Clinical trials
Refractory Angina clinical trials
Below are recruiting refractory angina clinical trials, each written for real people, not researchers. We’re tracking 5 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05711849RecruitingPhase 2
Stem cell treatment for long-lasting chest pain not helped by meds
This Phase 2 trial tests whether stem cells placed into the heart artery can safely reduce symptoms in people with “refractory” angina (chest pain) despite maximum heart-healthy medication. You may qualify if your chest pain is limiting your activity and other heart procedures (stents/bypass) aren’t possible or are too risky.
London, EnglandAges 18 years+ - NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
Phoenix, ArizonaAges 18 years+ - NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Mainz, Rhineland-PalatinateAges 18–85 - NCT01566175Recruiting
Neovasc device trial for hard-to-treat chest pain
This trial tests a device called the Neovasc Coronary Sinus Reducer to help people with long-lasting, hard-to-control chest pain (angina) who cannot have artery-opening procedures. It may improve symptoms by changing blood flow in the heart’s vein system.
Tel AvivAges 18 years+ - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Cincinnati, OhioAges 18–85
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Common questions
- Are there clinical trials for refractory angina?
- Yes. Clin2 currently lists 5 recruiting refractory angina studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a refractory angina trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a refractory angina trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.