Stem cell treatment for long-lasting chest pain not helped by meds
Part of Heart & circulation, Pain clinical trials.
This Phase 2 trial tests whether stem cells placed into the heart artery can safely reduce symptoms in people with “refractory” angina (chest pain) despite maximum heart-healthy medication. You may qualify if your chest pain is limiting your activity and other heart procedures (stents/bypass) aren’t possible or are too risky.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older
- Have ongoing chest pain from blocked heart arteries for at least 90 days despite max heart medications
- Have tried at least two types of anti-angina medicines at the highest tolerated doses for 2+ months and keep the plan steady for 12 months after randomization
- Have no good option for stent or bypass surgery, or your doctors say you’re too high-risk for it
- Have proof of reduced blood flow to the heart that can be triggered during a stress test (or by medication), and your treadmill test can last 2–8 minutes
- Have heart pumping strength (left ventricle ejection fraction) of at least 30% within the last 12 months, and be able to consent and attend follow-ups
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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