Clinical trials
Refractory Chronic Cough clinical trials
Below are recruiting refractory chronic cough clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06960759RecruitingPhase 2
Cough suppression therapy for chronic cough
This study tests a behavior-based therapy to help you gain control over a persistent cough that hasn't responded to other treatments. You will learn techniques to reduce coughing during a 4-week program.
Aurora, ColoradoAges 18–99 - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT06634823RecruitingEarly Phase 1
Steroid injection for chronic cough study
This study tests whether a steroid shot into the neck muscles can help people with a long-lasting, unexplained cough. It is for adults who have tried other treatments and still cough.
Charleston, South CarolinaAges 18 years+ - NCT05110144RecruitingPhase 2
Testing two doses of two nerve pain medicines for chronic cough
This Phase 2 study tests whether two doses of duloxetine and amitriptyline can reduce symptoms in people with chronic cough that hasn’t responded to usual care. You may join to see if these medicines lessen cough severity over an 8-week blinded treatment period.
Rochester, MinnesotaAges 18–75 - NCT05813223RecruitingEarly Phase 1
Gefapixant to study brain activity in chronic cough
This early study tests whether gefapixant changes brain activity related to cough in people with chronic cough that hasn’t improved with usual treatments. It may help researchers understand why chronic cough happens and how to better treat it.
Parkville, VictoriaAges 18–65 - NCT06600646Recruiting
Study of energy production in airway cells for chronic cough
This study looks at how the cells lining your airways make energy and whether this is different in people with chronic cough that doesn't get better with treatment or has no clear cause. It may help doctors understand why some people cough and find new ways to treat it.
Hamilton, OntarioAges 18–80 - NCT06706765RecruitingEarly Phase 1
Cough suppression therapy via group telehealth
This study tests a behavioral therapy delivered through group video calls to help people with a chronic dry cough that has no clear cause. It may offer a non-drug way to reduce coughing.
Missoula, MontanaAges 18 years+ - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT07070895Recruiting
Wellness app for chronic cough study
This trial tests a smartphone app and a smartwatch to help people with chronic cough that hasn't improved with standard care. You'll wear a watch to track your cough and use the app to learn management techniques.
Wilmington, DelawareAges 21 years+ - NCT07488598Recruiting
Behavioral therapy for hard-to-treat chronic cough
This trial tests a behavioral therapy for people whose chronic cough (lasting more than 8 weeks) hasn't improved with usual treatments like asthma or reflux medicine. You may join if your cough is triggered by things like talking, laughing, cold air, or irritants, and you have throat symptoms like irritation or hoarseness.
AsyutAges 18–50 - NCT07650084RecruitingPhase 3
Testing BLU-5937 for hard-to-treat chronic cough
This 24-week study tests whether a new medicine called BLU-5937 can help adults whose chronic cough hasn't improved with standard treatments. Chronic cough that lasts a year or longer can seriously affect quality of life, and this trial explores whether this drug might provide relief.
Leshan, SichuanAges 18–80 - NCT06542484Recruiting
Studying gefapixant for cough in kidney or bladder cancer
This study tests a medicine called gefapixant to see if it helps reduce chronic coughing in people with kidney or bladder cancer. You may qualify if your cough persists despite treatment and you have little to no smoking history.
Nagoya, Aichi-kenAges 18 years+
Hear when a new Refractory Chronic Cough trial opens
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Common questions
- Are there clinical trials for refractory chronic cough?
- Yes. Clin2 currently lists 12 recruiting refractory chronic cough studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a refractory chronic cough trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a refractory chronic cough trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.