - NCT07603193Enrolling by invitation
Real-World Study of Delgocitinib Cream for Chronic Hand Eczema
This study tracks how well delgocitinib cream works and how safe it is for people with chronic hand eczema in everyday use. Researchers collect information from your doctor visits to understand if this treatment helps manage your hand eczema symptoms.
Neu-IsenburgAges 18 years+ - NCT07601711Recruiting
Sulbactam-Durlobactam for Drug-Resistant Bacterial Infections
This study tracks hospitalized patients receiving a specific antibiotic combination (sulbactam-durlobactam) to treat a serious, hard-to-treat bacterial infection called CRAB. Researchers want to understand how well this treatment works in real-world hospital settings.
Chengdu, SichuanAges 18 years+ - NCT07587723Recruiting
Real-world study of eltrombopag treatment in immune thrombocytopenia
This study looks at how doctors treat immune thrombocytopenia (ITP)—a blood condition where your body attacks its own platelets—using a drug called eltrombopag. Researchers want to understand treatment patterns and outcomes in real-world practice to improve care.
BaselAges 18–100 - NCT07583485Recruiting
Tucatinib combination therapy for advanced HER2-positive breast cancer
This study watches how well a three-drug combination (tucatinib, capecitabine, and trastuzumab) works for women with breast cancer that has spread to other parts of the body and has a protein called HER2. You'll be treated as you normally would be in a clinic, and researchers will track how you respond.
Avellino, AVAges 18 years+ - NCT05053607Recruiting
Text and Fitbit monitoring during isatuximab treatment
This trial follows people with multiple myeloma who are getting isatuximab through a vein (IV). It tests how well real-world health tracking (text/app messages and Fitbit data) works during treatment, and whether it can help care teams understand your experience.
Houston, TexasAges 18 years+ - NCT07559695Recruiting
Menin inhibitor maintenance therapy after stem cell transplant
This study tracks how well a newer drug class (menin inhibitors) works to prevent acute leukemia from coming back after a stem cell transplant. You would be observed for safety and effectiveness if you're already taking one of these drugs.
Suzhou, JiangsuAges 15 years+
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Common questions
- Are there clinical trials for real world data?
- Yes. Clin2 currently lists 121 recruiting real world data studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a real world data trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a real world data trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.