Trazodone for depression with mild memory problems
Part of Mental health clinical trials.
This study tests how well the antidepressant trazodone works in older adults with major depression and mild cognitive impairment (early memory or thinking problems). It looks at real-world results in people starting this treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 55 years or older.
- You have major depression that is at least moderately severe.
- You also have mild memory or thinking problems (mild cognitive impairment).
- You are starting trazodone (extended-release) as a new treatment.
- You are not taking other antidepressants, mood stabilizers, or antipsychotics.
- You do not have bipolar disorder, schizophrenia, or another serious mental illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if taking psilocybin (a psychedelic drug) with trazodone (an antidepressant) can help people whose depression hasn't improved with at least two standard antidepressants. If you have treatment-resistant depression, this study might be an option.
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
This study tests whether trazodone, a sleep medication, improves insomnia in people 65 and older. You might benefit if you struggle with falling or staying asleep and are not already taking other sleep aids.
This trial tests if trazodone, a medication, can improve deep sleep in people who have both depression and insomnia. It aims to find a treatment that helps with both conditions at once.
This study looks at how a brain protein linked to Alzheimer’s disease changes over time in older adults who have major depression but no major memory problems. It involves brain scans, blood and urine tests, and a spinal fluid sample to better understand the connection between depression and brain aging.
This study tests how a medication called memantine affects memory and mood in people with major depression who are not currently taking antidepressants. It involves MRI scans and may help find new ways to treat depression.
Hear when a new Depression - Major Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.