Clinical trials
Rheumatoid arthritis clinical trials
An autoimmune condition that causes painful swelling in the joints. We’re tracking 262 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03770702RecruitingPhase 3
Testing blood pressure pills and statins for rheumatoid arthritis
This trial studies whether taking a cholesterol-lowering medicine (a statin) and a blood pressure medicine (an ARB) can better control rheumatoid arthritis activity. It may help people whose rheumatoid symptoms are not fully controlled with standard care.
TantaAges 18–65 - NCT04191395Recruiting
Study of treatments for long-term inflammatory diseases
This study looks at how chronic inflammatory illnesses progress over time and how treatments affect symptoms and disease markers. You may be invited if you’re receiving care for certain bowel, joint, or skin inflammatory conditions at the hospital.
BesançonAges 18 years+ - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT07533955RecruitingPhase 1
Testing JADE201 drug in rheumatoid arthritis patients
This early-stage study tests a new drug called JADE201 in people with rheumatoid arthritis (RA). Researchers want to see if it is safe and how the body handles it, which could lead to better RA treatments.
Chisinau, MoldovaAges 18–70 - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT00512239Recruiting
Tests outcomes in early inflammatory joint arthritis
This study looks at how early inflammatory joint diseases behave over time, especially early rheumatoid arthritis. It may help doctors better predict prognosis and tailor care for people with new symptoms.
Sherbrooke, QuebecAges 18–90 - NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT05039216Recruiting
Biobank for inflammatory arthritis and osteoporosis
This study collects and stores health information and samples for people with long-term inflammatory arthritis (like rheumatoid arthritis, spondyloarthritis, or psoriatic arthritis) or with osteoporosis. It helps researchers understand these conditions and may lead to better future treatments.
ToulouseAges 18–99 - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT07536529Recruiting
Oxidative Stress in Autoimmune Joint Diseases
This study looks at a type of cellular damage called oxidative stress in people with autoimmune joint diseases like rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis. Researchers want to understand how this damage relates to your disease and may help develop better treatments.
Larissa, ThessalyAges 18 years+ - NCT07455578RecruitingPhase 1
Study of S-4321 for people with autoimmune or immune diseases
This trial tests a new medicine, S-4321, for people with various autoimmune conditions like rheumatoid arthritis, psoriasis, eczema, or lupus. It aims to see if the drug is safe and can help control the overactive immune system.
Charlestown, New South WalesAges 18–75 - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+ - NCT07087912RecruitingPhase 4
Dengue vaccine safety in people with autoimmune rheumatic diseases
This study tests the safety and immune response of a dengue vaccine in people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are on low-dose or no immune-suppressing medications. It also includes healthy volunteers for comparison.
São Paulo, São PauloAges 12–59 - NCT01965132Recruiting
Biologic and targeted therapy registry for arthritis patients
This registry is collecting information about people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis who are starting or needing biologic or targeted medicines. It may help researchers better understand how these treatments work in real life.
SeoulAges 18 years+ - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07627893RecruitingPhase 2/Phase 3
Herbal supplement added to rheumatoid arthritis treatment
This trial tests whether a traditional Chinese herbal medicine, combined with your current rheumatoid arthritis medications, can reduce joint pain and swelling better than your current treatment alone. The study involves 6–12 months of treatment and regular check-ins with the research team.
SingaporeAges 21–70 - NCT04924270RecruitingPhase 2
Capsule stool transfer for newly diagnosed inflammatory bowel or joint disease
This Phase 2 study tests whether taking capsule stool (FMT) is safe and can help people who are newly diagnosed and haven’t started the usual medicines yet. Participants will also start the standard first-line treatment for their condition, and the study will compare safety and outcomes.
OdenseAges 18–75 - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07162311Enrolling by invitation
Home brain stimulation for rheumatoid arthritis pain
This trial tests if a gentle, home-based brain stimulation device (tDCS) can reduce chronic pain in people with rheumatoid arthritis who have low inflammation. It may offer a drug-free way to manage pain.
Porto Alegre, Rio Grande do SulAges 18–70 - NCT04876781Recruiting
Track safety of Xeljanz XR in Korea
This study collects real-world safety information about Xeljanz XR after it has been approved. It includes people with certain immune-related joint diseases and checks for side effects in everyday use.
SeoulAges 18 years+ - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+
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Common questions
- Are there clinical trials for rheumatoid arthritis?
- Yes. Clin2 currently lists 262 recruiting rheumatoid arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rheumatoid arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rheumatoid arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.